慢性心力衰竭患者长期口服托拉塞米对电解质紊乱的影响
|
摘要
目的:总结分析长期口服托拉塞米治疗慢性心力衰竭对患者电解质紊乱的影响。方法:本文确定的研究对象为笔者所在医院2013年8月-2017年4月收治的100例慢性心力衰竭患者,经患者同意后采取抽签方式分为观察组与对照组,各50例,对照组采用呋塞米治疗,观察组采用托拉塞米治疗,对比两组患者临床治疗效果的相关资料。结果:(1)观察组治疗总有效率较对照组更高,差异有统计学意义(P<0.05);(2)在治疗后的血钾、血钠及尿量等水平方面,观察组优于对照组,差异有统计学意义(P<0.05);(3)在治疗期间的毒副作用方面,观察组与对照组之间差异无统计学意义(P>0.05)。结论:慢性心力衰竭患者长期口服托拉塞米能够有效改善电解质紊乱,提高患者治疗效果,且毒副作用不明显,值得推广应用。
Objective:To summarize and analyze the effect of long-term oral Torasemide on electrolyte disturbance in patients with chronic heart failure.Method:100 patients with chronic heart failure were treated in our hospital from August 2013 to April 2017.50 patients were treated with Furosemide in the control group and 50 were treated with Torasemide in the observation group.The treatment effect in two groups was compared.Result:(1)The total efficiency of treatment in observation group was higher than that in control group,and the difference was statistically significant(P<0.05).(2)The observation group was superior to the control group in the levels of potassium,sodium and urine after treatment,and the differences were statistically significant(P<0.05).(3)There was no significant difference between the observation group and the control group in terms of toxic side effects during treatment,which was not statistically significant(P>0.05). Conclusion:Long-term administration of Torasemide in patients with chronic heart failure can effectively improve the electrolyte disorder,improve the efficacy of treatment,and the toxic side effects are not obvious.
Objective:To summarize and analyze the effect of long-term oral Torasemide on electrolyte disturbance in patients with chronic heart failure.Method:100 patients with chronic heart failure were treated in our hospital from August 2013 to April 2017.50 patients were treated with Furosemide in the control group and 50 were treated with Torasemide in the observation group.The treatment effect in two groups was compared.Result:(1)The total efficiency of treatment in observation group was higher than that in control group,and the difference was statistically significant(P<0.05).(2)The observation group was superior to the control group in the levels of potassium,sodium and urine after treatment,and the differences were statistically significant(P<0.05).(3)There was no significant difference between the observation group and the control group in terms of toxic side effects during treatment,which was not statistically significant(P>0.05). Conclusion:Long-term administration of Torasemide in patients with chronic heart failure can effectively improve the electrolyte disorder,improve the efficacy of treatment,and the toxic side effects are not obvious.
引文
[1]焦永学.呋塞米与托拉塞米对慢性心力衰竭治疗效果对比分析[J].世界最新医学信息文摘,2017,17(84):56-59.
[2]管有洪,吕俊廷,容永怡,等.托拉塞米对慢性心力衰竭心功能Ⅲ~Ⅳ级患者预后的影响[J].中国现代药物应用,2017,11(4):27-29.
[3]张创良,龙登毅,李光杰,等.小剂量多巴胺联合托拉塞米治疗老年慢性心力衰竭的疗效[J].中国老年学杂志,2016,36(21):5271-5272.
[4]刘辉,王学惠,张永春,等.托拉塞米治疗慢性心力衰竭的临床观察[J].中国药房,2016,27(29):4093-4095.
[5]肖南海,林创明,康峰光,等.托拉塞米注射液治疗慢性心力衰竭急性加重期的疗效分析[J].吉林医学,2016,37(4):779-781.
[6] Sedlar Natasa,Lainscak Mitja,M?rtensson Jan,et al.Factors related to self-care behaviours in heart failure:A systematic review of European Heart Failure Self-Care Behaviour Scale studies[J].European Journal of Cardiovascular Nursing:Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology,2017,16(4):272-282.
[7] Dubin Ruth F,Deo Rajat,Bansal Nisha,et al.Associations of Conventional Echocardiographic Measures with Incident Heart Failure and Mortality:The Chronic Renal Insufficiency Cohort[J].Clinical Journal of the American Society of Nephrology:CJASN,2017,12(1):60-68.
