从肝论治女性更年期失眠的中医证候分布和用药规律的文献研究
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摘要
目的:通过分析中医药相关文献,探讨女性更年期失眠的中医证候分布规律和用药规律。方法:利用CNKI世纪期刊检索库对2007年6月-2016年6月中医药期刊文献所报道的女性更年期失眠相关文章进行检索,对其中涉及到的女性更年期失眠的证型、治则、用药规律进行统计分析。结果:共检出文献148篇,符合要求76篇;其中,有关中医证型47篇,有16种证候,以心肾不交证、肝肾阴虚、肝肾阴虚阳亢证等为主,与肝相关证候约占56.52%。基本证候分布以肝阴虚和肝阳亢盛等最为相关,总体与肝相关的最多,约占35.56%;有关治则76篇,提取基本治则20种,以滋肝养血、疏肝解郁和滋补肝阴等为主,以肝为关键的基本治则约占44.24%;涉及用药以白芍、酸枣仁、夜交藤等为主,前20位药物中归肝经的13味,约占70.58%。结论:"肝"在女性更年期失眠发病中较其他脏腑占有更重要地位。
Objective: To explore the distribution of traditional Chinese medicine(TCM) syndromes and regulation of drug use in climacteric insomnia in women by analyzing related TCM literatures. Methods: From June 2007 to June 2016, literatures related to female climacteric insomnia were searched using the CNKI database. The statistical analysis was made on the syndromes, rules and medication rules of female menopausal insomnia. Results: A total of 148 articles were identified, of which 76 were in accordance with the requirements. Forty-seven articles involved TCM syndromes, and there were 16 syndromes totally. The main syndromes were yin deficiency of liver and kidney, hyperactivity of yang due to yin deficiency of liver and kidney, and liver-related syndromes accounted for 56.52% of the total. The distribution of the basic syndromes was the most related to liveryin deficiency and liver-yang hyperactivity, and the liver-related was the most, which accounted for 35.56% of the total. Seventysix articles involved treatment rules, and the basic rule was extracted to 20. The main basic rules were nourishing liver and blood, dispersing stagnated liver qi for relieving qi stagnation, and nourishing liver yin. The liver-related basic rule accounted for 44.24% of the total. The main drugs were white peony root, spine date seed and tuber fleece flower stem, and the first 20 drugs which related to liver meridian accounted for about 70.58%. Conclusion: ‘Liver' occupies a more important position than other viscera in the onset of climacteric insomnia.
Objective: To explore the distribution of traditional Chinese medicine(TCM) syndromes and regulation of drug use in climacteric insomnia in women by analyzing related TCM literatures. Methods: From June 2007 to June 2016, literatures related to female climacteric insomnia were searched using the CNKI database. The statistical analysis was made on the syndromes, rules and medication rules of female menopausal insomnia. Results: A total of 148 articles were identified, of which 76 were in accordance with the requirements. Forty-seven articles involved TCM syndromes, and there were 16 syndromes totally. The main syndromes were yin deficiency of liver and kidney, hyperactivity of yang due to yin deficiency of liver and kidney, and liver-related syndromes accounted for 56.52% of the total. The distribution of the basic syndromes was the most related to liveryin deficiency and liver-yang hyperactivity, and the liver-related was the most, which accounted for 35.56% of the total. Seventysix articles involved treatment rules, and the basic rule was extracted to 20. The main basic rules were nourishing liver and blood, dispersing stagnated liver qi for relieving qi stagnation, and nourishing liver yin. The liver-related basic rule accounted for 44.24% of the total. The main drugs were white peony root, spine date seed and tuber fleece flower stem, and the first 20 drugs which related to liver meridian accounted for about 70.58%. Conclusion: ‘Liver' occupies a more important position than other viscera in the onset of climacteric insomnia.
引文
[1]钱丽旋,姜坤.从肝论治更年期综合征经验.江苏中医,1997,18(8):5
[2]GB/T16751.2-1997.中医临床诊疗术语·证候部分.北京:国家标准出版社,1997
[3]朱文锋.中医诊断学.北京:中国中医药出版社,2007
[4]姚乃礼.中医证候鉴别诊断学.北京:人民卫生出版社,2005
[5]董胜莲,刘瑞华,陈长香.22省(市)女性更年期综合征现状调查和影响因素分析.中国妇幼保健,2010,25(25):3604-3605
[6]张琳园.98例女性更年期抑郁症患者中医证候分布特点及病机的临床研究.北京:北京中医药大学,2013
[7]石玲,魏绍斌,孙海燕.围绝经期抑郁症的中西医研究进展.现代中西医结合杂志,2007,16(16):2319-2320
[8]康爱琴.更年期妇女健康状况及影响因素分析.中国妇幼保健,2013,28(2):283-286
[9]严晓丽,王翘楚.益肾平肝法治疗以失眠为主的更年期综合征42例疗效观察.四川中医,2008,26(2):74-75
[10]何静.中医疏肝解郁法治疗女性更年期失眠疗效分析.亚太传统医药,2014,8(10):58-59
[11]李坤.疏肝解郁治疗更年期不寐43例疗效观察.中医临床研究,2015,34(7):101-102
[2]GB/T16751.2-1997.中医临床诊疗术语·证候部分.北京:国家标准出版社,1997
[3]朱文锋.中医诊断学.北京:中国中医药出版社,2007
[4]姚乃礼.中医证候鉴别诊断学.北京:人民卫生出版社,2005
[5]董胜莲,刘瑞华,陈长香.22省(市)女性更年期综合征现状调查和影响因素分析.中国妇幼保健,2010,25(25):3604-3605
[6]张琳园.98例女性更年期抑郁症患者中医证候分布特点及病机的临床研究.北京:北京中医药大学,2013
[7]石玲,魏绍斌,孙海燕.围绝经期抑郁症的中西医研究进展.现代中西医结合杂志,2007,16(16):2319-2320
[8]康爱琴.更年期妇女健康状况及影响因素分析.中国妇幼保健,2013,28(2):283-286
[9]严晓丽,王翘楚.益肾平肝法治疗以失眠为主的更年期综合征42例疗效观察.四川中医,2008,26(2):74-75
[10]何静.中医疏肝解郁法治疗女性更年期失眠疗效分析.亚太传统医药,2014,8(10):58-59
[11]李坤.疏肝解郁治疗更年期不寐43例疗效观察.中医临床研究,2015,34(7):101-102