发酵果蔬汁的通便和减肥功能
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摘要
使用盐酸洛哌丁胺构建小鼠功能性便秘模型,使用高热量饲料构建大鼠营养性肥胖模型。实验动物均按体重随机分成5组:空白对照组、模型对照组和发酵果蔬汁低、中、高3个干预剂量组。3个发酵果蔬汁干预组每天分别灌胃2. 1、4. 2和8. 4 m L/kg发酵果蔬汁,空白对照组和模型对照组在相同时间内每天灌胃蒸馏水。通便功能评价实验检测小肠运动和排便,减肥功能评价实验检测体重和体脂。结果发现发酵果蔬汁组墨汁推进率、排首粒黑便时间和5 h排黑便粒数与模型对照组相比有显著改善;发酵果蔬汁组体重、睾丸及肾周脂肪重和脂/体比显著低于模型对照组。发酵果蔬汁具有一定的通便和减肥功能。
In order to evaluate the functions of fermented fruit and vegetable juices for defecation and weight loss,a functional constipation model of mice was established by loperamide hydrochloride,and a model of nutritional obesity was established by feeding rats high calorie feeds. Mice were randomly divided into five groups based on their weight as follows: the blank control group,the model control group,and three experimental groups. The blank and model control groups were treated with distilled water every day at the same time as the experimental groups were given2. 1 m L/kg,4. 2 m L/kg,and 8. 4 m L/kg fermented fruit and vegetable juices. The bowel movement and defecation were measured in laxative function evaluation experiments,and body weight and body fat were measured in weight loss function evaluation experiments. The results showed that the ink propulsion rate,time of producing the first black stool,and the dejection amounts within 5 h were significantly improved in experimental groups compared with the model control group. The body weight,the weight of testicles,perirenal fat,and the ratio of fat weight to body weight in experimental groups were significantly lower than that of the model centrol group. In conclusion,fermented fruit and vegetable juices played an important role in the laxative function and weight loss.
In order to evaluate the functions of fermented fruit and vegetable juices for defecation and weight loss,a functional constipation model of mice was established by loperamide hydrochloride,and a model of nutritional obesity was established by feeding rats high calorie feeds. Mice were randomly divided into five groups based on their weight as follows: the blank control group,the model control group,and three experimental groups. The blank and model control groups were treated with distilled water every day at the same time as the experimental groups were given2. 1 m L/kg,4. 2 m L/kg,and 8. 4 m L/kg fermented fruit and vegetable juices. The bowel movement and defecation were measured in laxative function evaluation experiments,and body weight and body fat were measured in weight loss function evaluation experiments. The results showed that the ink propulsion rate,time of producing the first black stool,and the dejection amounts within 5 h were significantly improved in experimental groups compared with the model control group. The body weight,the weight of testicles,perirenal fat,and the ratio of fat weight to body weight in experimental groups were significantly lower than that of the model centrol group. In conclusion,fermented fruit and vegetable juices played an important role in the laxative function and weight loss.
引文
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[14]苓朋春,张印红,李志玲,等.复合膳食纤维对便秘患者的通便功能改善作用[J].慢性病学杂志,2016,17(6):671-672.
[15]陈垚,孙川喻,吕志敏.某复合膳食纤维对小鼠通便功能的影响研究[J].预防医学论坛,2017,23(3):156;236-237.
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[17]商龙臣,李晶,李斌.膳食纤维饱腹感的研究进展[J].食品安全质量检测学报,2018,9(2):372-379.
[2]尹曼,王一侠,魏颖,等.复合果蔬乳酸菌发酵产物分析及功能性评价[J].食品工业,2016,37(11):215-219.
[3]白浩,文佳嘉,费爽雯,等.酵素的功能与综合应用研究进展[J].食品工业,2017,38(6):270-272.
[4]中华医学会消化病学分会胃肠动力学组.中国慢性便秘诊治指南(2013年,武汉)[J].中华消化杂志,2013,33(5):605-612.
[5] BASILISCO G,COLETTA M. Chronic constipation:a critical review[J]. Digestive and Liver Disease,2013,45(11):886-893.
[6] JOHANSON J F,KRALSTEIN J. Chronic constipation:a survey of the patient perspective[J]. Alimentary Pharmacology&Therapeutics,2007,25(5):599-608.
[7]董吉林,朱莹莹,李林,等.燕麦膳食纤维对食源性肥胖小鼠降脂减肥作用研究[J].中国粮油学报,2015,30(9):24-29.
[8]刘敬科,赵巍,刘莹莹,等.小米糠膳食纤维制备工艺及通便特性的研究[J].食品科技,2014,39(2):177-181.
[9]王娟,汪雨亭,杨公明.香蕉不溶性膳食纤维的理化特性与通便功能研究[J].食品工业科技,2017,38(2):337-341.
[10]程明明,黄苇.西番莲果皮中膳食纤维的降脂保肝及润肠通便功能[J].食品科学,2017,38(11):202-207.
[11]刘芳丽.膳食纤维减肥功效的机理探讨[J].食品研究与开发,2007,28(4):156-159.
[12]朱静,张智钰.膳食纤维的提取工艺及减肥作用研究进展[J].食品安全导刊,2016(30):136-138.
[13]王丽卫,孙健,赵兵,等.肉苁蓉膳食纤维润肠通便功能研究[J].食品安全质量检测学报,2016,7(9):3 740-3 744.
[14]苓朋春,张印红,李志玲,等.复合膳食纤维对便秘患者的通便功能改善作用[J].慢性病学杂志,2016,17(6):671-672.
[15]陈垚,孙川喻,吕志敏.某复合膳食纤维对小鼠通便功能的影响研究[J].预防医学论坛,2017,23(3):156;236-237.
[16]陈亚非,葛亚中,罗琦珊.复合膳食纤维通便作用的研究[J].现代食品科技,2005,21(2):43-46.
[17]商龙臣,李晶,李斌.膳食纤维饱腹感的研究进展[J].食品安全质量检测学报,2018,9(2):372-379.