石家庄市市售蜂花粉中金属元素含量测定和健康风险评价
|
摘要
目的通过对石家庄市市售蜂花粉中5种金属元素含量的测定,评价经由蜂花粉摄入的健康风险,监督食品安全,从而保证居民健康。方法蜂花粉样品经过预处理后,利用电感耦合等离子体原子发射光谱仪(ICP-AES)测定锰(Mn)、铝(Al)、铅(Pb)、铜(Cu)和铁(Fe)5种金属元素的含量,用靶标危害系数(THQ)和总危害指数(HI)对蜂花粉进行非致癌健康风险评价。结果部分样品Pb含量超出国家标准限定值(GB 2762-2017),Al和Fe在大部分样品中含量都比较高。Pb、Mn和Al对人体的潜在危险性较高,尤其在茶花蜂花粉中Mn占HI的贡献率高达81.45%,在松花蜂花粉中Pb的贡献率更高达82.62%。结论 5种金属元素的每日摄入量(EDI指数)均低于其参考暴露剂量(Rf D)。THQ和HI值均远远小于1.0,表明5种金属元素通过蜂花粉的摄入不会对人体造成非致癌风险。
Objective To determine the metal element content of commercially available bee pollen in Shijiazhuang City, and thus the health risk was evaluated and the food safety was monitored to ensure the health of residents. Methods Samples of bee pollen, after pretreatment and microwave digestion, the content of 5 metals,manganese(Mn), aluminum(Al), lead(Pb), copper(Cu) and iron(Fe) were measured by ICP-AES. The non-carcinogenic health risk of the bee powder was estimated by the target hazard coefficient(THQ) and the total hazard index(HI). Results The content of Pb in some samples exceeded the National Limit(GB 2762-2017), and Al and Fe were higher in most pollen samples. Pb, Mn and Al had higher potential risk to the human body,especially in Camellia pollen, the contribution rate of metal Mn to HI was up to 81.45%,and the Pb in pine pollen is as high as82.62%. Conclusion The daily intake(EDI index) of the 5 metals was lower than that of their reference exposure dose(RfD). THQ and HI values are far less than 1.0, indicating that the 5 kinds of metals elements cannot cause non-carcinogenic risk to humans through bee pollen intake.
Objective To determine the metal element content of commercially available bee pollen in Shijiazhuang City, and thus the health risk was evaluated and the food safety was monitored to ensure the health of residents. Methods Samples of bee pollen, after pretreatment and microwave digestion, the content of 5 metals,manganese(Mn), aluminum(Al), lead(Pb), copper(Cu) and iron(Fe) were measured by ICP-AES. The non-carcinogenic health risk of the bee powder was estimated by the target hazard coefficient(THQ) and the total hazard index(HI). Results The content of Pb in some samples exceeded the National Limit(GB 2762-2017), and Al and Fe were higher in most pollen samples. Pb, Mn and Al had higher potential risk to the human body,especially in Camellia pollen, the contribution rate of metal Mn to HI was up to 81.45%,and the Pb in pine pollen is as high as82.62%. Conclusion The daily intake(EDI index) of the 5 metals was lower than that of their reference exposure dose(RfD). THQ and HI values are far less than 1.0, indicating that the 5 kinds of metals elements cannot cause non-carcinogenic risk to humans through bee pollen intake.
引文
[1]曹蕾,魏永生,古元梓,等.茶花蜂花粉中常量、微量元素的分析测定[J].广东化工,2012,39(5):216-217.
[2]陈艳珍.蜂花粉醇提物对衰老小鼠学习、记忆及脑组织抗氧化能力的影响[J].中国畜牧兽医,2017,44(4):1022-1026.
[3]孙丽萍,田文礼,朱晓丽,等.蜂花粉功能食品的研究思路[J].中国蜂业,2006,57(10):39-40.
[4]程益清,夏晶,李丽敏,等.上海市2011~2015年保健食品中铅、砷、汞污染状况分析及评价[J].食品安全质量检测学报,2016,7(7):2587-2591.
[5]Zhou XP,Chen ZJ,Wang LY,et al.Analysis of food contamination caused by lead,cadmium,arsenic and aluminum in Shaoxing city,Zhejiang in 2005[J].Disease Surveillance,2008,23(2):100-106.
[6]Crapper DR,Krishnan SS,Dalton AJ.Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration[J].Science,1973,180(4085):511-513.
