尤瑞克林治疗穿支动脉梗死56例效果及对NHISS评分影响观察
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摘要
目的:观察尤瑞克林治疗穿支动脉梗死的效果及对NHISS评分影响。方法:选定笔者所在医院收治的112例穿支动脉梗死患者,研究时段2015年6月-2018年6月,分组原则以随机数字表法为主,分为对照组(56例,采纳临床常规治疗)、研究组(56例,在对照组基础上采纳尤瑞克林治疗),比较NHISS评分、Barthel指数、临床疗效。结果:研究组治疗后NHISS评分低于对照组,差异有统计学意义(P<0.05);研究组治疗后Barthel指数及临床总有效率均高于对照组,差异均有统计学意义(P<0.05)。结论:尤瑞克林可有效改善穿支动脉梗死患者神经功能缺损情况,提高生活自理能力,疗效显著,值得借鉴。
Objective:To observe the efficacy of Urinary Kallidinogenase in treatment of perforating arterial infarction and its effect on NHISS score.Method:A total of 112 patients with perforating arterial infarction admitted to our hospital were selected.During the study period from June 2015 to June 2018,the grouping principle was dominated by random digital table method,and were divided into the control group(56 patients,treated with clinical routine treatment),the study group(56 patients,treated with Urinary Kallidinogenase on the basis of the control group).The NHISS score,Barthel index,clinical efficacy were compared.Result:The NHISS score of the study group was significantly lower than that of the control group(P<0.05).The Barthel index and the total clinical effective rate in the study group were significantly higher than those in the control group(P<0.05).Conclusion:Urinary Kallidinogenase can effectively improve the neurological deficits in patients with perforating arterial infarction,improve the ability of self-care,and has significant curative effect.It is worth learning.
Objective:To observe the efficacy of Urinary Kallidinogenase in treatment of perforating arterial infarction and its effect on NHISS score.Method:A total of 112 patients with perforating arterial infarction admitted to our hospital were selected.During the study period from June 2015 to June 2018,the grouping principle was dominated by random digital table method,and were divided into the control group(56 patients,treated with clinical routine treatment),the study group(56 patients,treated with Urinary Kallidinogenase on the basis of the control group).The NHISS score,Barthel index,clinical efficacy were compared.Result:The NHISS score of the study group was significantly lower than that of the control group(P<0.05).The Barthel index and the total clinical effective rate in the study group were significantly higher than those in the control group(P<0.05).Conclusion:Urinary Kallidinogenase can effectively improve the neurological deficits in patients with perforating arterial infarction,improve the ability of self-care,and has significant curative effect.It is worth learning.
引文
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[12]王虹,金莎,李骏峰.丁苯酞联合尤瑞克林治疗急性脑梗死的临床研究[J].现代药物与临床,2016,31(5):640-644.
[2]刘鸣,谢鹏.神经内科学[M].北京:人民卫生出版社,2014.
[3]孟云,周宏斌,朱言亮.动脉溶栓术联用尤瑞克林对急性后循环脑梗死患者预后的影响[J].实用临床医药杂志,2014,18(9):51.
[4]王加良,张艳丽,邢健,等.尤瑞克林用于急性大脑中动脉脑梗死的疗效及对神经功能的影响[J].中国医院用药评价与分析,2017,17(2):170-172.
[5]王建平,李杰.尤瑞克林治疗急性脑梗死50例[J].中国药业,2015,24(21):233-234.
[6]崔自慧.尤瑞克林辅助治疗急性脑干梗死的疗效分析[J].中国实用神经疾病杂志,2017,20(9):119-121.
[7]史哲,卫景沛,张茗,等.尤瑞克林联合阿替普酶治疗超早期脑梗死的近期疗效观察[J].北京医学,2015,37(5):498-499.
[8]陆婉杏.尤瑞克林治疗脑梗死研究进展[J].泰山医学院学报,2017,38(3):358-360.
[9]沈卉君.尤瑞克林治疗脑梗死的临床效果分析[J].吉林医学,2015.36(14):3115-3116.
[10]陈家红.尤瑞克林治疗急性脑梗死的临床疗效观察[J].中国实用神经疾病杂志,2015,18(12):56-57.
[11]张申,刘喜灿,赵丹鹏,等.尤瑞克林联合阿司匹林治疗急性脑梗死的临床研究[J].中国临床药理学杂志,2016,32(16):1449-1452.
[12]王虹,金莎,李骏峰.丁苯酞联合尤瑞克林治疗急性脑梗死的临床研究[J].现代药物与临床,2016,31(5):640-644.