血必净注射液不合理用药情况分析
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摘要
目的:分析我院血必净注射液的不合理用药情况,为临床合理用药提供参考。方法:采用回顾性研究方法,收集2016–2017年我院使用该药的病例,共计1078例,从用药科室、适应证、疗程、给药剂量、溶媒和溶媒量、给药频次、滴速、冲管等方面进行统计分析。结果:1078例中适应证不适宜53.15%、给药剂量不适宜0.93%、溶媒量不适宜25.32%、给药频次不适宜29.59%、未标注滴速98.42%、未冲管70.22%;用药科室主要集中在ICU、急诊病房及呼吸科等。结论:应严格按药品说明书规定使用血必净注射液并加强临床干预,促进合理用药。
Objective: To analyze the irrational application of Xuebijing injection in our hospital and provide references for rational drug use. Methods: Data of 1078 patients who were treated by Xuebijing injection in our hospital from 2016 to 2017 were collected and retrospectively analyzed in terms of the administration department, indication, course of treatment, dosages, solvent,amount of solvent, frequency of administration, drip speed, flushing or not, etc. Results: Among the 1078 cases, the proportion of cases with unreasonable indication, unreasonable dose, unreasonable amount of solvent, unreasonable frequency of administration,unmarked drip speed and unflushed tube was 53.15%, 0.93%, 25.32%, 29.59%, 98.42% and 70.22% respectively. Xuebijing injection was mainly used in the department of intensive care unit(ICU), emergency ward and respiratory department, etc. Conclusion:Xuebijing injection should be used strictly according to the drug instruction, and clinical intervention should be strengthened to promote rational drug use.
Objective: To analyze the irrational application of Xuebijing injection in our hospital and provide references for rational drug use. Methods: Data of 1078 patients who were treated by Xuebijing injection in our hospital from 2016 to 2017 were collected and retrospectively analyzed in terms of the administration department, indication, course of treatment, dosages, solvent,amount of solvent, frequency of administration, drip speed, flushing or not, etc. Results: Among the 1078 cases, the proportion of cases with unreasonable indication, unreasonable dose, unreasonable amount of solvent, unreasonable frequency of administration,unmarked drip speed and unflushed tube was 53.15%, 0.93%, 25.32%, 29.59%, 98.42% and 70.22% respectively. Xuebijing injection was mainly used in the department of intensive care unit(ICU), emergency ward and respiratory department, etc. Conclusion:Xuebijing injection should be used strictly according to the drug instruction, and clinical intervention should be strengthened to promote rational drug use.
引文
[1]尹航,谢程.111例氟喹诺酮类药品不良反应/事件临床分析[J].中国药物应用与监测,2017,14(3):163-165,182.
[2]李忻,于倩,王华.9441例注射用复方三维B(Ⅱ)的合理用药评价[J].中国药物应用与监测,2016,13(5):290-292.
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[7]周辉,刘峰.血必净注射液治疗慢性阻塞性肺疾病合并社区获得性肺炎的临床观察[J].中国药房,2017,28(14):1979-1981.
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[10]张曦,王绍安.血必净治疗老年重症肺炎的疗效及安全性[J].中国老年学杂志,2015,35(7):1785-1786.
[11]高鹏辉,胡占升.血必净与生长抑素联合治疗重症急性胰腺炎的临床疗效观察[J].中成药,2016,38(3):714-716.
[12]许睿婕,罗小星.Presepsin在评估血必净注射液抗炎疗效中的应用[J].中成药,2017,39(3):657-659.
[13]陆伟荣,吴先正.血必净对有机磷中毒血液灌流患者的治疗效果及作用机制[J].山东医药,2017,57(24):94-96.
[14]史晓峰,王勇强.血必净联合乌司他丁治疗百草枯中毒的效果观察[J].中国劳动卫生职业病杂志,2015,33(5):375-377.
[15]高声传,王童超.血必净注射液与多种溶媒配伍的稳定性研究[J].中国药物警戒,2016,13(3):180-182.
[2]李忻,于倩,王华.9441例注射用复方三维B(Ⅱ)的合理用药评价[J].中国药物应用与监测,2016,13(5):290-292.
[3]党安建,于倩,李忻.5554例注射用细辛脑的合理用药评价[J].中国药物应用与监测,2017,14(2):121-123.
[4]毕铁琳,于倩,谢程.8008例注射用丹参多酚酸盐的用药分析[J].中国药物应用与监测,2018,15(3):165-168.
[5]党安建,严明兰,于倩.19 468例果糖类注射液合理用药评价[J].中国药物应用与监测,2017,14(5):301-304.
[6]崔海珍,于倩,王华.2060例乙酰半胱氨酸注射液的用药评价[J].中国药物应用与监测,2018,15(2):99-102.
[7]周辉,刘峰.血必净注射液治疗慢性阻塞性肺疾病合并社区获得性肺炎的临床观察[J].中国药房,2017,28(14):1979-1981.
[8]杨晓琨,王敏.血必净治疗毛细血管渗漏综合征的临床研究[J].中国中西医结合急救杂志,2017,24(3):274-277,299.
[9]张国庆,龚晓亮,吴林,等.不同剂量血必净急诊治疗脓毒症的临床疗效[J].临床医学研究与实践,2018,3(21):38-39.
[10]张曦,王绍安.血必净治疗老年重症肺炎的疗效及安全性[J].中国老年学杂志,2015,35(7):1785-1786.
[11]高鹏辉,胡占升.血必净与生长抑素联合治疗重症急性胰腺炎的临床疗效观察[J].中成药,2016,38(3):714-716.
[12]许睿婕,罗小星.Presepsin在评估血必净注射液抗炎疗效中的应用[J].中成药,2017,39(3):657-659.
[13]陆伟荣,吴先正.血必净对有机磷中毒血液灌流患者的治疗效果及作用机制[J].山东医药,2017,57(24):94-96.
[14]史晓峰,王勇强.血必净联合乌司他丁治疗百草枯中毒的效果观察[J].中国劳动卫生职业病杂志,2015,33(5):375-377.
[15]高声传,王童超.血必净注射液与多种溶媒配伍的稳定性研究[J].中国药物警戒,2016,13(3):180-182.