羊肚菌多糖类物质的研究进展
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摘要
羊肚菌是珍稀的药食两用真菌,有极高的营养价值和药用价值。多糖是羊肚菌主要的大分子活性物质,有免疫调节、抗肿瘤、抗氧化和抗衰老等生物活性。本文主要从羊肚菌多糖提取纯化、多糖组成分析、生物活性和构效关系等方面论述羊肚菌多糖。为羊肚菌多糖进一步研究与开发提供理论依据。
Morchella esculenta L. is a rare medicinal and edible fungus with high nutritional value and medicinal value.Polysaccharides are the main macromolecular substance with a wide range of physiological activities. Polysaccharides are the major active substances of most edible fungi which have biological activities such as immune regulation,anti-tumor,antioxidant and anti-aging and so on.This article mainly observed the current researches on Morchella's polysaccharides from respects of compositional analysis of polysaccharides,the extraction and purification of polysaccharides,the biological activities and the structure-activity relationship. This paper mainly provided a theoretical basis for further research and development of the polysaccharides from Morchella esculenta L.
Morchella esculenta L. is a rare medicinal and edible fungus with high nutritional value and medicinal value.Polysaccharides are the main macromolecular substance with a wide range of physiological activities. Polysaccharides are the major active substances of most edible fungi which have biological activities such as immune regulation,anti-tumor,antioxidant and anti-aging and so on.This article mainly observed the current researches on Morchella's polysaccharides from respects of compositional analysis of polysaccharides,the extraction and purification of polysaccharides,the biological activities and the structure-activity relationship. This paper mainly provided a theoretical basis for further research and development of the polysaccharides from Morchella esculenta L.
引文
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[2]权美平,张丽芳.羊肚菌生物学特征及价值的研究进展[J].北方园艺,2012(18):178-180.
[3]顾可飞,刘海燕,杨海峰,等.电子束辐照对羊肚菌营养成份影响分析[J/OL].食品工业科技:1-16[2018-04-05].http://kns.cnki.net/kcms/detail/11.1759.TS.20180111.1659.042.html.
[4]李娟,王臻,姚良同,等.羊肚菌多糖研究进展[J].微生物学杂志,2005,25(4):89-91.
[5]林晓民,李振歧,侯军.中国大型真菌的多样性[M].北京:中国农业出版社,2005.
[6]李文佳,田野,高昊,等.羊肚菌化学成分及药理活性研究进展[J].菌物研究,2017,15(2):144-150.
[7]唐茂芝,贝峰.食用菌类食品作为功能性食品的优势和特点[J].食品科技,1999(3):3-4.
[8]邱博韬,张鸿宇,许志茹,等.多糖分析方法研究进展[J].食品工业科技,2018,39(6):327-333.
[9]刘超.液体深层发酵羊肚菌胞内多糖提取、结构分析及抗结肠癌作用研究[D].长春:吉林大学,2017.
[10]丁健峰.羊肚菌富硒深层发酵工艺及产物功能性研究[D].长春:吉林大学,2014.
[11]熊川,罗强,李强,等.六妹羊肚菌多糖部分理化性质及抗氧化活性研究[J].天然产物研究与开发,2017,29(7):1182-1187,1153.
[12]许晖,孙兰萍,张斌,等.响应面法优化羊肚菌多糖的提取工艺[J].中国酿造,2007(3):44-48.
[13]余梦瑶,许晓燕,江南,等.尖顶羊肚菌菌丝体胞外多糖的分离纯化及结构研究[J].四川大学学报:自然科学版,2013,50(6):1373-1378.
[14]周富川.灰树花多糖降血糖活性及作用机理的研究[D].天津:天津科技大学,2012.
[15]李蔚.液体深层发酵羊肚菌水溶性多糖的提取分离纯化分析[D].乌鲁木齐:新疆农业大学,2008.
[16]郭晓蕾.羊肚菌发酵液及其胞外多糖的分析与研究[D].长春:吉林大学,2016.
[17]Duncan C J,Pugh N,Pasco D S,et al.Isolation of a galactomannan that enhances macrophage activation from the edible fungus Morchella esculenta[J].J Agric Food Chem,2002,50(20):5683-5685.
[18]明建,曾凯芳,赵国华,等.羊肚菌水溶性多糖PMEP-1的分离纯化与结构特征分析[J].食品科学,2009,30(15):104-108.
[19]杨虎.云南野生羊肚菌多糖的分离纯化与性质研究[D].重庆:西南大学,2007.
[20]李敬,周伟杰,赵士豪,等.羊肚菌多糖的分离纯化及其体外抗氧化、抗肿瘤活性研究[J].天然产物研究与开发,2016,28(9):1351-1356.
[21]Liu C,Sun Y,Mao Q,et al.Characteristics and antitumor activity of Morchella esculenta polysaccharide extracted by pulsed electric field[J].International Journal of Molecular Sciences,2016,17(6):986.
[22]张玉,刘超.高压脉冲电场法提取羊肚菌多糖及其分离纯化[J].食品工业,2016,37(12):54-58.
