当归芍药散治疗慢性肾小球肾炎湿瘀互结证临床观察
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摘要
目的了解中医辨证为湿瘀互结证慢性肾小球肾炎患者应用当归芍药散治疗的临床效果。方法分析对象来自2016年—2018年收治慢性肾小球肾炎且中医辨证为湿瘀互结证患者,在该群体中随机抽取80例并按每组40例分为对照组与观察组,对照组患者用西医对症干预手段,观察组联合中药当归芍药散。比较2种治疗方案下慢性肾小球肾炎患者病情控制情况。结果在病情控制有效率方面,对照组为75. 0%,观察组为92. 5%,组间数据有差异且具统计学意义(P <0. 05);相对于治疗前,患者血尿生化指标均有改善,治疗后观察组血尿生化指标所得数据优于对照组且有统计学意义(P <0. 05)。结论对于湿瘀互结证的慢性肾小球肾炎患者除了西医常规对症干预外,配合中药方剂当归芍药散治疗,从长远角度而言对于治疗的保障有更重要价值,值得推广。
Objective To understand the clinical effect of Danggui Shaoyao powder in the treatment of chronic glomerulonephritis with syndrome of stagnation of dampness and blood stasis. Methods Subjects of chronic glomerulonephritis with syndrome of stagnation of dampness and blood stasis from the hospital were selected. 80 patients were randomly divided into control group and observation group. The patients in the control group were treated with western medicine symptomatic intervention,and the observation group combined with Chinese medicine Danggui Shaoyao powder. The condition control of patients with chronic glomerulonephritis under two treatment plans was compared. Results In terms of disease control efficiency,the control group was 75. 0% and the observation group was 92. 5%. The data between the groups was statistically significant( P < 0. 05). Compared with before treatment,the biochemical indicators of hematuria were improved. After treatment,the data obtained from biochemical markers of hematuria in the observation group were better than those in the control group( P < 0. 05). Conclusion For patients with chronic glomerulonephritis with syndrome of stagnation of dampness and blood stasis,besides the conventional symptomatic intervention in western medicine,Treatment with Danggui Shaoyao Powder,it is of more important value for the protection of treatment in the long-term and worthy of promotion.
Objective To understand the clinical effect of Danggui Shaoyao powder in the treatment of chronic glomerulonephritis with syndrome of stagnation of dampness and blood stasis. Methods Subjects of chronic glomerulonephritis with syndrome of stagnation of dampness and blood stasis from the hospital were selected. 80 patients were randomly divided into control group and observation group. The patients in the control group were treated with western medicine symptomatic intervention,and the observation group combined with Chinese medicine Danggui Shaoyao powder. The condition control of patients with chronic glomerulonephritis under two treatment plans was compared. Results In terms of disease control efficiency,the control group was 75. 0% and the observation group was 92. 5%. The data between the groups was statistically significant( P < 0. 05). Compared with before treatment,the biochemical indicators of hematuria were improved. After treatment,the data obtained from biochemical markers of hematuria in the observation group were better than those in the control group( P < 0. 05). Conclusion For patients with chronic glomerulonephritis with syndrome of stagnation of dampness and blood stasis,besides the conventional symptomatic intervention in western medicine,Treatment with Danggui Shaoyao Powder,it is of more important value for the protection of treatment in the long-term and worthy of promotion.
引文
[1]刘志华,董彬,李颖,等.益气清利和络方联合离子导入治疗慢性肾小球肾炎气虚湿热瘀阻证临床研究[J].河南中医,2017,37(2):299-301.
[2]晋中恒,蒋松,王建华,等.健脾益肾清化法治疗慢性肾小球肾炎气虚湿热瘀阻证蛋白尿、血尿的临床疗效观察[J].河北中医,2017,39(6):819-824,843.
[3]薛东侠.中医辨证治疗慢性肾小球肾炎57例临床分析[J].临床研究,2016,24(4):139-140.
[4]张件云,李甜甜.肾疏宁加减配合虫类药治疗慢性肾小球肾炎30例临床观察[J].湖南中医杂志,2016,32(6):57-59.
[5]刘志华,董彬,李颖,等.益气清利和络方联合离子导入治疗慢性肾小球肾炎临床研究[J].中医学报,2016,31(11):1792-1795.
[6]蒋蕴智,冯松杰.加味柴苓汤联合黄葵胶囊治疗慢性肾小球肾炎湿热证临床观察[J].四川中医,2016,34(11):72-73.
