不同强度有氧运动对代谢综合征患者心血管危险因子的干预效果分析
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摘要
目的:为了探究不同强度有氧运动对代谢综合征患者心血管危险因子的影响。方法:以26名中年女性代谢综合征患者为对象,进行实验研究。实验分为中等强度有氧运动组(n=9)、高强度有氧运动组(n=9)和对照组(n=8),为期12周,每周5次,在跑步机上进行慢跑+走的运动干预。采用心率储备(heart rate reserve:%HRR)设定运动强度。中等强度为40%~60%HRR,高强度为60%~80%HRR,采用Polar Heart Rate Analyzer(Polar Electro OY,Filand)对运动过程中的心率进行监控。结果:1)实验后,中等强度有氧运动组和高强度有氧运动组的体重、体脂率、腰围、收缩期血压、舒张期血压、总胆固醇、中性脂肪、LDL-c、空腹血糖等指标均显著降低,HDL-c显著升高。中等强度运动组与高强度运动组组间差异不显著。而对照组实验前后各项指标均无显著变化。2)中等强度有氧运动组和高强度有氧运动组的空腹胰岛素、胰岛素抵抗指数、肾素、血管紧张素Ⅱ、C-反应蛋白与实验前相比,均显著降低,对照组未发生显著变化。中等强度有氧运动组和高强度有氧运动组未发生显著性差异。结论:有氧运动对改善代谢综合征患者的心血管危险因子具有积极作用,中等强度有氧运动与高强度有氧运动效果不存在显著差异。由于高强度有氧运动容易引起身心疲劳,存在一定的运动风险,建议代谢综合征患者采用中等强度有氧运动进行练习。
The purpose is to investigate the effects of aerobic exercise intensity on cardiovascular risk factors in patients with metabolic syndrome. The subjects were middle-aged women with metabolic syndrome. The subjects were randomly divided into three groups: moderate-intensity group(n = 9,40% ~ 60% HRR),high-intensity group(n = 9,40% ~ 60%HRR),and control group(n = 8). The groups were invited to participate in an exercise program consisting of a treadmill running or walking for 12 weeks with frequency of 5 times per week. The following results were found: firstly,the weight,percent body fat,waist circumstance,systolic blood pressure,diastolic blood pressure,fasting glucose,Tc,Tg and LDL-c were significantly decreased in both moderate and high-intensity exercise groups after treatment,but the HDL-c levels were significantly increased. There were no differences between moderate-intensity exercise group and high-intensity exercise group. There were no significant changes in the indexes of control group before and after the experiment. Secondly,The insulin,insulin resistance,renin-angiotensinⅡlevels,C-reactive protein were significantly decreased than those after treatment in both moderate and high-intensity aerobic exercise and those of the control group had no changes. There were no obvious differences between moderate-intensity exercise group and high-intensity exercise group. Conclusions: Aerobic exercise has a positive effect on cardiovascular risk factors in patients with metabolic syndrome,and moderate and high-intensity aerobic exercises have no remarkable differences. Because the high-intensity aerobic exercise can easily lead to physical and mental fatigue,which has a certain risk of exercise,it is suggested that patients with metabolic syndrome should be treated with moderate intensity aerobic exercise.
The purpose is to investigate the effects of aerobic exercise intensity on cardiovascular risk factors in patients with metabolic syndrome. The subjects were middle-aged women with metabolic syndrome. The subjects were randomly divided into three groups: moderate-intensity group(n = 9,40% ~ 60% HRR),high-intensity group(n = 9,40% ~ 60%HRR),and control group(n = 8). The groups were invited to participate in an exercise program consisting of a treadmill running or walking for 12 weeks with frequency of 5 times per week. The following results were found: firstly,the weight,percent body fat,waist circumstance,systolic blood pressure,diastolic blood pressure,fasting glucose,Tc,Tg and LDL-c were significantly decreased in both moderate and high-intensity exercise groups after treatment,but the HDL-c levels were significantly increased. There were no differences between moderate-intensity exercise group and high-intensity exercise group. There were no significant changes in the indexes of control group before and after the experiment. Secondly,The insulin,insulin resistance,renin-angiotensinⅡlevels,C-reactive protein were significantly decreased than those after treatment in both moderate and high-intensity aerobic exercise and those of the control group had no changes. There were no obvious differences between moderate-intensity exercise group and high-intensity exercise group. Conclusions: Aerobic exercise has a positive effect on cardiovascular risk factors in patients with metabolic syndrome,and moderate and high-intensity aerobic exercises have no remarkable differences. Because the high-intensity aerobic exercise can easily lead to physical and mental fatigue,which has a certain risk of exercise,it is suggested that patients with metabolic syndrome should be treated with moderate intensity aerobic exercise.
