芪苈强心胶囊治疗对老年慢性心力衰竭患者脑钠肽水平及预后的影响
|
摘要
目的探讨芪苈强心胶囊治疗对老年慢性心力衰竭患者脑钠肽(BNP)水平及预后的影响。方法选取86例老年慢性心力衰竭患者按随机数字表法分为观察组与对照组,各43例,对照组予以西医常规治疗,观察组在此基础上联合芪苈强心胶囊治疗,比较2组治疗效果。结果观察组治疗后的左心室射血分数(LVEF)、6min步行试验(6MWT)显著高于对照组,左心室舒张末期内径(LVEDD)显著低于对照组,差异具有统计学意义(P<0.05)。观察组治疗后的心肌营养素(CT-1)、丙二醛(MDA)、BNP显著低于对照组,差异具有统计学意义(P<0.05)。观察组治疗后的生活质量评分显著高于对照组,差异具有统计学意义(P<0.05)。结论芪苈强心胶囊治疗老年慢性心力衰竭的疗效良好,值得推荐。
Objective To investigate the effect of Qiliqiangxin capsule on BNP level in elderly patients with chronic heart failure.Methods Eighty-six elderly patients with chronic heart failure were divided into observation group and control group.The control group were given conventional western medicine treatment,while the observation group were treated with Qiliqiangxin capsule.The therapeutic effects of 2 groups were compared.ResultsThe scores of LVEF,6 MWT and quality of life in the observation group were significantly higher than those in the control group,while LVEDD,CT-1,MDA and BNP were significantly lower than those in the control group,the difference was statistically significant(P <0.05).Conclusion Qiliqiangxin capsule is effective in the treatment of elderly patients with chronic heart failure.
Objective To investigate the effect of Qiliqiangxin capsule on BNP level in elderly patients with chronic heart failure.Methods Eighty-six elderly patients with chronic heart failure were divided into observation group and control group.The control group were given conventional western medicine treatment,while the observation group were treated with Qiliqiangxin capsule.The therapeutic effects of 2 groups were compared.ResultsThe scores of LVEF,6 MWT and quality of life in the observation group were significantly higher than those in the control group,while LVEDD,CT-1,MDA and BNP were significantly lower than those in the control group,the difference was statistically significant(P <0.05).Conclusion Qiliqiangxin capsule is effective in the treatment of elderly patients with chronic heart failure.
引文
[1]李超,朱余兵,石婷.慢性心力衰竭患者采用稳心颗粒与美托洛尔联合治疗的效果及对心功能血管内皮功能的影响[J].山西医药杂志,2017,46(20):2418-2421.
[2]张洪,薛蕾.芪苈强心胶囊治疗舒张性心衰的临床应用效果分析[J].北方药学,2018,15(3):17-18.
[3]方如民.重组人脑利钠肽治疗急性心肌梗死后心力衰竭临床疗效及对内皮功能和炎症因子的影响[J].山西医药杂志,2017,46(4):378-380.
[4]胡霜,蔡莉,张川平.美托洛尔联合芪苈强心胶囊治疗慢性心力衰竭的疗效观察[J].重庆医学,2017,46(5):689-691.
[5]葛均波,徐永健.内科学[M].8版.北京:人民卫生出版社,2013:174-175.
[6]袁逾喆,王志甫,冯柯.曲美他嗪联合芪苈强心胶囊对慢性心力衰竭患者血清Gal-3、Copeptin水平变化及生活质量的影响[J].中国合理用药探索,2018,15(4):49-51,59.
[7]殷国田,解娜,黄艳梅,等.芪苈强心胶囊联合辅酶Q10对老年高血压并心衰患者心肌营养素-1、丙二醛水平的影响[J].中国老年学杂志,2017,37(9):2149-2151.
[8]张大程,张春雨,鹿梦溪.芪苈强心胶囊联合西药常规对慢性心力衰竭患者心室重构及相关免疫指标的影响[J].河北医药,2017,39(21):3209-3212.
[2]张洪,薛蕾.芪苈强心胶囊治疗舒张性心衰的临床应用效果分析[J].北方药学,2018,15(3):17-18.
[3]方如民.重组人脑利钠肽治疗急性心肌梗死后心力衰竭临床疗效及对内皮功能和炎症因子的影响[J].山西医药杂志,2017,46(4):378-380.
[4]胡霜,蔡莉,张川平.美托洛尔联合芪苈强心胶囊治疗慢性心力衰竭的疗效观察[J].重庆医学,2017,46(5):689-691.
[5]葛均波,徐永健.内科学[M].8版.北京:人民卫生出版社,2013:174-175.
[6]袁逾喆,王志甫,冯柯.曲美他嗪联合芪苈强心胶囊对慢性心力衰竭患者血清Gal-3、Copeptin水平变化及生活质量的影响[J].中国合理用药探索,2018,15(4):49-51,59.
[7]殷国田,解娜,黄艳梅,等.芪苈强心胶囊联合辅酶Q10对老年高血压并心衰患者心肌营养素-1、丙二醛水平的影响[J].中国老年学杂志,2017,37(9):2149-2151.
[8]张大程,张春雨,鹿梦溪.芪苈强心胶囊联合西药常规对慢性心力衰竭患者心室重构及相关免疫指标的影响[J].河北医药,2017,39(21):3209-3212.