电针治疗糖尿病周围神经病变的研究进展
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摘要
电针及电针联合疗法对治疗糖尿病周围神经病有着显著作用。目前临床治疗除单纯电针外,常辅之以温针灸、耳穴及穴位注射。选穴主要以足三里、三阴交、合谷、曲池为主,且各穴之间存在着一定的腧穴配伍规律。同时大量动物实验研究证明,电针治疗糖尿病周围神经病变可能与镇痛机制有关。
Electroacupuncture and electroacupuncture combined therapy have significant effects on diabetic peripheral neuropathy. At present, clinical therapy includes needle warming moxibustion, auricular acupuncture and acupoint injection in addition to electroacupuncture. The clinical acupoints are mainly Zusanli(ST36), Sanyinjiao(SP6), Hegu(LI4) and Quchi(LI11), and there are certain rules of acupoints compatibility. At the same time, a large number of animal experiments have proved that electroacupuncture treatment of diabetic peripheral neuropathy may be related to the analgesic mechanism. However, its mechanism needs to be further explored to provide more evidence-based medical evidence for electroacupuncture treatment of diabetic peripheral neuropathy.
Electroacupuncture and electroacupuncture combined therapy have significant effects on diabetic peripheral neuropathy. At present, clinical therapy includes needle warming moxibustion, auricular acupuncture and acupoint injection in addition to electroacupuncture. The clinical acupoints are mainly Zusanli(ST36), Sanyinjiao(SP6), Hegu(LI4) and Quchi(LI11), and there are certain rules of acupoints compatibility. At the same time, a large number of animal experiments have proved that electroacupuncture treatment of diabetic peripheral neuropathy may be related to the analgesic mechanism. However, its mechanism needs to be further explored to provide more evidence-based medical evidence for electroacupuncture treatment of diabetic peripheral neuropathy.
引文
[1]苏玉珂.中医药治疗糖尿病周围神经病变的Meta分析[J].天津中医药, 2014, 31(6):335-339.
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[4]POP-BUSUI R, STEVENS M J, RAFFEL D M, et al. Effects of triple antioxidant therapy on measures of cardiovascular autonomic neuropathy and on myocardial blood flow in type 1diabetes:a randomised controlled trial[J]. Diabetologia, 2013,56(8):1835-1844.
[5]张雅琴,张玲,孟红果,等.“治痿独取阳明”——电针配合α-硫辛酸治疗2型糖尿病周围神经病变的临床观察[J].中国中医基础医学杂志, 2014, 20(8):1115-1116, 1122.
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[8]蚁淳,金真,冯细强,等.电针联合温针疗法治疗寒凝血瘀型糖尿病周围神经病变疗效观察[J].现代中西医结合杂志,2015, 24(16):1744-1746.
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[12]张燕.电针结合穴位注射治疗糖尿病周围神经病变的临床观察及对血Hcy水平的影响[D].武汉:湖北中医药大学, 2014.
[13]侯玉铎,陈妙玲,程艳婷,等.针灸治疗糖尿病周围神经病变的规律及皮肤感染相关性研究[J].中华医院感染学杂志, 2015, 25(2):387-389.
[14]尹真祯,杜琳,周宏,等.近十年针灸治疗2型糖尿病相关文献的经脉、穴位筛选[J].首都医药, 2012(4):19-22.
[15]王艳艳,麻东阳,于婷婷,等.针刺治疗糖尿病周围神经病变的腧穴配伍规律分析[J].中国中医基础医学杂志,2016, 22(9):1219-1222.
[16]王志福,杨意州,刘建波,等.电针对糖尿病周围神经病变大鼠脊髓脂氧合酶的影响[J].中国中医药信息杂志,2018, 25(5):56-60.
[17]王晓莉,覃建阳,尹昌浩,等.电针对糖尿病周围神经病大鼠坐骨神经Nrg1和ErbB2表达的影响[J].针灸临床杂志, 2014, 30(9):52-54.
[18]孙远征,吴迪,徐莺莺,等.电针对糖尿病周围神经病模型大鼠血清和坐骨神经SOD、MDA影响的研究[J].针灸临床杂志, 2009, 25(7):52-54.
[2]张永文,韩康生,程燕.糖尿病周围神经病变的中医病因病机及证治[J].吉林中医药, 2014, 34(6):561-564.
[3]张娇娇,王朝辉,逄紫千.针灸治疗糖尿病周围神经病变临床研究进展[J].长春中医药大学学报, 2012, 28(4):729.
[4]POP-BUSUI R, STEVENS M J, RAFFEL D M, et al. Effects of triple antioxidant therapy on measures of cardiovascular autonomic neuropathy and on myocardial blood flow in type 1diabetes:a randomised controlled trial[J]. Diabetologia, 2013,56(8):1835-1844.
[5]张雅琴,张玲,孟红果,等.“治痿独取阳明”——电针配合α-硫辛酸治疗2型糖尿病周围神经病变的临床观察[J].中国中医基础医学杂志, 2014, 20(8):1115-1116, 1122.
[6]叶翔,秦波,张玮,等.电针治疗糖尿病周围神经病变疗效评价及机制探讨[J].浙江中医杂志, 2013, 48(11):794-796.
[7]刘铭,马晖,富晓旭,等.电针结合甲钴胺片治疗糖尿病周围神经病变40例疗效观察[J].湖南中医杂志, 2015,31(9):88-90.
[8]蚁淳,金真,冯细强,等.电针联合温针疗法治疗寒凝血瘀型糖尿病周围神经病变疗效观察[J].现代中西医结合杂志,2015, 24(16):1744-1746.
[9]杨晓瑞.电针配合耳穴贴敷治疗糖尿病周围神经病变50例[J].内蒙古中医药, 2015, 34(10):69-70.
[10]何乐中.电针配合耳压治疗糖尿病周围神经病变疗效观察[J].上海针灸杂志, 2009, 28(2):100-101.
[11]金泽,张边防,尚丽霞,等.电针配合穴位注射治疗糖尿病周围神经病[J].中国针灸, 2011, 31(7):613-616.
[12]张燕.电针结合穴位注射治疗糖尿病周围神经病变的临床观察及对血Hcy水平的影响[D].武汉:湖北中医药大学, 2014.
[13]侯玉铎,陈妙玲,程艳婷,等.针灸治疗糖尿病周围神经病变的规律及皮肤感染相关性研究[J].中华医院感染学杂志, 2015, 25(2):387-389.
[14]尹真祯,杜琳,周宏,等.近十年针灸治疗2型糖尿病相关文献的经脉、穴位筛选[J].首都医药, 2012(4):19-22.
[15]王艳艳,麻东阳,于婷婷,等.针刺治疗糖尿病周围神经病变的腧穴配伍规律分析[J].中国中医基础医学杂志,2016, 22(9):1219-1222.
[16]王志福,杨意州,刘建波,等.电针对糖尿病周围神经病变大鼠脊髓脂氧合酶的影响[J].中国中医药信息杂志,2018, 25(5):56-60.
[17]王晓莉,覃建阳,尹昌浩,等.电针对糖尿病周围神经病大鼠坐骨神经Nrg1和ErbB2表达的影响[J].针灸临床杂志, 2014, 30(9):52-54.
[18]孙远征,吴迪,徐莺莺,等.电针对糖尿病周围神经病模型大鼠血清和坐骨神经SOD、MDA影响的研究[J].针灸临床杂志, 2009, 25(7):52-54.