热痹康胶囊的提取工艺研究

详细信息    查看全文 | 推荐本文 |

英文篇名：Study on the Extraction Technology of Rebikang Capsule 作者：江丽芬 ; 方建康 ; 庞学丰 英文作者：JIANG Lifang;FANG Jiankang;PANG Xuefeng;Department of Pharmacy, Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine; 关键词：热痹康胶囊 ; 提取工艺 ; 水煎煮法 ; 正交试验 ; 痹证 英文关键词：Rebikang capsule;;Extraction Technology;;water decocting method;;HPLC;;arthromyodynia 中文刊名：ZZYY 英文刊名：Chinese Medicine Modern Distance Education of China 机构：广西中医药大学附属瑞康医院药学部; 出版日期：2019-01-10 出版单位：中国中医药现代远程教育 年：2019 期：v.17;No.297 语种：中文; 页：ZZYY201901051 页数：3 CN：01 ISSN：11-5024/R 分类号：118-120

摘要

目的探讨热痹康胶囊的水提取工艺条件。方法用薄层色谱法对方中防风、黄柏、桂枝和桑枝进行定性鉴别,以干膏量和龙胆苦苷含量为指标,采用高效液相色谱法测定含量,运用正交试验法对水提的工艺条件进行优化。结果水提取最佳工艺为:第一次补足吸水量后加10倍量水浸泡0.5 h,其余每次加10倍量水,提取3次,每次提取1 h。结论优选的工艺稳定、可行。
        Objective To optimize the water extraction conditions of Rebikang capsule. Methods An extraction procedure was optimizedby orthogonal test. The content of rutin which was used as the assessment index was determined by HPLC. Results The optimalwater extraction process was as follows: using crude drugs in processed pieces with 10 times water, soak for 2 h, extraction3 times and each time lasts 1 h. Conclusion The optimal process is stable and feasible.

引文

[1]南京中医药大学.中药大辞典[M].上海:上海科学技术出版社,2006.
    [2]宋小妹.中药化学成分提取分离与制备[M].北京:人民卫生出版社,2004:31-36.
    [3]刘定远.医药数理统计学[M].北京:人民卫生出版社,2006:170-180.