2,2-二氟-1,3-丙二醇的制备方法及其在药物合成中的应用
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摘要
本文对2,2-二氟-1,3-丙二醇的制备方法及其在药物合成中的应用进行了较为详细的介绍。
The preparation methods of 2,2-difluoropropane-1,3-diol and its applications in drug synthesis were summarized.
The preparation methods of 2,2-difluoropropane-1,3-diol and its applications in drug synthesis were summarized.
引文
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[2]党丽,倪绍飞.一种化合物及其应用:CN,107383107[P].2017-11-24.
[3]夏行.一种耐候聚酯粉末涂料及其制备方法:CN,105400254[P].2016-03-16.
[4]Fujii Yusuke,Kyoda Hirokazu.Ink compositions with good flexibility and curability under high-humidity environment,ink-jet printing method using them,and their printed articles:JP,2011190362[P].2011-09-29.
[5]Groenendaal B,Reynolds J R,Gaupp C L,et al.3,4-alkylenedioxythiophene compounds and polymers thereof:US,2004072987[P].2004-04-15.
[6]Funaki Atsushi,Kato Kazuo,Takakura Teruo.Nonpolluting manufacture of fluorine-containing polymers:JPH,06157610[P].1994-06-07.
[7]Fear E J P,Thrower J.Organic fluorine compounds IV.Some reactions of difluoromalonyl chloride,and the action of iodine on di-silver difluoromalonate[J].Journal of the Chemical Society,1956:3199-3204.
[8]Hillebrand S,Mattes A,Sudau A,et al.Preparation of heterocyclylpyri(mi)dinylpyrazoles as agricultural fungicides:WO,2013050437[P].2013-04-11.
[9]Boguslavskaya L S,Etlis V S,Yarovykh K V,et al.Coupled halogenation of unsaturated compounds IV:Chlorofluorination of 2-haloallyl alcohols and some reactions of fluorochloropropanols[J].Zhurnal Organicheskoi Khimii,1971,7(7):1338-1343.
[10]魏坤,肖玉岭.一种2,2-二氟-1,3-丙二醇的制备方法:CN,107400040[P].2017-11-28.
[11]Catalano J G,Dickson H D,Kazmierski W M,et al.Dihydroquinolizinones as antivirals:WO,2018154466[P].2018-08-30.
[12]Anderson D,Volkmann R,Menniti F,et al.NMDA receptor modulators and uses thereof:WO,2018119374[P].2018-06-28.
[13]Barlaam B C,O'Donovan D H,Hughes S J,et al.NMDAreceptor modulators and uses thereof:US,2018111931[P].2018-04-26.
[14]Uesugi M,Kincaid J,Huff J.Disubstituted pyrazoles compounds for the treatment of diseases:WO,2018049080[P].2018-03-15.
[15]Scott J S,Moss T A,O'Donovan D H,et al.Chemical compounds:US,2018021316[P].2018-01-25.
[16]Campbell J E,Duncan K W,Foley M A,et al.Aminesubstituted aryl or heteroaryl compounds as EHMT1 and EHMT2 inhibitors:WO,2017181177[P].2017-10-19.
[17]Chessari G,Howard S,Buck I M,et al.Isoindolinones inhibitors of the MDM2-P53 interaction having anticancer activity:WO,2017055860[P].2017-04-06.
[18]Luecking U,Cleve A,Haendler B,et al.Substituted(heteroarylmethyl)thiohydantoins:US,2012251551[P].2012-10-04.
[19]Goodacre S C,Labadie S,Liang J,et al.Tetrahydro-pyrido[3,4-b]indole estrogen receptor modulators and uses thereof:WO,2016097072[P].2016-06-23.
[20]Bartels B,Cueni P,Dolente C,et al.BACE1 inhibitors:WO,2016055496[P].2016-04-14.
[21]Lewis R T,Choquette D,Epstein O,et al.Aminodihydrothiazine and aminodioxidodihydrothiazine compounds as beta-secretase antagonists and methods of use:WO,2014059185[P].2014-04-17.
[22]Brubaker J,Close J,Siu T,et al.Pyrazolecarboxamides as janus kinase inhibitors:WO,2013041042[P].2013-03-28.
[23]Matsunaga N,Igawa H,Suzuki H,et al.Heterocyclic compound and application thereof:WO,2012011592[P].2012-01-26.
[24]Crew A P,Dong H Q,Ferraro C,et al.Isoindolinones inhibitors of the MDM2-P53 interaction having anticancer activity:WO,2012074951[P].2012-06-07.
[25]Boyer St J,Gao D h A,Guo X,et al.Heterocyclic compounds containing an indole core:WO,2011071716[P].2011-06-16.
[26]Gai Y H,Or Y S,Wang G Q.Bismacrocyclic compounds as hepatitis C virus inhibitors:WO,2011049908[P].2011-04-28.