数字X射线骨密度检测系统前臂桡骨测量结果的评估
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摘要
目的对比研究数字X射线骨密度检测系统和双能X线吸收检测法(dual-energy X-ray absorptiometry,DXA)检测桡骨骨密度(bone mineral density,BMD)两种不同测量方法的精确性和准确性。方法在浙江省人民医院用数字X射线骨密度检测系统及DXA对34名受试者的桡骨远端1/3处各测量2次,并对两种不同测量方法的精确性、准确性进行统计学分析。结果本研究中的34名受试者年龄31～81岁,平均年龄(55. 0±13. 3)岁,采用数字X射线骨密度检测系统测量的均方误差及均方变异系数分别为(0. 015 g/cm~2及1. 7%),均小于DXA的测量结果 (0. 019 g/cm~2及2. 1%)。两种检测方法检测的BMD值之间差异无统计学意义(P>0. 05)。结论数字X射线骨密度检测系统测量同DXA测量结果相似,可用于临床前臂桡骨骨密度测量和评估。
Objective To compare the precision of radius bone mineral density( BMD) measurement using digital X-ray densitometry with that using dual-energy X-ray absorptiometry( DXA). Methods Thirty-four volunteers' forearm BMDs were measured with both digital X-ray densitometry and DXA. To evaluate the measurement precision,scanning was performed twice by both machines for each subject. Results The average age of volunteers is( 55. 0± 13. 3) years old( 31-81) years old,root-mean-square( RMS) standard deviation( RMS-SD) and DMS-coefficient of variation( RMS-CV) of BMD measured by digital X-ray densitometry were 0. 015 g/cm~2 and 1. 7%,which were smaller than0. 019 g/cm~2 and 2. 1% measured by DXA). Furthermore,there is no significant difference between BMD measured by these two techniques. Conclusion Forearm BMD measurement using digital X-ray densitometry is similar to DXA thus digital X-ray densitomeny could be used for forearm BMD evaluation.
Objective To compare the precision of radius bone mineral density( BMD) measurement using digital X-ray densitometry with that using dual-energy X-ray absorptiometry( DXA). Methods Thirty-four volunteers' forearm BMDs were measured with both digital X-ray densitometry and DXA. To evaluate the measurement precision,scanning was performed twice by both machines for each subject. Results The average age of volunteers is( 55. 0± 13. 3) years old( 31-81) years old,root-mean-square( RMS) standard deviation( RMS-SD) and DMS-coefficient of variation( RMS-CV) of BMD measured by digital X-ray densitometry were 0. 015 g/cm~2 and 1. 7%,which were smaller than0. 019 g/cm~2 and 2. 1% measured by DXA). Furthermore,there is no significant difference between BMD measured by these two techniques. Conclusion Forearm BMD measurement using digital X-ray densitometry is similar to DXA thus digital X-ray densitomeny could be used for forearm BMD evaluation.
引文
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[14]陈建锋,范运洲,李鹏,等.智能放射吸收法的临床应用—人体手臂骨骨密度的测量及其骨质疏松的评估[J].中国医疗设备,2018,33:31-35.
[15]余卫,林强,于晓波,等.双能X线骨密度仪i DXA机型测量的精确性评估[J].中华放射学杂志,2009,12:1291-1294.
[16] Pearson D,Horton B,Green DJ. Cross calibration of Hologic QDR2000 and GE Lunar Prodigy for forearm bone mineral density measurements[J]. J Clin Densitom,2007,10:306-311.
[17] Chang YJ,Yu W,Lin Q,et al. Forearm bone mineral density measurement with different scanning positions:a study in right-handed Chinese using dual-energy Xray absorptiometry[J]. J Clin Densitom,2012,15:67-71.
[2] Baim S,Wilson C,Lewiecki EM,et al. Precision assessment and radiation safety for dual-energy X-ray absorptiometry:position paper of the International Society for Clinical Densitometry[J]. J Clin Densitom,2006,8:371-378.
[3] World Health Organization. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis[R]. Geneva:WHO,1994.
[4] Baim S,Binkley N,Bilezikian JP,et al. Official Positions of the International Society for Clinical Densitometry and executive summary of the 2007 ISCD Position Development Conference[J]. J Clin Densitom,2001,4:105-110.
[5] Miller PD,Siris ES,Barrett-Connor E,et al. Prediction of fracture risk in postmenopausal white women with peripheral bone densitometry:evidence from the National Osteoporosis Risk Assessment[J]. J Bone Miner Res,2002,17:2222-2230.
[6] Greenspan S,Maitland-Ramsey L,Myers E. Classification of osteoporosis in the elderly is dependent on site-specific analysis[J]. Calcif Tissue Int,1996,58:409-414.
[7] Weinstein M,Fineberg H. Clinical decision analysis[M]. Philadelphia:W. B. Saunders Company,1980:131-167.
[8] Bonnick SL,Johnston CC Jr,Kleerekoper M,et al.Importance of precision in bone density measurements[J]. J Clin Densitom,2001,4:105-110.
[9] Faulkner KG,McClung MR. Quality control of DXA instruments in multicenter trials[J]. Osteoporos Int,1995,5:218-227.
[10] Glüer CC,Faulkner KG,Estilo MJ,et al. Quality assurance for bone densitometry research studies:concept and impact[J]. Osteoporos Int,1993,3:227-235.
[11] Miller CG. Bone density measurements in clinical trials:the challenge of ensuring optimal data[J]. Br J Clin Res,1993,4:113-220.
[12] Forsén L,Berntsen GK,Meyer HE,et al. Differences in precision in bone mineral density measured by SXA and DXA:the NOREPOS study[J]. Eur J Epidemiol,2008,23:615-624.
[13] Augat P,Fuerst T,Genant HK. Quantitative bone mineral assessment at the forearm:a review[J]. Osteoporos Int,1998,8:299-310.
[14]陈建锋,范运洲,李鹏,等.智能放射吸收法的临床应用—人体手臂骨骨密度的测量及其骨质疏松的评估[J].中国医疗设备,2018,33:31-35.
[15]余卫,林强,于晓波,等.双能X线骨密度仪i DXA机型测量的精确性评估[J].中华放射学杂志,2009,12:1291-1294.
[16] Pearson D,Horton B,Green DJ. Cross calibration of Hologic QDR2000 and GE Lunar Prodigy for forearm bone mineral density measurements[J]. J Clin Densitom,2007,10:306-311.
[17] Chang YJ,Yu W,Lin Q,et al. Forearm bone mineral density measurement with different scanning positions:a study in right-handed Chinese using dual-energy Xray absorptiometry[J]. J Clin Densitom,2012,15:67-71.