引文
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[13]王国祥,李长宏.内脏脂肪型肥胖症与运动疗法[J].中国临床康复,2004,8(33):7524-7525.
[14]Kamejiro,Yamashita.Prescription of physical exercise for diabetes[J].Diabetes,1998,41:229-238.
[15]Houmard,J.A.,Tanner,C.J.,Slentz,C.A.,et al.Effects of the volume and intensity of exercise training on insulin sensitivity[J].Journal of Applied Physiology,2003,96:101-103.
[16]金妍洙.运动与营养教育对胰岛素抵抗性代谢综合征患者的心肺机能与身体构成的影响[J].韩国体育科学,2005,16(2):54-63.
[17]郑日浩.12周走步运动对2型糖尿病患者的身体组成及代谢综合征指标的影响[J].韩国运动研究,2007,18:697-708.
[18]何万东,李晋坤.1年自发性运动参与对中年男性2型糖尿病患者的血脂成分的影响[J].韩国发育发达学会志,2006,14(3):113-121.
[19]允美术.有氧运动对高血压患者的血压调节激素和心脏机能与最大摄氧量的影响[J].韩国体育学会志,2003,12(2):197-222.
[2]Osei,K.Insulin resistance and systemic hypertension[J].American Journal of Cardiology,1999,84:33-36.
[3]Richey,J.M.,Moore,D.,Bergman,R.N.AngiotensionⅡinduces insulin resistance independent of changes in interstitial insulin[J].American Journal of Physiology,1999,277:920-926.
[4]Abussa,H.,Jones,P.G.,Marso,S.P.,et al.Angiotensin-converting enzyme inhibitor or angiotensin receptor blocker for prevention of type 2 diabetes:a meta-analysis of randomized clinical trials[J].Journal of American Cardiology,2005,46(5):821-826.
[5]Rader,D.Inflammatory markers of coronary risk[J].NewEngland Journal of Medicine,2000,343:1179-1182.
[6]Swain,D.P.,Franklin,B.A.Comparison of cardiovascular benefits of aerobic exercise[J].American Journal of Cardiology,2006,97:141-147.
[7]徐国琴,林文弢.运动对2型糖尿病的影响[J].广州体育学院学报,2002,22(1):53-56.
[8](韩国)朴洙宪,韩泰京,李申浩,姜宪植.12周走步运动强度对肥胖女性身体组成腹部脂肪,心肺体力的影响[J].运动科学,2007,16(1):1-10.
[9]Janssen,I.,Hudson,R.,Fortier,A.,et al.Effects of an energy-restrictive diet with or without exercise on abdominal fat,intermuscular fat,and metabolic risk factors in obese women[J].Diabetes Care,2002,25(3):431-438.
[10]Landsberg,L.Insulin-mediated sympathetic stimulation:role in the pathogenesis of obesity-related hypertension(or howinsulin affects blood pressure,and why)[J].Journal of Hypertension,2001,19:523-528.
[11]Arakaward,K.Antihypertensive mechanism of exercise[J].Journal of Hypertension,1993,11:223-239.
[12]Dengel,d.r.,Hagberg,J.M.,Prately,R.E.,et al.Improvements in blood pressure,glucose metabolism,and lipids after exercise plus weight loss in obese,hypertensive middle-aged men[J].Metabolism,1998,47(9):1075-1082.
[13]王国祥,李长宏.内脏脂肪型肥胖症与运动疗法[J].中国临床康复,2004,8(33):7524-7525.
[14]Kamejiro,Yamashita.Prescription of physical exercise for diabetes[J].Diabetes,1998,41:229-238.
[15]Houmard,J.A.,Tanner,C.J.,Slentz,C.A.,et al.Effects of the volume and intensity of exercise training on insulin sensitivity[J].Journal of Applied Physiology,2003,96:101-103.
[16]金妍洙.运动与营养教育对胰岛素抵抗性代谢综合征患者的心肺机能与身体构成的影响[J].韩国体育科学,2005,16(2):54-63.
[17]郑日浩.12周走步运动对2型糖尿病患者的身体组成及代谢综合征指标的影响[J].韩国运动研究,2007,18:697-708.
[18]何万东,李晋坤.1年自发性运动参与对中年男性2型糖尿病患者的血脂成分的影响[J].韩国发育发达学会志,2006,14(3):113-121.
[19]允美术.有氧运动对高血压患者的血压调节激素和心脏机能与最大摄氧量的影响[J].韩国体育学会志,2003,12(2):197-222.