肠内、肠外营养支持治疗急性胰腺炎的疗效对比分析
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摘要
目的探讨肠内、肠外营养支持治疗急性胰腺炎的临床疗效差异。方法选取2014年1月～2017年12月我科收治的急性胰腺炎患者共128例,随机分为对照组(n=64)和试验组(n=64)。对照组使用常规治疗加肠外营养,试验组在对照组治疗基础上加用肠内营养支持治疗,比较两组的疗效。结果试验组患者的平均住院天数短于对照组,但不良反应发生率及预后转归两组无显著差异。治疗后显示试验组患者的淀粉酶、CRP、谷丙转氨酶水平明显低于对照组,血红蛋白及白蛋白水平高于对照组,差异均具有统计学意义(P<0.05),提示试验组的治疗效果优于对照组。结论联合应用肠内营养的支持治疗方法,能促进患者疾病恢复,在急性胰腺炎的临床治疗中效果显著。
Objective To investigate the clinical effect of enteral and parenteral nutrition support in the treatment of acute pancreatitis. Methods 128 patients with acute pancreatitis treated from Jan 2014 to Dec 2017 were randomly divided into the control group(n=64) and the experimental group(n=64). The control group accepted conventional therapy combined with parenteral nutrition, the experimental group accepted enteral nutrition support on the basis of the control group's treatment. Compared the efficacy of the two groups. Results The hospital stay in the experimental group was shorter than that in the control group. There were no significance in adverse reactions and prognosis between the two groups. The levels of serum amylase, CRP, ALT of patients in the experimental group were significantly lower than those in the control group. Hemoglobin(Hb) and albumin(ALB) in the experimental group were higher than those in the control group. The differences were statistically significant(P<0.05). Conclusion The combination of enteral and parenteral nutrition is beneficial to improve the nutritional status of the patients and promote the recovery of the disease. It is effective in the clinical treatment of acute pancreatitis.
Objective To investigate the clinical effect of enteral and parenteral nutrition support in the treatment of acute pancreatitis. Methods 128 patients with acute pancreatitis treated from Jan 2014 to Dec 2017 were randomly divided into the control group(n=64) and the experimental group(n=64). The control group accepted conventional therapy combined with parenteral nutrition, the experimental group accepted enteral nutrition support on the basis of the control group's treatment. Compared the efficacy of the two groups. Results The hospital stay in the experimental group was shorter than that in the control group. There were no significance in adverse reactions and prognosis between the two groups. The levels of serum amylase, CRP, ALT of patients in the experimental group were significantly lower than those in the control group. Hemoglobin(Hb) and albumin(ALB) in the experimental group were higher than those in the control group. The differences were statistically significant(P<0.05). Conclusion The combination of enteral and parenteral nutrition is beneficial to improve the nutritional status of the patients and promote the recovery of the disease. It is effective in the clinical treatment of acute pancreatitis.
引文
1王春友,李非,赵玉沛,等.急性胰腺炎诊治指南(2014)[J].临床外科杂志,2015,23(1):1-4
2冯晓玲,李可.肠内外营养支持治疗重症胰腺炎的疗效分析[J].中国社区医师(医学专业),2012,4(19):85-86
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4 Jin Z,Wang Z,Wang J.Early Enteral Nutrition Prevent Acute Pancreatitis From Deteriorating in Obese Patients[J].J Clin Gastroenterol,2018
5刘秋旻.早期肠内营养支持对重症胰腺炎患者的疗效分析[J].医药论坛杂志,2018,39(11):92-93
6陈洋,王永,刘向耿,等.肠内营养开始时间对重症急性胰腺炎疗效的影响[J].现代中西医结合杂志,2018,27(31):3470-3473
7刘华柱,章静.短肽制剂用于急性胰腺炎患者早期肠内营养支持的效果[J].医疗装备,2017,24:13-14
8 Endo A,Shiraishi A,Fushimi K,et al.Comparative effectiveness of elemental formula in the early enteral nutrition management of acute pancreatitis:a retrospective cohort study[J].Ann Intensive Care,2018,8(1):69
2冯晓玲,李可.肠内外营养支持治疗重症胰腺炎的疗效分析[J].中国社区医师(医学专业),2012,4(19):85-86
3 Pisters PW,Ranson JH.Nutritional support for acute pancreatitis[J].Surg Gynecol Obstet,1992,175(3):275-284
4 Jin Z,Wang Z,Wang J.Early Enteral Nutrition Prevent Acute Pancreatitis From Deteriorating in Obese Patients[J].J Clin Gastroenterol,2018
5刘秋旻.早期肠内营养支持对重症胰腺炎患者的疗效分析[J].医药论坛杂志,2018,39(11):92-93
6陈洋,王永,刘向耿,等.肠内营养开始时间对重症急性胰腺炎疗效的影响[J].现代中西医结合杂志,2018,27(31):3470-3473
7刘华柱,章静.短肽制剂用于急性胰腺炎患者早期肠内营养支持的效果[J].医疗装备,2017,24:13-14
8 Endo A,Shiraishi A,Fushimi K,et al.Comparative effectiveness of elemental formula in the early enteral nutrition management of acute pancreatitis:a retrospective cohort study[J].Ann Intensive Care,2018,8(1):69