腹腔镜手术治疗急性结石性胆囊炎对炎性因子水平与胃肠功能的影响
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摘要
目的:探析急性结石性胆囊炎患者采取腹腔镜手术治疗对炎性因子及胃肠功能的影响。方法:本次研究74例急性结石性胆囊炎患者均为笔者所在医院2018年2-11月收治,根据先后入院时间分为两组,对照组(n=37)实施开腹手术,研究组(n=37)进行腹腔镜手术,统计各组胃肠功能指标及炎性因子水平。结果:研究组肛门排便时间、肛门排气时间及肠鸣音恢复时间均低于对照组,差异均有统计学意义(P<0.05);治疗前两组IL-6、TNF-α及hs-CRP水平比较差异无统计学意义(P>0.05),治疗后研究组均优于对照组,差异均有统计学意义(P<0.05)。结论:急性结石性胆囊炎疾病治疗过程中,通过腹腔镜手术有助于胃肠功能改善,减轻炎症病症。
Objective:To investigate the effect of laparoscopic cholecystectomy on inflammatory factors and gastrointestinal function in patients with acute calculous cholecystitis.Method:A total of 74 patients with acute calculous cholecystitis were admitted to our hospital from February to November 2018.According to the admission time,they were divided into two groups on average.The control group(n=37) underwent open surgery,and the research group(n=37) underwent laparoscopic surgery.The gastrointestinal function indexes and inflammatory factors in each group were counted.Result:The anal defecation time,anal exhaust time and intestinal sound recovery time in the study group were significantly lower than those in the control group(P<0.05).There was no significant difference in the levels of IL-6,TNF-α and hs-CRP between the two groups before treatment(P>0.05),but the study group was superior to the control group after treatment,and the difference was statistically significant(P<0.05).Conclusion:Laparoscopic cholecystectomy can improve gastrointestinal function and alleviate inflammation during the treatment of acute calculous cholecystitis.
Objective:To investigate the effect of laparoscopic cholecystectomy on inflammatory factors and gastrointestinal function in patients with acute calculous cholecystitis.Method:A total of 74 patients with acute calculous cholecystitis were admitted to our hospital from February to November 2018.According to the admission time,they were divided into two groups on average.The control group(n=37) underwent open surgery,and the research group(n=37) underwent laparoscopic surgery.The gastrointestinal function indexes and inflammatory factors in each group were counted.Result:The anal defecation time,anal exhaust time and intestinal sound recovery time in the study group were significantly lower than those in the control group(P<0.05).There was no significant difference in the levels of IL-6,TNF-α and hs-CRP between the two groups before treatment(P>0.05),but the study group was superior to the control group after treatment,and the difference was statistically significant(P<0.05).Conclusion:Laparoscopic cholecystectomy can improve gastrointestinal function and alleviate inflammation during the treatment of acute calculous cholecystitis.
引文
[1]欧阳钦,王三英,宋海良.腹腔镜胆囊切除术对结石性胆囊炎患者炎性因子及胃肠功能的影响[J].临床医学工程,2018,25(4):427-428.
[2]王峰,李正平,罗道蕴,等.LC治疗急性结石性胆囊炎合并胆汁性腹膜炎疗效观察[J].北华大学学报:自然科学版,2018,19(2):227-230.
[3]陈光裕,周小月,李鹏,等.腹腔镜胆囊切除术对急性结石性胆囊炎患者术后炎症因子及血清淀粉酶水平的影响[J].北华大学学报:自然科学版,2019,20(2):208-212.
[4]苏瑞洋,蒋元会.急性结石性胆囊炎患者应用开腹胆囊切除术和腹腔镜对CRP、胃肠功能的影响[J].中外医疗,2017,36(19):81-82.
[5]操志方.不同手术方式治疗老年急性结石性胆囊炎的临床效果与安全性对比[J].中外医学研究,2017,15(9):139-140.
[6]蔡伟,肖明华.腹腔镜胆囊切除术在急性胆囊炎治疗中的应用分析[J].中外医学研究,2017,15(24):146-147.
[7]陈坚.不同术式治疗80例急性结石性胆囊炎的效果及安全性评价[J].中外医学研究,2017,15(1):40-41.
