乳铁蛋白分离纯化研究进展
|
摘要
乳铁蛋白是一种非血红素转铁蛋白,与血清转铁蛋白、卵转铁蛋白和黑素转铁蛋白共同组成转铁蛋白家族。乳铁蛋白是一种多功能性的糖蛋白,具有很多的活性,被广泛应用于保健食品、配方奶粉、医药等领域中。归纳传统的与新开发的乳铁蛋白的回收方法,比较每种方法在提取回收乳铁蛋白中的优势与不足,对今后开发出更佳具有优势的乳铁蛋白的回收方法提供一些思路。
Lactoferrin is a non-heme transferrin,which is composed of the transferrin family with serum transferrin,egg transferrin and melanin transferrin. Due to lactoferrin is a glycoprotein with pleiotropic activities,it has been widely used in health food,infant formula,medicine and other areas. Statement of traditional and new development of lactoferrin recycling methods,the advantages and disadvantages of each method was compared. It provided some ideas for the development of better methods for the recovery of lactoferrin with advantages in the future.
Lactoferrin is a non-heme transferrin,which is composed of the transferrin family with serum transferrin,egg transferrin and melanin transferrin. Due to lactoferrin is a glycoprotein with pleiotropic activities,it has been widely used in health food,infant formula,medicine and other areas. Statement of traditional and new development of lactoferrin recycling methods,the advantages and disadvantages of each method was compared. It provided some ideas for the development of better methods for the recovery of lactoferrin with advantages in the future.
引文
[1]Jillian Cornish,Karen E Callon,Dorit Naot,et al.Lactoferrin Is a Potent Regulator of Bone Cell Activity and Increases Bone Formation in Vivo[J].Endocrinology,2003,145(9):4366-4374
[2]Sivaraman Arumugam Balasubramanian,David Cecil Pye,Mark Duncan Perry Willcox.Levels of lactoferrin,secretory IgA and serum albumin in the tear film of people with keratoconus[J].Experimental Eye Research,2012,96(1):132-137
[3]Mamoru Tomita,Hiroyuki Wakabayashi,Kouichirou Shin,et al.Twenty-five years of research on bovine lactoferrin applications[J].Biochimie,2009,91(1):52-57
[4]Conan J Fee,Amita Chand.Capture of lactoferrin and lactoperoxidase from raw whole milk by cation exchange chromatography[J].Separation and Purification Technology,2006,48(2):143-149
[5]Kerstin Plate,Sascha Beutel,Heinrich Buchholz,et al.Isolation of bovine lactoferrin,lactoperoxidase and enzymatically prepared lactoferricin from proteolytic digestion of bovine lactoferrin using adsorptive membrane chromatography[J].Journal of Chromatography A,2006,1117(1):81-86
[6]Linda Voswinkel,Thomas Vogel,Ulrich Kulozik.Impact of the iron saturation of bovine lactoferrin on adsoprtion to a strong cation exchanger membrane[J].International Dairy Journal,2016,56(2):134-140
[7]Rong Rong Lu,Shi Ying Xu,Zhang Wang,et al.Isolation of lactoferrin from bovine colostrum by ultrafiltration coupled with strong cation exchange chromatography on a production scale[J].Journal of Membrane Science,2007,297:152-161
[8]M C Almécija,R Ibáez A,Guadix E M.Guadix.Influence of p H in the recovery of lactoferrin from whey with ceramic membranes[J].Desalination,2006,200(1):475-476
[9]G Brisson,M Britten,Y Pouliot.Electrically-enhanced crossflow microfiltration for separation of lactoferrin from whey protein mixtures[J].Journal of Membrane Science,2007,297(2):206-216
[10]Elisabeth Fuda,Paula Jauregi,D L Pyle.Recovery of Lactoferrin and Lactoperoxidase from Sweet Whey Using Colloidal Gas Aphrons(CGAs)Generated from an Anionic Surfactant,AOT[J].Biotechnology Progress,2004,20(2):514-525
[11]Jonatan Andersson,Bo Mattiasson.Simulated moving bed technology with a simplified approach for protein purification Separation of lactoperoxidase and lactoferrin from whey protein concentrate[J].Journal of Chromatography A,2006,1107(2):88-95
[12]N Ndiaye,Y Pouliot,L Saucier,et al.Electroseparation of bovine lactoferrin from model and whey solutions[J].Separation and Purification Technology,2010,74(1):93-99
[13]Shun Yamaguchi,Takayuki Miura,Asami Baba,et al.Separation of a milk acid phosphatase from a purified lactoferrin fraction and identification as a member of the mammalian purple acid phosphatase family[J].International Dairy Journal,2012,23(2):86-90
[14]Paul K Ng,Tomohiko Yoshitake.Purification of lactoferrin using hydroxyapatite[J].Journal of Chromatography B,2010,878(14):976-980
[15]Wim Noppe,Fatima M Plieva,Igor Yu Galaev,et al.Immobilised peptide displaying phages as affinity ligands purification of lactoferrin from defatted milk[J].Journal of Chromatography A,2006,1101(1):79-85
[16]Bo-Hung Lai,Chih-Hao Chang,Chun-Chieh Yeh,et al.Direct binding of Concanvalin A onto iron oxide nanoparticles for fast magnetic selective separation of lactoferrin[J].Separation and Purification Technology,2013,108:83-88
[17]Lin Chen,Chen Guo,Yueping Guan,et al.Isolation of lactoferrin from acid whey by magnetic affinity separation[J].Separation and Purification Technology,2007,56(2):168-174
