自拟补脑柔肝健脾方治疗多发性抽动症临床观察
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摘要
目的:观察补脑柔肝健脾方治疗多发性抽动症的临床疗效。方法:选取45例多发性抽动综合征患儿,治疗以补脑柔肝健脾方,以12天为1疗程,共计5个疗程,应用统计学方法,采用疗前疗后自身对照,治疗不同疗程效果对照,并观察患儿的临床疗效。结果:抽动秽语综合征患儿经治疗后60天的总有效率为93.34%,24、36天疗后抽动频数与疗前有显著性差异(P<0.05),48、60天疗后抽动频数与疗前有极显著差异(P<0.01)。结论:程为平教授自拟补脑柔肝健脾方治疗小儿多发性抽动症,可有效减轻患儿症状,部分可治愈,值得在临床中推广。
Objective:To observe the clinical efficacy of using Self-made Bunao Rougan Jianpi Recipe in the treatment of Tourette syndrome.Methods:12 days as a course of treatment, a total of 5 courses of treatment for 45 children with Tourette syndrome were treated with Self-made Bunao Rougan Jianpi Recipe.The clinical effect of children was reflected by recording the tic frequency referring to the Yale degree of tic, variance analysis, matching rank and test statistical methods.Results:The results showed that the total effective rate of after treatment for 60 days was 93.34%.The tic frequency after treatment for 24 or 36 days was prominent compared with pre-treatment(P<0.05).The tic frequency after treatment for 48 or 60 days was extremely prominent compared with pre-treatment(P<0.01).Conclusion:Professor CHENG Weiping's prescription of t Self-made Bunao Rougan Jianpi Recipe is worth promoting that can reduce the symptom of the child effectively, partial can cure.
Objective:To observe the clinical efficacy of using Self-made Bunao Rougan Jianpi Recipe in the treatment of Tourette syndrome.Methods:12 days as a course of treatment, a total of 5 courses of treatment for 45 children with Tourette syndrome were treated with Self-made Bunao Rougan Jianpi Recipe.The clinical effect of children was reflected by recording the tic frequency referring to the Yale degree of tic, variance analysis, matching rank and test statistical methods.Results:The results showed that the total effective rate of after treatment for 60 days was 93.34%.The tic frequency after treatment for 24 or 36 days was prominent compared with pre-treatment(P<0.05).The tic frequency after treatment for 48 or 60 days was extremely prominent compared with pre-treatment(P<0.01).Conclusion:Professor CHENG Weiping's prescription of t Self-made Bunao Rougan Jianpi Recipe is worth promoting that can reduce the symptom of the child effectively, partial can cure.
引文
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[2] Robertson MM,Eapen V,Cavanna AE.The international prevalence,epidemiology,and clinical phenomenology of Tourette syndrome:a cross-culturalperspective[J].J Psychosomatic Res,2009,67(6):475～483
[3] Alves H L,Quagliato E M A B.The prevalence of tic disorders in children andadolescents in Brazil[J].Arquivos de neuro-psiquiatria,2014,72(12):942～948
[4] 中华医学会儿科学分会神经学组.儿童抽动障碍的诊断与治疗建议[J].中华儿科杂志,2013,51(1):72～75
[5] 汪受传,虞坚尔.中医儿科学[M].北京:中国中医药出版社,2012:173～177
[6] 刘智胜.儿童抽动障碍诊断要点[J].中国实用儿科杂志,2012,27(7):481～484
[7] 吴家骅.抽动障碍的分类、诊断及病情严重程度评估[J].中国实用儿科杂志,2002,17(4):196～197
[8] 钱红涛.基于关联规则和复杂熵聚类研究郑启仲教授治疗儿童抽动障碍用药规律[D].河南中医药大学,2016
[9] 杜沛霖,周雨晴,朱华.龟甲的研究进展[J].安徽农业科学,2014,42(32):11319～11320+11338
[10] 赵骞.益智仁健脑的神经保护作用药效物质筛选[D].西南交通大学,2017
[11] 陈萍,王培培,焦泽沼,等.益智仁的化学成分及药理活性研究进展[J].现代药物与临床,2013,28(04):617～623
[12] 陈颖,常琪,刘新民.天麻对中枢神经系统作用的研究进展[J].中草药,2007,38(6):10004～10006
[13] 刘晓芳,王素,梅卫利,等.健脾止动汤对 Tourette综合征模型鼠纹状体多巴胺转动蛋白表达的影响[J]中华行为医学与脑科学杂志,2012,21(3):225～227
[14] 雷载权.中药学[M].上海:上海科学技术出版社,1995,46.264～268.302
[15] 陈秀梅,郭敏玲,杨丽新.多发性抽动症发病相关因素的调查研究[J].中国中西医结合儿科学,2011,3(5):385～386