鱼油的提取、富集与应用研究进展
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摘要
鱼油中富含Omega-3不饱和脂肪酸,尤其是特征性脂肪酸二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)。鱼油具有预防心血管疾病,降低胆固醇,促进血液循环,防止心脑血管疾病,抑制过敏反应,减少动脉硬化,降脂降压,消除疲劳,缓和痛风及风湿性关节炎,促进婴儿视网膜发育等功效。由于鱼油独特的功能特性,鱼油的应用十分广泛。近年来,随着人们对鱼油的营养及保健功能的认可,鱼油的提取、富集及应用也成为研究的热点。对鱼油的提取、富集方法及在食品、饲料和疾病防治中的应用进行了总结、分析和探讨,为鱼油的加工与应用提供参考。
Omega-3 unsaturated fatty acids are rich in fish oil,especially the characteristic fatty acids EPA and DHA.Fish oil has the function of preventing cardiovascular disease,lowering cholesterol levels,promoting blood circulation,preventing disease of heart head blood-vessel,inhibiting allergic reactions,reducing hardening of the arteries,lipid-lowering buck,eliminating fatigue,moderating gout and rheumatoid arthritis,promoting baby retinal development and so on.Because of the unique features of fish oil,the application of fish oil is very extensive.In recent years,as people's recognition to the nutrition and healthcare function of fish oil,the extraction,refining and application of fish oil have become a research hotspot.The extraction method,enrichment method and application in food,feed and disease prevention and control of fish oil were summarized,analyzed and discussed,to provide reference for the processing and application of fish oil.
Omega-3 unsaturated fatty acids are rich in fish oil,especially the characteristic fatty acids EPA and DHA.Fish oil has the function of preventing cardiovascular disease,lowering cholesterol levels,promoting blood circulation,preventing disease of heart head blood-vessel,inhibiting allergic reactions,reducing hardening of the arteries,lipid-lowering buck,eliminating fatigue,moderating gout and rheumatoid arthritis,promoting baby retinal development and so on.Because of the unique features of fish oil,the application of fish oil is very extensive.In recent years,as people's recognition to the nutrition and healthcare function of fish oil,the extraction,refining and application of fish oil have become a research hotspot.The extraction method,enrichment method and application in food,feed and disease prevention and control of fish oil were summarized,analyzed and discussed,to provide reference for the processing and application of fish oil.
引文
[1]黄明发,吴桂苹,焦必宁.二十碳五烯酸和二十二碳六烯酸的生理功能[J].食品与药品,2007,9(2):69-71.
[2]王萍,张银波,江木兰.多不饱和脂肪酸的研究进展[J].中国油脂,2008,33(12):42-46.
[3]曹万新,孟橘,田玉霞.DHA的生理功能及应用研究进展[J].中国油脂,2011,36(3):1-4.
[4]周远扬,雷百战,潘艺.鱼油EPA与DHA提取方法研究进展[J].广东农业科学,2009(12):153-155.
[5]陶宁萍,鲍丹.鱼油的营养和药用价值及其提取工艺的研究进展[J].上海水产大学学报,2005,14(2):197-201.
[6]王海磊,罗庆华,黄美娥.鱼油的提取方法及精制工艺探讨[J].湖南农业科学,2012(9):99-102.
[7]Liu Qiyuan.Dietary fish oil and vitamin E enhance doxorubicin effects in P388 tumor-bearing mice[J].Lipids,2002,37(6):549-556.
[8]朱明.食品工业分离技术[M].北京:化学工业出版社,2005.
[9]曹明霞,徐溢,赵天明,等.超临界萃取在天然植物成分提取中的应用进展[J].广州化工,2010,38(8):23-25.
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[11]陶海荣,李和.从鱼油中分离高纯度的EPA和DHA[J].中国海洋药物,2000,19(5):24-26.
[12]王学彤,张书圣,白吉洪,等.高效液相色谱法分离制备鱼油中的EPA和DHA[J].分析试验室,1999,18(1):42-45.
[13]杨博,杨继国,吕杨效,等.脂肪酶催化鱼油醇解富集EPA和DHA的研究[J].中国油脂,2005,30(8):64-67.
[14]翁新楚,董新伟,任国谱.脲包法在脂类分离技术中的应用[J].中国油脂,1994,19(6):40-43.
[15]朱世云,包宗宏,云志,等.尿素包合法富集鱼油中的EPA和DHA的研究[J].中国油脂,1997,22(5):54-56.
[16]王娟娟,黄宏南,许晨,等.脲包法富集鱼油中的EPA和DHA的研究[J].海峡预防医学杂志,2012,18(1):61-62.
[17]张相年,刘演波,赵树进,等.从深海鱼油中制备提纯二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)乙酯的研究[J].广州药学院学报,1999,15(3):171-173.
[18]郑美瑜,程绍南,邢建荣,等.超临界CO2连续式萃取鱼油中EPA和DHA的优化试验[J].粮油加工与食品机械,2004(8):37-38.
[19]Wojciech K,Franciszek S,Stanislaw B.Possibilities of fish oil application for food products enrichment withω-3 PUFA[J].International Journal of Food Science and Nutrition,1999,50(1):39-49.
[20]Deirdre N E,David O B.Oxidative stability and acceptability of camelina oil blended with selected fish oils[J].European Journal of Lipid Science and Technology,2010,112(8):878-886.
[21]Let M B,Jacobsen C,Meyer A S.Lipid oxidation in milk,yoghurt,and salad dressing enriched with neat fish oil or pre-emulsified fish oil[J].Journal of Agricultural and Food Chem,2007,55(19):7802-7809.
[22]Farvin S K H,Baron C P,Nielsen N S.Antioxidant activity of yoghurt peptides:part 1-in vitro assays and evaluation inω-3 enriched milk[J].Food Chemistry,2010,123(4):1081-1089.
