原发性IgA肾病病因病机探析
摘要
<正>IgA肾病(IgAN)是我国最常见的慢性肾脏病和终末期肾病的主要原发病。IgA肾病分为原发性和继发性,原发性IgA肾病是最常见的原发性肾小球疾病,是肾脏本身的疾病,占我国原发性肾小球疾病的35%～55%。在很长一段时期,IgA肾病曾被认为是预后良好的疾病,经过30多年的研究,IgA肾病已被发现呈慢性进行性发展,预后并不乐观,每10年有5%～25%患者在IgA肾病诊断确定后进入
引文
1中国中西医结合学会肾脏疾病专业委员会.IgA肾病西医诊断和中医辨证分型的实践指南[J].中国中西医结合杂志,2013,33(5):583-585
2 Xie Y,Chen X.Epidemiology,major outcomes,risk factors,prevention and management of chronic kidney disease in China[J].American Journal of Nephrology,2008,28(1):1-7
3 王少华,卢志远,张红霞,等.IgA肾病病因病机探析[J].吉林中医药,2012,32(7):652-653
4 聂莉芳,徐建龙,余仁欢,等.IgA肾病中医临床实践指南概览[J].中国中西医结合肾病杂志,2013,14(7):565-567
5 张小攀.IgA肾病发病机制的研究新进展[J].国际泌尿系统杂志,2016,36(1):157-162
6 Lemley KV.Podocyt openi a and disease severity in IgA nephropathy[J].Kidney International,2002,61(4):1475-1485
7 Macconi D,Bonomelli M,Benigni A,et al.Pathophysiologic implications of reduced podocyte number in a rat model of progressive glomerular injury[J].American Journal of Pathology,2006,168(1):42-54
8 曾海江,李静,黄郁波.环孢素A治疗难治性肾病综合征的临床观察[J].中国医学创新,2014,17(19):70-72
9 陈香美,谢院生.IgA肾病的发病与治疗[J].中国中西医结合肾病杂志,2006,7(12):683-686
10 Lim CS,Kim SM,Oh YK,et al. Megsin 2093T-2180C haplotype at the 3'untranslated region is associated with poor renal survival in Korean IgA nephropathy patients[J].Clinical Nephrology,2008,70(2):101-109
2 Xie Y,Chen X.Epidemiology,major outcomes,risk factors,prevention and management of chronic kidney disease in China[J].American Journal of Nephrology,2008,28(1):1-7
3 王少华,卢志远,张红霞,等.IgA肾病病因病机探析[J].吉林中医药,2012,32(7):652-653
4 聂莉芳,徐建龙,余仁欢,等.IgA肾病中医临床实践指南概览[J].中国中西医结合肾病杂志,2013,14(7):565-567
5 张小攀.IgA肾病发病机制的研究新进展[J].国际泌尿系统杂志,2016,36(1):157-162
6 Lemley KV.Podocyt openi a and disease severity in IgA nephropathy[J].Kidney International,2002,61(4):1475-1485
7 Macconi D,Bonomelli M,Benigni A,et al.Pathophysiologic implications of reduced podocyte number in a rat model of progressive glomerular injury[J].American Journal of Pathology,2006,168(1):42-54
8 曾海江,李静,黄郁波.环孢素A治疗难治性肾病综合征的临床观察[J].中国医学创新,2014,17(19):70-72
9 陈香美,谢院生.IgA肾病的发病与治疗[J].中国中西医结合肾病杂志,2006,7(12):683-686
10 Lim CS,Kim SM,Oh YK,et al. Megsin 2093T-2180C haplotype at the 3'untranslated region is associated with poor renal survival in Korean IgA nephropathy patients[J].Clinical Nephrology,2008,70(2):101-109