[18]Enrique Alvarez-Guerra,Angel Irabien.Extraction of lactoferrin with hydrophobic ionic liquids[J].Separation and Purification Technology,2012,98(39):432-440
[19]Mian-bin Wu,Yin-jun Xu.Isolation and Purification of Lactoferrin and Immunoglobulin G from Bovine Colostrum with Serial CationAnion Exchange Chromatography[J].Biotechnology and Bioprocess Engineering,2009,14(2):155-160
[20]Syed M Saufi,Conan J Fee.Recovery of lactoferrin from whey using cross-flow cation exchange mixed matrix membrane chromatography[J].Separation and Purification Technology,2011,77(1):68-75
[21]V Orr,L Zhong,M Moo-Young,et al.Recent advances in bioprocessing application of membrane chromatography[J].Biotechnology Advances,2013,31(4):450-465
[2]Sivaraman Arumugam Balasubramanian,David Cecil Pye,Mark Duncan Perry Willcox.Levels of lactoferrin,secretory IgA and serum albumin in the tear film of people with keratoconus[J].Experimental Eye Research,2012,96(1):132-137
[3]Mamoru Tomita,Hiroyuki Wakabayashi,Kouichirou Shin,et al.Twenty-five years of research on bovine lactoferrin applications[J].Biochimie,2009,91(1):52-57
[4]Conan J Fee,Amita Chand.Capture of lactoferrin and lactoperoxidase from raw whole milk by cation exchange chromatography[J].Separation and Purification Technology,2006,48(2):143-149
[5]Kerstin Plate,Sascha Beutel,Heinrich Buchholz,et al.Isolation of bovine lactoferrin,lactoperoxidase and enzymatically prepared lactoferricin from proteolytic digestion of bovine lactoferrin using adsorptive membrane chromatography[J].Journal of Chromatography A,2006,1117(1):81-86
[6]Linda Voswinkel,Thomas Vogel,Ulrich Kulozik.Impact of the iron saturation of bovine lactoferrin on adsoprtion to a strong cation exchanger membrane[J].International Dairy Journal,2016,56(2):134-140
[7]Rong Rong Lu,Shi Ying Xu,Zhang Wang,et al.Isolation of lactoferrin from bovine colostrum by ultrafiltration coupled with strong cation exchange chromatography on a production scale[J].Journal of Membrane Science,2007,297:152-161
[8]M C Almécija,R Ibáez A,Guadix E M.Guadix.Influence of p H in the recovery of lactoferrin from whey with ceramic membranes[J].Desalination,2006,200(1):475-476
[9]G Brisson,M Britten,Y Pouliot.Electrically-enhanced crossflow microfiltration for separation of lactoferrin from whey protein mixtures[J].Journal of Membrane Science,2007,297(2):206-216
[10]Elisabeth Fuda,Paula Jauregi,D L Pyle.Recovery of Lactoferrin and Lactoperoxidase from Sweet Whey Using Colloidal Gas Aphrons(CGAs)Generated from an Anionic Surfactant,AOT[J].Biotechnology Progress,2004,20(2):514-525
[11]Jonatan Andersson,Bo Mattiasson.Simulated moving bed technology with a simplified approach for protein purification Separation of lactoperoxidase and lactoferrin from whey protein concentrate[J].Journal of Chromatography A,2006,1107(2):88-95
[12]N Ndiaye,Y Pouliot,L Saucier,et al.Electroseparation of bovine lactoferrin from model and whey solutions[J].Separation and Purification Technology,2010,74(1):93-99
[13]Shun Yamaguchi,Takayuki Miura,Asami Baba,et al.Separation of a milk acid phosphatase from a purified lactoferrin fraction and identification as a member of the mammalian purple acid phosphatase family[J].International Dairy Journal,2012,23(2):86-90
[14]Paul K Ng,Tomohiko Yoshitake.Purification of lactoferrin using hydroxyapatite[J].Journal of Chromatography B,2010,878(14):976-980
[15]Wim Noppe,Fatima M Plieva,Igor Yu Galaev,et al.Immobilised peptide displaying phages as affinity ligands purification of lactoferrin from defatted milk[J].Journal of Chromatography A,2006,1101(1):79-85
[16]Bo-Hung Lai,Chih-Hao Chang,Chun-Chieh Yeh,et al.Direct binding of Concanvalin A onto iron oxide nanoparticles for fast magnetic selective separation of lactoferrin[J].Separation and Purification Technology,2013,108:83-88
[17]Lin Chen,Chen Guo,Yueping Guan,et al.Isolation of lactoferrin from acid whey by magnetic affinity separation[J].Separation and Purification Technology,2007,56(2):168-174
[18]Enrique Alvarez-Guerra,Angel Irabien.Extraction of lactoferrin with hydrophobic ionic liquids[J].Separation and Purification Technology,2012,98(39):432-440
[19]Mian-bin Wu,Yin-jun Xu.Isolation and Purification of Lactoferrin and Immunoglobulin G from Bovine Colostrum with Serial CationAnion Exchange Chromatography[J].Biotechnology and Bioprocess Engineering,2009,14(2):155-160
[20]Syed M Saufi,Conan J Fee.Recovery of lactoferrin from whey using cross-flow cation exchange mixed matrix membrane chromatography[J].Separation and Purification Technology,2011,77(1):68-75
[21]V Orr,L Zhong,M Moo-Young,et al.Recent advances in bioprocessing application of membrane chromatography[J].Biotechnology Advances,2013,31(4):450-465