[23]Barrow C J,Nolan C,Holub J.Bioequivalence of encapsulated and microencapsulated fish-oil supplementation[J].Journal of Functional Foods,2009,1(1):38-43.
[24]高淳仁,雷霁霖.饲料中氧化鱼油对真鲷幼鱼生长、存活及脂肪酸组成的影响[J].上海水产大学学报,1999,8(2):124-130.
[25]肖成林,田春庄,黄若飞,等.母猪日粮中的鱼油对乳中脂肪酸和仔猪生长性能的影响[J].动物营养学报,2008,20(1):8-15.
[26]卓勇,吴德,方正锋,等.日粮添加鱼油对母猪繁殖性能的影响[J].动物营养学报,2010,22(2):251-258.
[27]张丽英,王宝维,单虎,等.含红花籽油日粮中添加不同比例鱼油对蛋黄中多聚不饱和脂肪酸及胆固醇含量的影响[J].中国畜牧杂志,1997,33(6):35-37.
[28]倪根珊.药物临床应用撷萃[M].北京:八一出版社,1994.
[2]王萍,张银波,江木兰.多不饱和脂肪酸的研究进展[J].中国油脂,2008,33(12):42-46.
[3]曹万新,孟橘,田玉霞.DHA的生理功能及应用研究进展[J].中国油脂,2011,36(3):1-4.
[4]周远扬,雷百战,潘艺.鱼油EPA与DHA提取方法研究进展[J].广东农业科学,2009(12):153-155.
[5]陶宁萍,鲍丹.鱼油的营养和药用价值及其提取工艺的研究进展[J].上海水产大学学报,2005,14(2):197-201.
[6]王海磊,罗庆华,黄美娥.鱼油的提取方法及精制工艺探讨[J].湖南农业科学,2012(9):99-102.
[7]Liu Qiyuan.Dietary fish oil and vitamin E enhance doxorubicin effects in P388 tumor-bearing mice[J].Lipids,2002,37(6):549-556.
[8]朱明.食品工业分离技术[M].北京:化学工业出版社,2005.
[9]曹明霞,徐溢,赵天明,等.超临界萃取在天然植物成分提取中的应用进展[J].广州化工,2010,38(8):23-25.
[10]Rodriguez N R,Diego S M,Beltran S,et al.Supercritical fluid extraction of fish oil from fish by-products:A comparison with other methods[J].Food Engineering,2012,109:238-248.
[11]陶海荣,李和.从鱼油中分离高纯度的EPA和DHA[J].中国海洋药物,2000,19(5):24-26.
[12]王学彤,张书圣,白吉洪,等.高效液相色谱法分离制备鱼油中的EPA和DHA[J].分析试验室,1999,18(1):42-45.
[13]杨博,杨继国,吕杨效,等.脂肪酶催化鱼油醇解富集EPA和DHA的研究[J].中国油脂,2005,30(8):64-67.
[14]翁新楚,董新伟,任国谱.脲包法在脂类分离技术中的应用[J].中国油脂,1994,19(6):40-43.
[15]朱世云,包宗宏,云志,等.尿素包合法富集鱼油中的EPA和DHA的研究[J].中国油脂,1997,22(5):54-56.
[16]王娟娟,黄宏南,许晨,等.脲包法富集鱼油中的EPA和DHA的研究[J].海峡预防医学杂志,2012,18(1):61-62.
[17]张相年,刘演波,赵树进,等.从深海鱼油中制备提纯二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)乙酯的研究[J].广州药学院学报,1999,15(3):171-173.
[18]郑美瑜,程绍南,邢建荣,等.超临界CO2连续式萃取鱼油中EPA和DHA的优化试验[J].粮油加工与食品机械,2004(8):37-38.
[19]Wojciech K,Franciszek S,Stanislaw B.Possibilities of fish oil application for food products enrichment withω-3 PUFA[J].International Journal of Food Science and Nutrition,1999,50(1):39-49.
[20]Deirdre N E,David O B.Oxidative stability and acceptability of camelina oil blended with selected fish oils[J].European Journal of Lipid Science and Technology,2010,112(8):878-886.
[21]Let M B,Jacobsen C,Meyer A S.Lipid oxidation in milk,yoghurt,and salad dressing enriched with neat fish oil or pre-emulsified fish oil[J].Journal of Agricultural and Food Chem,2007,55(19):7802-7809.
[22]Farvin S K H,Baron C P,Nielsen N S.Antioxidant activity of yoghurt peptides:part 1-in vitro assays and evaluation inω-3 enriched milk[J].Food Chemistry,2010,123(4):1081-1089.
[23]Barrow C J,Nolan C,Holub J.Bioequivalence of encapsulated and microencapsulated fish-oil supplementation[J].Journal of Functional Foods,2009,1(1):38-43.
[24]高淳仁,雷霁霖.饲料中氧化鱼油对真鲷幼鱼生长、存活及脂肪酸组成的影响[J].上海水产大学学报,1999,8(2):124-130.
[25]肖成林,田春庄,黄若飞,等.母猪日粮中的鱼油对乳中脂肪酸和仔猪生长性能的影响[J].动物营养学报,2008,20(1):8-15.
[26]卓勇,吴德,方正锋,等.日粮添加鱼油对母猪繁殖性能的影响[J].动物营养学报,2010,22(2):251-258.
[27]张丽英,王宝维,单虎,等.含红花籽油日粮中添加不同比例鱼油对蛋黄中多聚不饱和脂肪酸及胆固醇含量的影响[J].中国畜牧杂志,1997,33(6):35-37.
[28]倪根珊.药物临床应用撷萃[M].北京:八一出版社,1994.