高血糖症的无创功能医学检测价值探究
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摘要
研究无创功能医学检测手段对高血糖症的诊断价值。使用基于电阻抗成像技术的无创功能医学检测系统对清华大学退休教职工进行高血糖症健康风险筛查,比较无创功能医学检测系统与临床医学体检结果之间的差异。x~2检验结果显示,无创功能医学检测与临床医学体检对同一人群高血糖症的检测结果无显著性差异,P=0.629>0.05。AUC(ROC曲线下面积)=0.933>0.9,表明这一无创功能医学检测手段对高血糖症具有较高诊断价值,可用于高血糖症疾病风险筛查。由于该系统具有无创、快速、无辐射等特点,适用于大范围人群的血糖状况普查和健康风险分层筛查。
The diagnostic value of noninvasive functional medical testing in hyperglycemia is studied. The health risk of hyperglycemia among retired faculty members of Tsinghua University is screened by the noninvasive functional medical detection system based on electrical impedance tomography, and the differences between the results of non-invasive functional medical detection system and clinical medical examination are compared. The results of x~2 examination show that there is no significant difference between noninvasive functional medical examination and clinical medical examination for hyperglycemia in the same population(P=0.629>0.05). AUC(area under ROC curve) = 0.933 > 0.9 indicates that this noninvasive functional medical detection method has high diagnostic value for hyperglycemia and can be used for screening the disease risk of hyperglycemia. Because of its noninvasive, fast and nonradiation characteristics, the system is suitable for blood sugar screening and health risk stratified screening in a wide range of people.
The diagnostic value of noninvasive functional medical testing in hyperglycemia is studied. The health risk of hyperglycemia among retired faculty members of Tsinghua University is screened by the noninvasive functional medical detection system based on electrical impedance tomography, and the differences between the results of non-invasive functional medical detection system and clinical medical examination are compared. The results of x~2 examination show that there is no significant difference between noninvasive functional medical examination and clinical medical examination for hyperglycemia in the same population(P=0.629>0.05). AUC(area under ROC curve) = 0.933 > 0.9 indicates that this noninvasive functional medical detection method has high diagnostic value for hyperglycemia and can be used for screening the disease risk of hyperglycemia. Because of its noninvasive, fast and nonradiation characteristics, the system is suitable for blood sugar screening and health risk stratified screening in a wide range of people.
引文
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[2] 葛声,张片红,马爱勤,等.《中国2型糖尿病膳食指南》及解读[J].营养学报,2017,39(6):521-529.
[3] 林晓斐.国务院办公厅印发《中国防治慢性病中长期规划(2017—2025年)》[J].中医药管理杂志,2017(4):20.
[4] LINDLEY E J,BROWN B H,BARBER D C,et al.Monitoring body fluid distribution in microgravity using impedance tomography (APT (applied potential tomography))[J].Clin Phys Physiol Meas,1992,13(A):181-184.
[5] BAISCH F J,PETRAT G.Body fluid distribution in man in space and effect of lower body negative pressure treatment[J].The clinical investigator,1993,71(9):690-699.
[6] FRERICHS I,AMATO M B P,VAN KAAM A H,et al.Chest electrical impedance tomography examination,data analysis,terminology,clinical use and recommendations:consensus statement of the TRanslational EIT developmeNt stuDy group[J].Thorax,2016,72(1):83-93.
[7] TREPTE C J C,PHILLIPS C R,SOLà J,et al.Electrical impedance tomography (EIT) for quantification of pulmonary edema in acute lung injury[J].Critical Care,2015,20(1):18.
[8] HOLDER,DAVID S.Electrical impedance tomography:methods,history and applications[M].CRC Press,2004.
[9] BROWN B H.Electrical impedance tomography (EIT):a review[J].Journal of medical engineering & technology,2003,27(3):97-108.
[10] 徐桂芝,李颖.生物医学电阻抗成像技数[M].北京:机械工业出版社,2010.
[11] TIDSWELL T,GIBSON A,BAYFORD R H,et al.Three-dimensional electrical impedance tomography of human brain activity[J].NeuroImage,2001,13(2):283-294.
[12] ENGLAND W L.An exponential model used for optimal threshold selection on ROC curves[J].Medical Decision Making An International Journal of the Society for Medical Decision Making,1988,8(2):120.
[13] 程景炜,李灿萝,李志辉,等.运用 ROC 曲线评价能谱 CT 碘基物质对鼻咽癌的诊断价值[J].中国耳鼻咽喉颅底外科杂志,2017,23(1):49-53.
[14] 王英,李佩章,朱波,等.应用 Logistic 回归和 ROC 曲线综合评价肿瘤标志物联合检测对肺癌的诊断价值[J].中国现代医学杂志,2015,25(19):47-50.