[8]邝永龙,李铮宇,彭北生,等.腹腔镜手术治疗胃肠肿瘤的临床效果分析[J].中国医学创新,2017,14(3):66-68.
[9]郭名南,朱共元,辛小平,等.腹腔镜联合输尿管镜治疗肝胆管结石的临床分析[J].中国医学创新,2017,14(9):44-47.
[10]陈高民,区奕猛.腹腔镜解剖性肝左外叶切除术治疗肝内胆管结石的临床研究[J].中国医学创新,2017,14(4):53-56.
[11]牛四明.不同Calot三角解剖入路腹腔镜胆囊切除术治疗胆囊结石伴慢性胆囊炎患者疗效对比分析[J].实用肝脏病杂志,2018,21(3):447-450.
[12]陈亚红.微创胆囊切除术治疗老年慢性胆囊炎伴胆囊结石的临床疗效及对炎症因子的影响[J].中国老年学杂志,2017,37(15):3811-3813.
[13]吴兴才.腹腔镜胆囊切除术治疗急性结石性胆囊炎的效果分析[J].临床医学研究与实践,2017,2(25):69-70.
[14]孔令宇,刘春鹏.急性胆囊炎并结石行腹腔镜胆囊切除术后胆管损伤情况探析[J].中外医学研究,2018,16(14):153-155.
[15]马国华.腹腔镜胆囊手术与开腹胆囊手术用于胆囊结石患者的临床效果[J].中外医学研究,2017,15(32):20-21.
[2]王峰,李正平,罗道蕴,等.LC治疗急性结石性胆囊炎合并胆汁性腹膜炎疗效观察[J].北华大学学报:自然科学版,2018,19(2):227-230.
[3]陈光裕,周小月,李鹏,等.腹腔镜胆囊切除术对急性结石性胆囊炎患者术后炎症因子及血清淀粉酶水平的影响[J].北华大学学报:自然科学版,2019,20(2):208-212.
[4]苏瑞洋,蒋元会.急性结石性胆囊炎患者应用开腹胆囊切除术和腹腔镜对CRP、胃肠功能的影响[J].中外医疗,2017,36(19):81-82.
[5]操志方.不同手术方式治疗老年急性结石性胆囊炎的临床效果与安全性对比[J].中外医学研究,2017,15(9):139-140.
[6]蔡伟,肖明华.腹腔镜胆囊切除术在急性胆囊炎治疗中的应用分析[J].中外医学研究,2017,15(24):146-147.
[7]陈坚.不同术式治疗80例急性结石性胆囊炎的效果及安全性评价[J].中外医学研究,2017,15(1):40-41.
[8]邝永龙,李铮宇,彭北生,等.腹腔镜手术治疗胃肠肿瘤的临床效果分析[J].中国医学创新,2017,14(3):66-68.
[9]郭名南,朱共元,辛小平,等.腹腔镜联合输尿管镜治疗肝胆管结石的临床分析[J].中国医学创新,2017,14(9):44-47.
[10]陈高民,区奕猛.腹腔镜解剖性肝左外叶切除术治疗肝内胆管结石的临床研究[J].中国医学创新,2017,14(4):53-56.
[11]牛四明.不同Calot三角解剖入路腹腔镜胆囊切除术治疗胆囊结石伴慢性胆囊炎患者疗效对比分析[J].实用肝脏病杂志,2018,21(3):447-450.
[12]陈亚红.微创胆囊切除术治疗老年慢性胆囊炎伴胆囊结石的临床疗效及对炎症因子的影响[J].中国老年学杂志,2017,37(15):3811-3813.
[13]吴兴才.腹腔镜胆囊切除术治疗急性结石性胆囊炎的效果分析[J].临床医学研究与实践,2017,2(25):69-70.
[14]孔令宇,刘春鹏.急性胆囊炎并结石行腹腔镜胆囊切除术后胆管损伤情况探析[J].中外医学研究,2018,16(14):153-155.
[15]马国华.腹腔镜胆囊手术与开腹胆囊手术用于胆囊结石患者的临床效果[J].中外医学研究,2017,15(32):20-21.