泻痰清肺方辅助针对性护理对支气管哮喘患者心肺功能的影响研究
|
摘要
目的:观察针对性护理辅助泻痰清肺方对支气管哮喘患者肺功能的影响。方法:回顾性选取2015年4月至2017年2月我院收治的支气管哮喘患者98例,根据干预方法不同分为对照组和观察组。两组患者均给予泻痰清肺方治疗,对照组患者采用常规护理干预,观察组患者采用针对性护理干预,分析两组患者治疗后的临床效果。结果:治疗前,两组患者ACT评分比较无统计学差异(P>0.05)。治疗后,观察组患者ACT评分高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者FEV1、FEV1/FVC、PEF水平比较无统计学差异(P>0.05)。治疗后,观察组患者FEV1、FEV1/FVC、PEF水平高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者血清和痰液中IL-8、TNF-α、VEGF、EGF水平比较无统计学差异(P>0.05)。治疗后,观察组患者血清和痰液中IL-8、TNF-α水平低于对照组,但血清和痰液中VEGF、EGF水平与对照组比较,差异无统计学意义(P>0.05)。结论:针对性护理辅助泻痰清肺方治疗支气管哮喘疗效显著,可改善患者肺功能,减轻机体炎症反应。
Objective:To explore the effect of targeted nursing auxiliary Xietan Qingfei Reicpe on lung function of the patients with bronchial asthma. Methods:98 patients with bronchial asthma from April 2015 to February 2017 were retrospectively selected and divided into controlled group and observation group according to different intervention methods. The patients in both groups were treated with Xietan Qingfei Recipe,the patients in the controlled group were treated with routine nursing intervention,the patients in the observation group were treated with targeted nursing intervention,and the clinical effects of the two groups were analyzed. Results:Before treatment,there was no significant difference in ACT score between the two groups(P>0.05). After treatment,the ACT score in the observation group was higher than that in the controlled group(P<0.05). Before treatment,there was no significant difference in FEV1,FEV1/FVC,PEF levels between the two groups(P>0.05). After treatment,the level of FEV1,FEV1/FVC,PEF in the observation group was higher than that in the controlled group(P<0.05). Before treatment,the serum and sputum levels of IL-8,TNF-α,VEGFN-EGF were not found in the two groups. The difference was significant(P>0.05). After treatment,the levels of IL-8 TNF-αin serum and sputum in the observation group were lower than those in the controlled group,but there was no significant difference between the serum and sputum level of VEGF,EGF in the observation group and the controlled group(P>0.05). Conclusion:The therapeutic effect of Xiephan Qingfei Recipe on bronchial asthma is remarkable,which can improve the pulmonary function and alleviate the inflammatory reaction.
Objective:To explore the effect of targeted nursing auxiliary Xietan Qingfei Reicpe on lung function of the patients with bronchial asthma. Methods:98 patients with bronchial asthma from April 2015 to February 2017 were retrospectively selected and divided into controlled group and observation group according to different intervention methods. The patients in both groups were treated with Xietan Qingfei Recipe,the patients in the controlled group were treated with routine nursing intervention,the patients in the observation group were treated with targeted nursing intervention,and the clinical effects of the two groups were analyzed. Results:Before treatment,there was no significant difference in ACT score between the two groups(P>0.05). After treatment,the ACT score in the observation group was higher than that in the controlled group(P<0.05). Before treatment,there was no significant difference in FEV1,FEV1/FVC,PEF levels between the two groups(P>0.05). After treatment,the level of FEV1,FEV1/FVC,PEF in the observation group was higher than that in the controlled group(P<0.05). Before treatment,the serum and sputum levels of IL-8,TNF-α,VEGFN-EGF were not found in the two groups. The difference was significant(P>0.05). After treatment,the levels of IL-8 TNF-αin serum and sputum in the observation group were lower than those in the controlled group,but there was no significant difference between the serum and sputum level of VEGF,EGF in the observation group and the controlled group(P>0.05). Conclusion:The therapeutic effect of Xiephan Qingfei Recipe on bronchial asthma is remarkable,which can improve the pulmonary function and alleviate the inflammatory reaction.