[7]黄东华,何红涛,檀银川.肾络通汤对慢性肾小球肾炎患者TGF-β1,MMP-9和TMP-1因子的影响[J].中国实验方剂学杂志,2017,23(15):196-201.
[8]施进宝.肾炎康复片联合贝那普利治疗气阴两虚夹湿瘀型慢性肾小球肾炎的临床效果[J].海峡药学,2017,29(12):254-255.
[9]张昕贤,陈刚,曹和欣,等.黄芪消白颗粒治疗气虚湿淤型慢性肾小球肾炎蛋白尿随机对照研究[J].临床肾脏病杂志,2016,16(6):327-330.
[10]王雁,周乐,李伟.益肾化湿颗粒治疗慢性肾小球肾炎脾虚湿盛证的临床疗效[J].实用医学杂志,2016,32(16):2749-2751.
[11]彭国立.益肾化湿颗粒治疗慢性肾小球肾炎脾虚湿盛证的临床疗效[J].临床医药文献电子杂志,2018,5(5):177.
[12]曹自利.益阴清火汤治疗慢性肾小球肾炎血尿(阴虚火旺证)的临床研究[J].饮食保健,2016,3(21):97.
[13]袁慧,徐军建,季欣星,等.补脾益肾活血汤治疗慢性肾小球肾炎气虚血瘀证临床观察[J].现代中医药,2017,37(2):52-54.
[14]杨松涛.参芪地黄汤治疗慢性肾小球肾炎气阴两虚证的疗效观察[J].临床合理用药杂志,2016,9(20):53-54.
[15]姜新.强肾固精方治疗慢性肾小球肾炎的中医证候疗效观察[J].中国医药指南,2018,16(4):177.
[2]晋中恒,蒋松,王建华,等.健脾益肾清化法治疗慢性肾小球肾炎气虚湿热瘀阻证蛋白尿、血尿的临床疗效观察[J].河北中医,2017,39(6):819-824,843.
[3]薛东侠.中医辨证治疗慢性肾小球肾炎57例临床分析[J].临床研究,2016,24(4):139-140.
[4]张件云,李甜甜.肾疏宁加减配合虫类药治疗慢性肾小球肾炎30例临床观察[J].湖南中医杂志,2016,32(6):57-59.
[5]刘志华,董彬,李颖,等.益气清利和络方联合离子导入治疗慢性肾小球肾炎临床研究[J].中医学报,2016,31(11):1792-1795.
[6]蒋蕴智,冯松杰.加味柴苓汤联合黄葵胶囊治疗慢性肾小球肾炎湿热证临床观察[J].四川中医,2016,34(11):72-73.
[7]黄东华,何红涛,檀银川.肾络通汤对慢性肾小球肾炎患者TGF-β1,MMP-9和TMP-1因子的影响[J].中国实验方剂学杂志,2017,23(15):196-201.
[8]施进宝.肾炎康复片联合贝那普利治疗气阴两虚夹湿瘀型慢性肾小球肾炎的临床效果[J].海峡药学,2017,29(12):254-255.
[9]张昕贤,陈刚,曹和欣,等.黄芪消白颗粒治疗气虚湿淤型慢性肾小球肾炎蛋白尿随机对照研究[J].临床肾脏病杂志,2016,16(6):327-330.
[10]王雁,周乐,李伟.益肾化湿颗粒治疗慢性肾小球肾炎脾虚湿盛证的临床疗效[J].实用医学杂志,2016,32(16):2749-2751.
[11]彭国立.益肾化湿颗粒治疗慢性肾小球肾炎脾虚湿盛证的临床疗效[J].临床医药文献电子杂志,2018,5(5):177.
[12]曹自利.益阴清火汤治疗慢性肾小球肾炎血尿(阴虚火旺证)的临床研究[J].饮食保健,2016,3(21):97.
[13]袁慧,徐军建,季欣星,等.补脾益肾活血汤治疗慢性肾小球肾炎气虚血瘀证临床观察[J].现代中医药,2017,37(2):52-54.
[14]杨松涛.参芪地黄汤治疗慢性肾小球肾炎气阴两虚证的疗效观察[J].临床合理用药杂志,2016,9(20):53-54.
[15]姜新.强肾固精方治疗慢性肾小球肾炎的中医证候疗效观察[J].中国医药指南,2018,16(4):177.