[23]矫丽曼.羊肚菌胞内多糖的提取及单糖组成分析[J].西部林业科学,2016,45(4):130-135.
[24]魏芸,张天佑,张姝,等.羊肚菌多糖的分离纯化及组成结构分析[J].植物资源与环境学报,2000,9(2):14-17.
[25]崔华丽.羊肚菌多糖的结构特点和抗肿瘤机制的研究[D].合肥:安徽大学,2011.
[26]Cui H L,Yan C,Wang S S,et al.Isolation,partial characterisation and immunomodulatory activities of polysaccharide from Morchella esculenta[J].Journal of the Science of Food&Agriculture,2011,91(12):2180.
[27]李飞翔.尖顶羊肚菌菌丝体发酵条件优化及其多糖性质研究[D].昆明:昆明理工大学,2015.
[28]姚珩.羊肚菌发酵豆渣生产多糖的工艺及其性质研究[D].天津:天津科技大学,2017.
[29]Shukun Yu,Jie Mei,Bo Ahren.Basic toxicology and metabolism studies of 1,5-anhydro-D-fructoseusing bacteria,cultured mammalian cells,and rodents[J].Food and Chemical Toxicology,2004,42:1677-1686.
[30]Yao L,Yuan Y,Lin L,et al.Carboxymethylation of polysaccharide from Morchella angusticepes,Peck enhances its cholesterol-lowering activity in rats[J].Carbohydrate Polymers,2017,172:85.
[31]曾维才,石碧.天然产物抗氧化活性的常见评价方法[J].化工进展,2013,32(6):1205-1213.
[32]毕博,于荣利.尖顶羊肚菌多糖的超声波辅助提取工艺优化及其对肝损伤小鼠抗氧化活性的影响[J].食用菌学报,2016,23(3):53-56.
[33]Fanyun Meng,Bo Zhou,Rongshan Lin,et al.Extraction optimization and in vivo antioxidant activities of exopolysaccharideby Morchella esculenta SO-01.[J].Bioresource Technology,2010,101:4564-4569.
[34]冮洁,麦海美,解彬,等.羊肚菌菌丝体富硒条件优化及其硒多糖抗氧化活性研究[J].食品与发酵工业,2016,42(9):120-125.
[35]黄玲玲,苏彩霞,张宗申,等.硒、锌元素对羊肚菌多糖抗氧化性的影响[J].食品与发酵工业,2015,41(7):122-125.
[36]Gursoy N,Sari Kurkcu C,Cengi Z M,et al.Antioxidant activities,metal contents,total phenolics and flavonoids of seven Morchella species[J].Food&Chemical Toxicology An International Journal Published for the British Industrial Biological Research Association,2009,47(9):2381-2388.
[37]Fu L,Wang Y,Wang J,et al.Evaluation of the antioxidant activity of extracellular polysaccharides from Morchella esculenta[J].Food&Function,2013,4(6):871.
[38]马利,李霞,张松.尖顶羊肚菌胞外多糖提取物对皮肤成纤维细胞增殖和衰老的影响[J].菌物学报,2014,33(2):385-393.
[39]江洁.羊肚菌富锌菌丝体多糖抗小鼠衰老的研究[A].中国食品科学技术学会.中国食品科学技术学会第十一届年会论文摘要集[C].中国食品科学技术学会,2014:2.
[40]姚珩,朱慧,陈野,等.羊肚菌发酵豆渣生产多糖及其功能性的研究[J].食品研究与开发,2017,38(9):149-153.
[41]明建,曾凯芳,赵国华,等.羊肚菌水溶性多糖PMEP-1降血脂作用研究[J].食品科学,2009,30(17):285-288.
[42]李爽,袁菱,马双双,等.多糖的化学结构及活性研究进展[J].西北药学杂志,2017(6):818-820.
[43]李谣,陈金龙,王丽颖,等.羊肚菌多糖抑制人乳腺癌细胞MDA-MB-231增殖和诱导细胞凋亡研究[J].食品科学,2016,37(21):214-218.
[44]Hu M,Chen Y,Wang C,et al.Induction of apoptosis in Hep G2 cells by polysaccharide MEP-II from the fermentation broth of Morchella esculenta[J].Biotechnology Letters,2013,35(1):1-10.
[45]薛莉.羊肚菌胞外粗多糖对S_(180)肉瘤小鼠的抑制实验[J].山西中医学院学报,2014,15(2):27-29.
[46]陈彦,潘见,周丽伟,等.羊肚菌胞外多糖抗肿瘤作用的研究[J].食品科学,2008,29(9):553-556.
[47]Huang M,Zhang S,Zhang M,et al.Effects of polysaccharides from Morchella conica,on nitric oxide production in lipopolysaccharide-treated macrophages[J].Applied Microbiology&Biotechnology,2012,94(3):763.
[48]王嘉瑛.天然多糖对运动性疲劳的作用[J].当代体育科技,2016,6(33):12-13.
[49]段巍鹤,郭瑞,张起莹,等.羊肚菌活性成分应急性抗疲劳功能的研究[J].安徽农业科学,2015,43(8):1-3.
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