引文
[1] 王晓强,刘亚宁,齐翠娟.自拟清肺化痰合剂联合针刺及罐疗对热哮证哮喘肺功能及免疫因子水平的影响[J].现代中西医结合杂志,2016,25(25):2765～2767
[2] 赵永.清肺化痰方治疗哮喘患儿的临床观察及肺功能评价[J].陕西中医,2017,38(2):215～216
[3] 黄南,王晓龙,李文静,等.泻痰清肺方对支气管哮喘患者血清TNF-α和IL-8水平的影响[J].陕西中医,2017,38(5):588～589
[4] 邹外龙,刘仲楠,周绍文.清肺定喘泻热法对呼吸机相关性重症肺炎(痰热壅肺型)肺功能、中医证候积分和炎症因子的影响[J].中国中医急症,2016,25(9):1809～1811
[5] 陈晓东,孙俊.清肺补肾化瘀法联合西医对COPD患者肺功能及锁链素水平的影响[J].陕西中医,2017,38(1):34～35
[6] 钟远芹,蓝伟峰.布地奈德联合沙丁胺醇治疗支气管哮喘的效果及对患者TGF-β1、CRP水平和肺功能的影响[J].广东医学,2016,37(6):915～917
[7] 李荣琳.清肺活血中药治疗支气管扩张急性加重期疗效及对MMP-9、TIMP-1水平的影响[J].现代中西医结合杂志,2017,26(35):3944～3946
[8] 陈序庚,杨晓红,王娜,等.清肺抑毒汤加减在病毒感染性肺炎患者中的疗效及对肺损伤的改善作用研究[J].中华医院感染学杂志,2017,27(23):5333～5336
[9] 翟玉云,魏文先,王杰.清肺平喘汤加减治疗急性发作期慢性阻塞性肺疾病痰热蕴肺证临床研究[J].中医学报,2017,32(11):2070～2073
[10] 孙建,任柏沉,杨帆,等.纤维支气管镜吸痰联合常规抗感染治疗对重症肺部感染患者肺功能及炎症状态的影响[J].海南医学院学报,2016,22(13):1373～1376
[11] 高占华,郭建恩,刘利蕊,等.自拟清肺化痰汤对支气管肺炎患者临床症状及炎性因子的影响[J].中药材,2016,39(10):2373～2375
[12] 刘莉,胡成平,李瑛,等.心理干预联合药物治疗对哮喘患者焦虑抑郁情绪及肺功能的影响[J].海南医学,2016,27(17):2783～2785
[13] 尹彦敏.老年支气管哮喘流行病学调查及强化护理干预措施探讨[J].西部中医药,2016,29(11):116～118
[14] 张旋.定喘汤加减联合西医治疗对支气管哮喘患者呼吸状态的影响观察[J].世界中西医结合杂志,2017,12(11):1558～1560
[15] 孙咏艳,蔡云,杨焕霞.集束化护理对氧驱动雾化给药治疗支气管哮喘患者的应用[J].实用临床医药杂志,2016,20(16):35～37
[2] 赵永.清肺化痰方治疗哮喘患儿的临床观察及肺功能评价[J].陕西中医,2017,38(2):215～216
[3] 黄南,王晓龙,李文静,等.泻痰清肺方对支气管哮喘患者血清TNF-α和IL-8水平的影响[J].陕西中医,2017,38(5):588～589
[4] 邹外龙,刘仲楠,周绍文.清肺定喘泻热法对呼吸机相关性重症肺炎(痰热壅肺型)肺功能、中医证候积分和炎症因子的影响[J].中国中医急症,2016,25(9):1809～1811
[5] 陈晓东,孙俊.清肺补肾化瘀法联合西医对COPD患者肺功能及锁链素水平的影响[J].陕西中医,2017,38(1):34～35
[6] 钟远芹,蓝伟峰.布地奈德联合沙丁胺醇治疗支气管哮喘的效果及对患者TGF-β1、CRP水平和肺功能的影响[J].广东医学,2016,37(6):915～917
[7] 李荣琳.清肺活血中药治疗支气管扩张急性加重期疗效及对MMP-9、TIMP-1水平的影响[J].现代中西医结合杂志,2017,26(35):3944～3946
[8] 陈序庚,杨晓红,王娜,等.清肺抑毒汤加减在病毒感染性肺炎患者中的疗效及对肺损伤的改善作用研究[J].中华医院感染学杂志,2017,27(23):5333～5336
[9] 翟玉云,魏文先,王杰.清肺平喘汤加减治疗急性发作期慢性阻塞性肺疾病痰热蕴肺证临床研究[J].中医学报,2017,32(11):2070～2073
[10] 孙建,任柏沉,杨帆,等.纤维支气管镜吸痰联合常规抗感染治疗对重症肺部感染患者肺功能及炎症状态的影响[J].海南医学院学报,2016,22(13):1373～1376
[11] 高占华,郭建恩,刘利蕊,等.自拟清肺化痰汤对支气管肺炎患者临床症状及炎性因子的影响[J].中药材,2016,39(10):2373～2375
[12] 刘莉,胡成平,李瑛,等.心理干预联合药物治疗对哮喘患者焦虑抑郁情绪及肺功能的影响[J].海南医学,2016,27(17):2783～2785
[13] 尹彦敏.老年支气管哮喘流行病学调查及强化护理干预措施探讨[J].西部中医药,2016,29(11):116～118
[14] 张旋.定喘汤加减联合西医治疗对支气管哮喘患者呼吸状态的影响观察[J].世界中西医结合杂志,2017,12(11):1558～1560
[15] 孙咏艳,蔡云,杨焕霞.集束化护理对氧驱动雾化给药治疗支气管哮喘患者的应用[J].实用临床医药杂志,2016,20(16):35～37