复方肿节风雾化剂联合穴位注射治疗风热型急性咽炎临床研究
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摘要
目的:观察复方肿节风雾化剂雾化吸入联合廉泉、环甲膜、天突穴穴位注射疗法治疗风热型急性咽炎的临床疗效。方法:将90例患者随机分为2组,对照组45例采用炎琥宁注射液予廉泉、环甲膜、天突穴穴位注射,隔天1次;治疗组45例在对照组治疗的基础上予复方肿节风雾化剂雾化吸入,每天1次,2组疗程均为5天;观察治疗前后咽痛、咽干、咽部灼热感、咽部黏膜急性弥漫性充血、咳嗽、咳痰等症状总积分的变化,主次症减轻的时间,并进行临床疗效评价。结果:总有效率治疗组为97.78%,对照组为86.67%,2组比较,差异有统计学意义(P <0.05)。治疗后第1、3天,2组症状总分积比较,差异无统计学意义(P> 0.05);治疗后第5天,治疗组症状总积分明显低于对照组,差异有统计学意义(P <0.05)。治疗后,咽干、咽部灼热缓解时间比较,差异无统计学意义(P> 0.05);而治疗组咽痛缓解时间明显短于对照组,差异有统计学意义(P <0.05)。2组不良反应发生率均为4.44%。结论:复方肿节风雾化剂雾化吸入联合穴位注射治疗风热型急性咽炎疗效显著,且副作用少,值得临床推广应用。
Objective:To observe the clinical effect of the Compound Zhongjiefeng Aerosol Inhalation combined with the point injection at Lianquan(CV23),cricothyroid ligament and Tiantu(CV22) for acute pharyngitis of wind-heat type. Methods:A total of 90 cases of patients were divided into two groups randomly,45 cases in each group. The control group was treated with the point injection of Potassium Sodium Dehydroanrograpolide Succinate Injection at Lianquan(CV23), cricothyroid ligament and Tiantu(CV22) once every two days. The treatment group was additionally treated with the Compound Zhongjiefeng Aerosol Inhalation based on the treatment of the control group once a day. The course of treatment lasted for five days in both groups. The symptoms of pharyngalgia,dry pharynx,burning sensation of pharynx,acute diffuse hyperemia of pharyngeal mucosa,cough,expectoration before and after treatment,the changes of Total symptom score,as well as the remission time of the main and secondary symptoms were observed,and the Clinical efficacy. Results:The total effective rate was 97.78% in the treatment group and 88.89% in the control group,the difference being significant(P < 0.05).There was no significant difference being found in the comparison of the total symptom score between the two groups on the 1st and 3 rd day after treatment(P > 0.05). On the 5th day after treatment,the total symptom score in the treatment group was significantly lower than that in the control group,the difference being significant(P < 0.05). There was no significant difference being found in the comparison of the remission time of dry throat and burning throat between the two groups after treatment(P > 0.05);the remission time of pharyngalgia in the treatment group was significantly shorter than that in the control group,the difference being significant(P < 0.05). The incidence of adverse reactions in both groups were 4.44%.Conclusion:The therapy of the Compound Zhongjiefeng Aerosol Inhalation combined with the point injection therapy has significant therapeutic effect in treat ing acute pharyngitis of wind-heat type,which has few side effects and is worthy of further clinical application.
Objective:To observe the clinical effect of the Compound Zhongjiefeng Aerosol Inhalation combined with the point injection at Lianquan(CV23),cricothyroid ligament and Tiantu(CV22) for acute pharyngitis of wind-heat type. Methods:A total of 90 cases of patients were divided into two groups randomly,45 cases in each group. The control group was treated with the point injection of Potassium Sodium Dehydroanrograpolide Succinate Injection at Lianquan(CV23), cricothyroid ligament and Tiantu(CV22) once every two days. The treatment group was additionally treated with the Compound Zhongjiefeng Aerosol Inhalation based on the treatment of the control group once a day. The course of treatment lasted for five days in both groups. The symptoms of pharyngalgia,dry pharynx,burning sensation of pharynx,acute diffuse hyperemia of pharyngeal mucosa,cough,expectoration before and after treatment,the changes of Total symptom score,as well as the remission time of the main and secondary symptoms were observed,and the Clinical efficacy. Results:The total effective rate was 97.78% in the treatment group and 88.89% in the control group,the difference being significant(P < 0.05).There was no significant difference being found in the comparison of the total symptom score between the two groups on the 1st and 3 rd day after treatment(P > 0.05). On the 5th day after treatment,the total symptom score in the treatment group was significantly lower than that in the control group,the difference being significant(P < 0.05). There was no significant difference being found in the comparison of the remission time of dry throat and burning throat between the two groups after treatment(P > 0.05);the remission time of pharyngalgia in the treatment group was significantly shorter than that in the control group,the difference being significant(P < 0.05). The incidence of adverse reactions in both groups were 4.44%.Conclusion:The therapy of the Compound Zhongjiefeng Aerosol Inhalation combined with the point injection therapy has significant therapeutic effect in treat ing acute pharyngitis of wind-heat type,which has few side effects and is worthy of further clinical application.
引文
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[2]阮岩,王士贞,刘大新.中医耳鼻咽喉科学[M].2版.北京:人民卫生出版社,2016:100-102.
[3]田勇泉,韩东一,迟放鲁,等.耳鼻咽喉头颈外科学[M].8版.北京:人民卫生出版社,2013:128-129.
[4]佚名.急喉痹的诊断依据、证候分类、疗效评定---中华人民共和国中医药行业标准《中医内科病证诊断疗效标准》(ZY/T001.1-94)[J].辽宁中医药大学学报,2018,20(2):59.
[5]Tasar A,Yanturali S,Topacogliu H,et al.Clinical efficacy of dexamethasone for acute exudative aryngitis[J].J Emerg Med,2008,35(4):363-367.
[6]张燕平,韩云霞,欧丽.复方肿节风Ⅰ号雾化剂治疗急性咽炎100例[J].陕西中医,2007,28(8):955-956.