[8] Huang Weijian,Su Lan,Wu Shengjie,et al.Benefits of Permanent His Bundle Pacing Combined With Atrioventricular Node Ablation in Atrial Fibrillation Patients With Heart Failure With Both Preserved and Reduced Left Ventricular Ejection Fraction[J].Journal of the American Heart Association,2017,6(4):263-270.
[9]黄志敏,庞国珍.托拉塞米与呋塞米治疗儿童肾病综合征伴高度水肿的疗效评价[J].儿科药学杂志,2017,23(5):12-14.
[10]张春红.综合护理对老慢支肺气肿患者不良情绪及睡眠质量的改善作用[J].中国老年保健医学,2016,14(6):106-107.
[11]黄绍精,曲军,陈新.托拉塞米与呋塞米治疗急性脑出血后脑水肿疗效[J].宁夏医科大学学报,2016,38(7):807-810.
[12]杜金勇,王功勋.托拉塞米序贯治疗对冠心病致慢性心衰心功能的影响[J].现代临床医学,2016,42(1):31-33.
[13]黄晓蓉.慢支肺气肿合并肺炎的X线临床诊断分析[J].大家健康:学术版,2015,9(11):34.
[14]孙永全,李淑萍.托拉塞米和呋塞米治疗脑出血并急性脑水肿的疗效比较[J].中国实用神经疾病杂志,2015,18(1):113-115.
[2]管有洪,吕俊廷,容永怡,等.托拉塞米对慢性心力衰竭心功能Ⅲ~Ⅳ级患者预后的影响[J].中国现代药物应用,2017,11(4):27-29.
[3]张创良,龙登毅,李光杰,等.小剂量多巴胺联合托拉塞米治疗老年慢性心力衰竭的疗效[J].中国老年学杂志,2016,36(21):5271-5272.
[4]刘辉,王学惠,张永春,等.托拉塞米治疗慢性心力衰竭的临床观察[J].中国药房,2016,27(29):4093-4095.
[5]肖南海,林创明,康峰光,等.托拉塞米注射液治疗慢性心力衰竭急性加重期的疗效分析[J].吉林医学,2016,37(4):779-781.
[6] Sedlar Natasa,Lainscak Mitja,M?rtensson Jan,et al.Factors related to self-care behaviours in heart failure:A systematic review of European Heart Failure Self-Care Behaviour Scale studies[J].European Journal of Cardiovascular Nursing:Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology,2017,16(4):272-282.
[7] Dubin Ruth F,Deo Rajat,Bansal Nisha,et al.Associations of Conventional Echocardiographic Measures with Incident Heart Failure and Mortality:The Chronic Renal Insufficiency Cohort[J].Clinical Journal of the American Society of Nephrology:CJASN,2017,12(1):60-68.
[8] Huang Weijian,Su Lan,Wu Shengjie,et al.Benefits of Permanent His Bundle Pacing Combined With Atrioventricular Node Ablation in Atrial Fibrillation Patients With Heart Failure With Both Preserved and Reduced Left Ventricular Ejection Fraction[J].Journal of the American Heart Association,2017,6(4):263-270.
[9]黄志敏,庞国珍.托拉塞米与呋塞米治疗儿童肾病综合征伴高度水肿的疗效评价[J].儿科药学杂志,2017,23(5):12-14.
[10]张春红.综合护理对老慢支肺气肿患者不良情绪及睡眠质量的改善作用[J].中国老年保健医学,2016,14(6):106-107.
[11]黄绍精,曲军,陈新.托拉塞米与呋塞米治疗急性脑出血后脑水肿疗效[J].宁夏医科大学学报,2016,38(7):807-810.
[12]杜金勇,王功勋.托拉塞米序贯治疗对冠心病致慢性心衰心功能的影响[J].现代临床医学,2016,42(1):31-33.
[13]黄晓蓉.慢支肺气肿合并肺炎的X线临床诊断分析[J].大家健康:学术版,2015,9(11):34.
[14]孙永全,李淑萍.托拉塞米和呋塞米治疗脑出血并急性脑水肿的疗效比较[J].中国实用神经疾病杂志,2015,18(1):113-115.