[7]任洁,杨丽琛.铁可耐受最高摄入量制定的研究进展[J].卫生研究,2013,42(2):323-326.
[8]方向,鲍远程,金珊,等.铜过量负荷对大鼠学习记忆功能的影响[J].中西医结合心脑血管病杂志,2013,11(10):1243-1244.
[9]张亮亮,程楠,王训.铜代谢机制及其对肝脏的毒性作用[J].胃肠病学,2016,(12):762-764.
[10]崔开媚,张俊清.饮水引起慢性锰中毒[J].广东微量元素科学,2000,7(10):40-41.
[11]庞霖霖,王进,黄婉媚,等.锰中毒性帕金森综合征大鼠脑中DMT1、FP1的研究[J].中华劳动卫生职业病杂志,2015,33(4):250-254.
[12]国家卫生和计划生育委员会,国家食品药品监督管理总局.GB2762-2017食品安全国家标准食品中污染物限量[S].北京:中国标准出版社,2017.
[13]赵黎芳,王支兰,杨胜琴,等.上海市某区居民粮食制品重金属铅、镉暴露评估[J].现代预防医学,2014,41(9):1581-1584.
[14]国家卫生和计划生育委员会.WS/T 578.3-2017中国居民膳食营养素参考摄入量第3部分:微量元素[S].北京:中国标准出版社,2017.
[15]中国营养学会[J].科协论坛,2014,(10):65.
[16]卢恒,徐宁,孟繁蕴.冬虫夏草重金属的含量测定和健康风险评价[J].环境化学,2017,36(5):1003-1008.
[17]周利,杨健,詹志来,等.不同产地黄连中重金属的含量测定及不同用药方式下黄连重金属的风险评估[J].药学学报,2018,53(3):432-438.
[2]陈艳珍.蜂花粉醇提物对衰老小鼠学习、记忆及脑组织抗氧化能力的影响[J].中国畜牧兽医,2017,44(4):1022-1026.
[3]孙丽萍,田文礼,朱晓丽,等.蜂花粉功能食品的研究思路[J].中国蜂业,2006,57(10):39-40.
[4]程益清,夏晶,李丽敏,等.上海市2011~2015年保健食品中铅、砷、汞污染状况分析及评价[J].食品安全质量检测学报,2016,7(7):2587-2591.
[5]Zhou XP,Chen ZJ,Wang LY,et al.Analysis of food contamination caused by lead,cadmium,arsenic and aluminum in Shaoxing city,Zhejiang in 2005[J].Disease Surveillance,2008,23(2):100-106.
[6]Crapper DR,Krishnan SS,Dalton AJ.Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration[J].Science,1973,180(4085):511-513.
[7]任洁,杨丽琛.铁可耐受最高摄入量制定的研究进展[J].卫生研究,2013,42(2):323-326.
[8]方向,鲍远程,金珊,等.铜过量负荷对大鼠学习记忆功能的影响[J].中西医结合心脑血管病杂志,2013,11(10):1243-1244.
[9]张亮亮,程楠,王训.铜代谢机制及其对肝脏的毒性作用[J].胃肠病学,2016,(12):762-764.
[10]崔开媚,张俊清.饮水引起慢性锰中毒[J].广东微量元素科学,2000,7(10):40-41.
[11]庞霖霖,王进,黄婉媚,等.锰中毒性帕金森综合征大鼠脑中DMT1、FP1的研究[J].中华劳动卫生职业病杂志,2015,33(4):250-254.
[12]国家卫生和计划生育委员会,国家食品药品监督管理总局.GB2762-2017食品安全国家标准食品中污染物限量[S].北京:中国标准出版社,2017.
[13]赵黎芳,王支兰,杨胜琴,等.上海市某区居民粮食制品重金属铅、镉暴露评估[J].现代预防医学,2014,41(9):1581-1584.
[14]国家卫生和计划生育委员会.WS/T 578.3-2017中国居民膳食营养素参考摄入量第3部分:微量元素[S].北京:中国标准出版社,2017.
[15]中国营养学会[J].科协论坛,2014,(10):65.
[16]卢恒,徐宁,孟繁蕴.冬虫夏草重金属的含量测定和健康风险评价[J].环境化学,2017,36(5):1003-1008.
[17]周利,杨健,詹志来,等.不同产地黄连中重金属的含量测定及不同用药方式下黄连重金属的风险评估[J].药学学报,2018,53(3):432-438.