中药对宫颈癌放疗后并发症预防与治疗的研究进展
|
摘要
放射治疗是宫颈癌的主要治疗方式之一。由于在放疗过程中部分宫旁组织及器官对放射线的耐受力较差,导致放疗后出现大量不良反应和并发症,使得患者生活质量受到明显影响。中医疗法在恶性肿瘤放化疗过程中具有显著的增敏、减毒作用,并能对一些放疗中产生的并发症起到预防和治疗效果。随着人们对放疗并发症的关注,很多研究发现,中药制剂对宫颈癌放疗所引起的放射性直肠炎、膀胱炎及精神心理方面不良反应具有显著疗效。
Radiotherapy is one of the main treatment methods for cervical cancer. However, due to the poor tolerance of some paruterine tissues and organs to radiation during the course of radiotherapy, there are a lot of adverse reactions and complications after radiotherapy. The quality of life of the patients was significantly af fected.As an auxiliary treatment, traditional Chinese medicine(TCM) can significantly increase the sensitivity and reduce the toxicity of malignant tumor in the course of radiotherapy and chemotherapy, and can prevent and treat some complications caused by radiotherapy. In recent years, with the attention of people on the complications of radiotherapy, many studies have found that the preparation of Chinese materia medica have significant effects on radiation proctitis, cystitis and psychosocial adverse reactions caused by cervical cancer radiotherapy.
Radiotherapy is one of the main treatment methods for cervical cancer. However, due to the poor tolerance of some paruterine tissues and organs to radiation during the course of radiotherapy, there are a lot of adverse reactions and complications after radiotherapy. The quality of life of the patients was significantly af fected.As an auxiliary treatment, traditional Chinese medicine(TCM) can significantly increase the sensitivity and reduce the toxicity of malignant tumor in the course of radiotherapy and chemotherapy, and can prevent and treat some complications caused by radiotherapy. In recent years, with the attention of people on the complications of radiotherapy, many studies have found that the preparation of Chinese materia medica have significant effects on radiation proctitis, cystitis and psychosocial adverse reactions caused by cervical cancer radiotherapy.
引文
[1]WEN H W,LIU T Y,FENG Z T,et al.Treatment results of adjuvant chemotherapy after radical hysterectomy for intermediate-risk stage IB-IIB cervical cancer[J].Journal of Cancer Therapy,2015,6(12).
[2]PETERSEN S,PETERSEN C.Radiation-induced sequelae affecting the continenc organ:Incidence,pathogenesis,and treat-ment[J].Diseases of the Colon&Rectum,2007,50(9):1466-1474.
[3]沈红梅,李文辉,黄杰,等.中药保留灌肠预防及治疗放射性直肠炎的现状[J].北京中医药,2009,28(7):559-561.
[4]李霞林.加味槐花散联合亮菌混合液保留灌肠治疗放射性肠炎的临床观察[D].合肥:安徽中医药大学,2016.
[5]孟晔,刘珂.康复新液口服结合中药口服灌肠治疗宫颈癌放疗后急性放射性直肠炎临床观察[J].中国中医急症,2015,24(12):2213-2215.
[6]毛玉荣,浦红,张振宇,等.医用三氧联合中药保留灌肠治疗宫颈癌放射性直肠炎的疗效分析[J].肿瘤药学,2016,6(6):433-436.
[7]刘雪梅.临床常用药物保留灌肠治疗放射性直肠炎疗效的回顾性研究[D].泸州:西南医科大学,2016.
[8]张东峰,赵学红,张艳明.中西医结合治疗宫颈癌放疗后膀胱炎和直肠炎临床观察[J].光明中医,2019,34(3):456-458.
[9]南新记.参七二甲汤治疗宫颈癌放疗后放射性膀胱炎64例[J].国医论坛,2012,27(3):30.
[10]王海媚,刘寨东.恶性肿瘤并发出血的中医辨证施治[J].中国中医急症,2017,26(6):987-989.
[11]程明珠.内服中药汤剂联合护理干预在宫颈癌腔内放疗后出血患者中的效果分析[J].实用妇科内分泌杂志(电子版),2017,4(20):107-108.
