铝碳酸镁对幽门螺杆菌感染活动性胃溃疡患者组织学溃疡愈合质量的影响探析
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摘要
目的:对幽门螺杆菌感染活动性胃溃疡患者应用铝碳酸镁进行合理治疗,观察该药对于患者组织学溃疡愈合质量的影响。方法:收治符合本次研究要求的幽门螺杆菌感染活动性胃溃疡患者86例,按照入院顺序将患者分为观察组和对照组,每组43例。应用三联法对对照组患者进行治疗,观察组患者以此为治疗基础,加用铝碳酸镁进行治疗,对两组患者的临床治疗效果进行对比。结果:治疗过程结束后,观察组患者临床治疗有效率(88.37%)明显优于对照组(69.77%)(P<0.05);观察组患者幽门螺杆菌根除率为69.77%,效果明显优于对照组的48.84%(P<0.05)。结论:对于幽门螺杆菌感染活动性胃溃疡应用铝碳酸镁进行治疗疗效显著,能极大的提升治疗有效率和治疗安全性,具有良好的幽门螺杆菌根除效果。
Objective: To treat the active gastric ulcer patients induced by Helicobacter pylori infection with Hydrotalcite,and to observe its effects of on the healing quality of the patients. Methods: 86 cases of H.pylori-infected patients with active gastric ulcer,who met the requirements of this study,were enrolled. These patients were divided into observation group and control group according to the admission order,43 cases in each group. All the patients were treated with the triple therapy. Besides,the observation group was given Hydrotalcite. The clinical effects of the two groups were compared. Results: The effective rate in the observation group( 88.37%) was significantly better than that in the control group( 69.77%) after the treatment was completed( P<0.05). The efficacy of H.pylori eradication in the observation group( 69. 77%) was significantly better than that of the control group( 48. 84%)( P < 0. 05).Conclusions: Hydrotalcite in the treatment of the patients with active gastric ulcer caused by Helicobacter pylori has significant curative effects,can greatly improve the treatment efficiency and treatment safety,and has good effects of eradication of Helicobacter pylori.
Objective: To treat the active gastric ulcer patients induced by Helicobacter pylori infection with Hydrotalcite,and to observe its effects of on the healing quality of the patients. Methods: 86 cases of H.pylori-infected patients with active gastric ulcer,who met the requirements of this study,were enrolled. These patients were divided into observation group and control group according to the admission order,43 cases in each group. All the patients were treated with the triple therapy. Besides,the observation group was given Hydrotalcite. The clinical effects of the two groups were compared. Results: The effective rate in the observation group( 88.37%) was significantly better than that in the control group( 69.77%) after the treatment was completed( P<0.05). The efficacy of H.pylori eradication in the observation group( 69. 77%) was significantly better than that of the control group( 48. 84%)( P < 0. 05).Conclusions: Hydrotalcite in the treatment of the patients with active gastric ulcer caused by Helicobacter pylori has significant curative effects,can greatly improve the treatment efficiency and treatment safety,and has good effects of eradication of Helicobacter pylori.
引文
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[8]马可可,王洪涛,刘义宾.铝碳酸镁对幽门螺杆菌感染性胃溃疡溃疡愈合质量的影响[J].安徽医药,2016,20(6):1197-1199.
[9]王华敏.雷贝拉唑对幽门螺杆菌感染活动性胃溃疡患者组织学溃疡愈合质量的影响[J].河南医学研究,2017,26(6):1082-1083.
[2]杜志娜,尉迟敏,曲韬.泮托拉唑四联疗法加用胃黏膜保护剂对幽门螺杆菌阳性胃溃疡患者愈合质量的影响[J].实用医院临床杂志,2017,14(3):112-114.
[3]秦浩,隋建超,张树芬,等.雷贝拉唑对成人活动期胃溃疡患者的疗效及溃疡愈合质量的影响[J].国际医药卫生导报,2016,22(13):1948-1952.
[4]赖人旭,任江南,苟新敏,等.铝碳酸镁片联合埃索美拉唑肠溶片治疗幽门螺杆菌感染合并活动性胃溃疡的临床研究[J].中国临床药理学杂志,2017,33(19):1868-1870.
[5]任建刚,贾道全.铝碳酸镁联合兰索拉唑治疗幽门螺旋杆菌相关性胃溃疡的临床疗效及安全性[J].临床和实验医学杂志,2015,21(9):767-769.
[6]白盛慧.铝碳酸镁对幽门螺杆菌感染活动性胃溃疡患者组织学溃疡愈合质量的影响探析[J].当代医学,2017,23(31):108-110.
[7]杨百胜.铝碳酸镁对幽门螺杆菌感染活动性胃溃疡患者组织学溃疡愈合质量的影响探析[J].中国社区医师,2017,33(19):80-81.
[8]马可可,王洪涛,刘义宾.铝碳酸镁对幽门螺杆菌感染性胃溃疡溃疡愈合质量的影响[J].安徽医药,2016,20(6):1197-1199.
[9]王华敏.雷贝拉唑对幽门螺杆菌感染活动性胃溃疡患者组织学溃疡愈合质量的影响[J].河南医学研究,2017,26(6):1082-1083.