消溃愈疡汤联合艾迪莎治疗溃疡性结肠炎50例
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摘要
目的:观察消溃愈疡汤内服、灌肠联合艾迪莎内服治疗溃疡性结肠炎的临床疗效。方法:将符合病例入选标准的100例溃疡性结肠炎患者按就诊的先后顺序随机分为观察组、对照组各50例。2组患者入院后即嘱饮食以柔软、易消化、富含营养、富含维生素为主,对于有贫血、脱水症状者给予输血、输液等对症治疗,同时予艾迪莎,1.0 g/次,4次/d。观察组在此基础上予自拟消溃愈疡汤灌肠,1剂/d,早、晚各1次。2组均以1周为1个疗程,治疗2个疗程后观察疗效。结果:观察组治愈率为76.00%,总有效率为96.00%。对照组治愈率为60.00%,总有效率为82.00%。2组治愈率、总有效率相比,差异有统计学意义(P<0.05)。2组治疗后腹痛、腹泻、脓血便等症状积分较治疗前均明显降低(P<0.05),且治疗组降低较对照组更明显(P<0.05)。2组不良反应发生率相比,差异有统计学意义(P<0.05)。结论:消溃愈疡汤内服、灌肠联合艾迪莎内服治疗溃疡性结肠炎疗效显著,可迅速改善症状、体征,且不良反应低。
Objective:To verify clinical effects of XiaoKui YuYangTang for enema and oral etiasa in treating ulcerative colitis.Method: One hundred patients were randomized into the observation group and the control group according to the sequences of visit,50 cases each group.Both groups were put on soft,digestible and nutritive diet enriched of vitamin and given with corresponding treatment for anemia and dehydration.The observation group received XiaoKui YuYangTang for enema,one dose each day and twice per day.One course of treatment was one week,clinical effects were observed after two courses of treatment.Result: Cure rate and total effective rate of the observation group were 76.00% and 96.00%,higher than 60.00% and 82.00% of the control group with the difference,which demonstrated statistical meaning(P<0.05).Symptom scores of both groups were lowered after treating than before treating in abdominal pain,diarrhea,bloody purulent stool and others(P<0.05),and the observation group decreased greater than the control group(P<0.05).Comparison between both groups in incidences of adverse reaction showed the difference and it had statistical meaning(P<0.05).Conclusion: XiaoKui YuYangTang for enema and oral etiasa show notable effects in treating ulcerative colitis,which could improve symptoms and body signs with fewer adverse reactions.
Objective:To verify clinical effects of XiaoKui YuYangTang for enema and oral etiasa in treating ulcerative colitis.Method: One hundred patients were randomized into the observation group and the control group according to the sequences of visit,50 cases each group.Both groups were put on soft,digestible and nutritive diet enriched of vitamin and given with corresponding treatment for anemia and dehydration.The observation group received XiaoKui YuYangTang for enema,one dose each day and twice per day.One course of treatment was one week,clinical effects were observed after two courses of treatment.Result: Cure rate and total effective rate of the observation group were 76.00% and 96.00%,higher than 60.00% and 82.00% of the control group with the difference,which demonstrated statistical meaning(P<0.05).Symptom scores of both groups were lowered after treating than before treating in abdominal pain,diarrhea,bloody purulent stool and others(P<0.05),and the observation group decreased greater than the control group(P<0.05).Comparison between both groups in incidences of adverse reaction showed the difference and it had statistical meaning(P<0.05).Conclusion: XiaoKui YuYangTang for enema and oral etiasa show notable effects in treating ulcerative colitis,which could improve symptoms and body signs with fewer adverse reactions.
引文
[1]陈灏珠.实用内科学[M].12版.北京:人民卫生出版社,2006:1914-1916.
[2]全国慢性非感染性肠道疾病学术研讨会.溃疡性结肠炎的诊断及疗效标准[M].中华消化杂志,1993,13(6):354.
[3]张德正.溃疡性结肠炎的临床治疗与分析[J].中国现代医生,2007,45(8):37,89.
[4]王晓,刘凡.艾迪莎与柳氮磺胺吡啶治疗溃疡性结肠炎的近期疗效比较[J].中外医疗,2008,27(18):115-116.
[5]吴新宇,姜爱芳.艾迪莎治疗溃疡性结肠炎126例临床疗效观察[J].中国实用医药,2009,4(5):160.
[6]刘允.艾迪莎灌肠治疗溃疡性结肠炎40例疗效观察[J].中国误诊学杂志,2006,6(9):1710-1711.
[7]赵永玲.艾迪莎加药物灌肠联合治疗溃疡性结肠炎20例临床观察[J].中国医药指南,2008,6(15):110-111.
[8]王翼洲,刘应东.热瘀散治疗轻中度溃疡性结肠炎84例[J].西部中医药,2012,25(4):66-68.
[2]全国慢性非感染性肠道疾病学术研讨会.溃疡性结肠炎的诊断及疗效标准[M].中华消化杂志,1993,13(6):354.
[3]张德正.溃疡性结肠炎的临床治疗与分析[J].中国现代医生,2007,45(8):37,89.
[4]王晓,刘凡.艾迪莎与柳氮磺胺吡啶治疗溃疡性结肠炎的近期疗效比较[J].中外医疗,2008,27(18):115-116.
[5]吴新宇,姜爱芳.艾迪莎治疗溃疡性结肠炎126例临床疗效观察[J].中国实用医药,2009,4(5):160.
[6]刘允.艾迪莎灌肠治疗溃疡性结肠炎40例疗效观察[J].中国误诊学杂志,2006,6(9):1710-1711.
[7]赵永玲.艾迪莎加药物灌肠联合治疗溃疡性结肠炎20例临床观察[J].中国医药指南,2008,6(15):110-111.
[8]王翼洲,刘应东.热瘀散治疗轻中度溃疡性结肠炎84例[J].西部中医药,2012,25(4):66-68.