妥布霉素滴眼液与氧氟沙星滴眼液治疗儿童急性结膜炎的临床比较研究
|
摘要
目的研究在儿童急性结膜炎的治疗中妥布霉素滴眼液与氧氟沙星滴眼液的临床效果。方法 84例急性结膜炎患儿,根据治疗方法不同分为对照组和观察组,每组42例。对照组患儿使用氧氟沙星滴眼液治疗,观察组患儿使用妥布霉素滴眼液治疗。对比两组患儿的临床效果及不良反应发生情况、复发情况。结果观察组患儿总有效率为95.2%,高于对照组的78.6%,差异具有统计学意义(P<0.05)。观察组患儿复发率为7.1%、不良反应发生率为2.4%,均低于对照组的26.2%、16.7%,差异具有统计学意义(P<0.05)。结论在儿童急性结膜炎治疗中,妥布霉素滴眼液的临床效果更为明显,且具有较高的安全性,适合应用。
Objective To study the clinical effect of tobramycin eye drops and ofloxacin eye drops in the treatment of children with acute conjunctivitis. Methods A total of 84 children with acute conjunctivitis were divided by different treatment methods into control group and observation group, with 42 cases in each group. The control group was treated with ofloxacin eye drops, and the observation group was treated with tobramycin eye drops. The clinical effect, occurrence of adverse reactions and recurrence condition in two groups was compared. Results The observation group had higher total effective rate as 95.2% than 78.6% in the control group, and the difference was statistically significant(P<0.05). The observation group had lower recurrence rate as 7.1% and incidence of adverse reactions as 2.4% than 26.2% and 16.7% in the control group, and their difference was statistically significant(P<0.05). Conclusion Tobramycin eye drops shows more obvious clinical effect in treating children with acute conjunctivitis with high safety. It is worthy of application.
Objective To study the clinical effect of tobramycin eye drops and ofloxacin eye drops in the treatment of children with acute conjunctivitis. Methods A total of 84 children with acute conjunctivitis were divided by different treatment methods into control group and observation group, with 42 cases in each group. The control group was treated with ofloxacin eye drops, and the observation group was treated with tobramycin eye drops. The clinical effect, occurrence of adverse reactions and recurrence condition in two groups was compared. Results The observation group had higher total effective rate as 95.2% than 78.6% in the control group, and the difference was statistically significant(P<0.05). The observation group had lower recurrence rate as 7.1% and incidence of adverse reactions as 2.4% than 26.2% and 16.7% in the control group, and their difference was statistically significant(P<0.05). Conclusion Tobramycin eye drops shows more obvious clinical effect in treating children with acute conjunctivitis with high safety. It is worthy of application.
引文
[1]王树民.氧氟沙星滴眼液治疗儿童急性结膜炎的疗效.北方药学, 2014, 26(1):24-25.
[2]金玉子. 0.5%左氧氟沙星眼液治疗儿童急性细菌性结膜炎的观察与防护措施.中国保健营养, 2012, 37(10):1379-1380.
[3]梁娟.不同眼药水滴眼间隔时间对急性结膜炎疗效的影响.医药前沿, 2017, 7(31):129.
[4]程彩珍.耳尖放血联合重组干扰素α1b滴眼液治疗急性结膜炎的临床研究.白求恩医学杂志, 2014, 23(1):91-92.
[5]刘海波,孙玲,马月仙,等.眼药水间隔时间对急性结膜炎患者疗效的影响.护士进修杂志, 2014, 15(7):662-663.
[6]尹丽娟,倪凤霞,赵书萍,等.两种滴眼液方法对小儿急性结膜炎效果的观察.中华现代护理杂志, 2013, 19(3):349-350.
[7]秦常军,于桂梅,梁丽娜.妥布霉素地塞米松滴眼液和更昔洛韦眼凝胶治疗102例急性结膜炎的临床观察.中国医疗前沿,2013, 31(23):86.
[8]陈陟,王达夫,吕维娜,等.用妥布霉素滴眼液与氧氟沙星滴眼液治疗儿童急性结膜炎的效果对比.当代医药论丛, 2016,14(12):175-176.
[9]邵蔚,张芳玲.左氧氟沙星滴眼液治疗儿童急性结膜炎172例疗效观察.内蒙古中医药, 2013, 32(5):87-88.
[10]李艳艳,邝平.小儿急性结膜炎采用两种滴眼液方法治疗的临床效果分析.中国医学创新, 2014(28):108-110.
[11]孙芳,张学辉. 0.5%左氧氟沙星滴眼液对儿童细菌性结膜炎的临床疗效观察.当代医学, 2009, 15(22):146.
[12]吴晓玉.氧氟沙星滴眼液治疗急性结膜炎的临床研究.现代中西医结合杂志, 2003, 12(10):1041.
[2]金玉子. 0.5%左氧氟沙星眼液治疗儿童急性细菌性结膜炎的观察与防护措施.中国保健营养, 2012, 37(10):1379-1380.
[3]梁娟.不同眼药水滴眼间隔时间对急性结膜炎疗效的影响.医药前沿, 2017, 7(31):129.
[4]程彩珍.耳尖放血联合重组干扰素α1b滴眼液治疗急性结膜炎的临床研究.白求恩医学杂志, 2014, 23(1):91-92.
[5]刘海波,孙玲,马月仙,等.眼药水间隔时间对急性结膜炎患者疗效的影响.护士进修杂志, 2014, 15(7):662-663.
[6]尹丽娟,倪凤霞,赵书萍,等.两种滴眼液方法对小儿急性结膜炎效果的观察.中华现代护理杂志, 2013, 19(3):349-350.
[7]秦常军,于桂梅,梁丽娜.妥布霉素地塞米松滴眼液和更昔洛韦眼凝胶治疗102例急性结膜炎的临床观察.中国医疗前沿,2013, 31(23):86.
[8]陈陟,王达夫,吕维娜,等.用妥布霉素滴眼液与氧氟沙星滴眼液治疗儿童急性结膜炎的效果对比.当代医药论丛, 2016,14(12):175-176.
[9]邵蔚,张芳玲.左氧氟沙星滴眼液治疗儿童急性结膜炎172例疗效观察.内蒙古中医药, 2013, 32(5):87-88.
[10]李艳艳,邝平.小儿急性结膜炎采用两种滴眼液方法治疗的临床效果分析.中国医学创新, 2014(28):108-110.
[11]孙芳,张学辉. 0.5%左氧氟沙星滴眼液对儿童细菌性结膜炎的临床疗效观察.当代医学, 2009, 15(22):146.
[12]吴晓玉.氧氟沙星滴眼液治疗急性结膜炎的临床研究.现代中西医结合杂志, 2003, 12(10):1041.