[12]董秀芳.爱宝疗配合中药内服治疗宫颈癌腔内放疗后出血疗效观察[J].新中医,2015,47(8):198-199.
[13]徐达稳,夏建华,朱海文,等.八珍汤加味预防宫颈癌放疗血液学毒副反应临床观察[J].中国肿瘤临床与康复,2011,18(6):546-548.
[14]曹红春.加味六味地黄汤治疗肿瘤化疗所致的血小板减少症的临床疗效观察[D].成都:成都中医药大学,2016.
[15]李松.裴氏升血颗粒对中晚期宫颈癌放疗疗效及生存质量的临床观察[D].兰州:甘肃中医药大学,2015.
[16]邰云燕.复方斑蝥胶囊联合放疗治疗宫颈癌的临床观察[D].武汉:湖北中医药大学,2015.
[17]张莹莹,靳莉莉,崔婷.六君子汤对宫颈癌辅助放化疗患者免疫功能、癌因性疲乏与生活质量的影响[J].中华中医药学刊,2018,36(7):1721-1723.
[18]邓守恒,段霞,陈萍.鸦胆子油乳在宫颈癌放疗中的作用观察[J].时珍国医国药,2015,26(8):1940-1942.
[2]PETERSEN S,PETERSEN C.Radiation-induced sequelae affecting the continenc organ:Incidence,pathogenesis,and treat-ment[J].Diseases of the Colon&Rectum,2007,50(9):1466-1474.
[3]沈红梅,李文辉,黄杰,等.中药保留灌肠预防及治疗放射性直肠炎的现状[J].北京中医药,2009,28(7):559-561.
[4]李霞林.加味槐花散联合亮菌混合液保留灌肠治疗放射性肠炎的临床观察[D].合肥:安徽中医药大学,2016.
[5]孟晔,刘珂.康复新液口服结合中药口服灌肠治疗宫颈癌放疗后急性放射性直肠炎临床观察[J].中国中医急症,2015,24(12):2213-2215.
[6]毛玉荣,浦红,张振宇,等.医用三氧联合中药保留灌肠治疗宫颈癌放射性直肠炎的疗效分析[J].肿瘤药学,2016,6(6):433-436.
[7]刘雪梅.临床常用药物保留灌肠治疗放射性直肠炎疗效的回顾性研究[D].泸州:西南医科大学,2016.
[8]张东峰,赵学红,张艳明.中西医结合治疗宫颈癌放疗后膀胱炎和直肠炎临床观察[J].光明中医,2019,34(3):456-458.
[9]南新记.参七二甲汤治疗宫颈癌放疗后放射性膀胱炎64例[J].国医论坛,2012,27(3):30.
[10]王海媚,刘寨东.恶性肿瘤并发出血的中医辨证施治[J].中国中医急症,2017,26(6):987-989.
[11]程明珠.内服中药汤剂联合护理干预在宫颈癌腔内放疗后出血患者中的效果分析[J].实用妇科内分泌杂志(电子版),2017,4(20):107-108.
[12]董秀芳.爱宝疗配合中药内服治疗宫颈癌腔内放疗后出血疗效观察[J].新中医,2015,47(8):198-199.
[13]徐达稳,夏建华,朱海文,等.八珍汤加味预防宫颈癌放疗血液学毒副反应临床观察[J].中国肿瘤临床与康复,2011,18(6):546-548.
[14]曹红春.加味六味地黄汤治疗肿瘤化疗所致的血小板减少症的临床疗效观察[D].成都:成都中医药大学,2016.
[15]李松.裴氏升血颗粒对中晚期宫颈癌放疗疗效及生存质量的临床观察[D].兰州:甘肃中医药大学,2015.
[16]邰云燕.复方斑蝥胶囊联合放疗治疗宫颈癌的临床观察[D].武汉:湖北中医药大学,2015.
[17]张莹莹,靳莉莉,崔婷.六君子汤对宫颈癌辅助放化疗患者免疫功能、癌因性疲乏与生活质量的影响[J].中华中医药学刊,2018,36(7):1721-1723.
[18]邓守恒,段霞,陈萍.鸦胆子油乳在宫颈癌放疗中的作用观察[J].时珍国医国药,2015,26(8):1940-1942.