高通量血液透析与血液透析滤过在尿毒症心衰患者中的应用效果对比观察
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摘要
目的对比观察高通量血液透析与血液透析滤过在尿毒症心衰患者中的应用效果。方法收集本院2016年7月～2017年9月收治的60例尿毒症心衰患者进行分组,依据数字表法分为对照组和治疗组,每组30例,分别进行血液透析滤过治疗和高通量血液透析治疗,比较治疗前后血肌酐(SCr)、甲状旁腺激素(PTH)、β2-微球蛋白(β2-MG)变化及临床疗效。结果两组治疗后的SCr、PTH、β2-MG均明显低于治疗前,组间展开比较,治疗组PTH、β2-MG均低于对照组(P<0.05),两组SCr比较差异无统计学意义;对两组治疗总有效率进行比较,治疗组显著高于对照组,组间差异具有统计学意义(P<0.05)。结论与血液透析滤过相比,高通量血液透析治疗尿毒症心衰效果更为确切,可作为优先选择的治疗方案全面推广。
Objective To observe the effect of high-flux hemodialysis and hemodiafiltration on uremic patients with heart failure.Methods Sixty patients with uremic heart failure who were admitted to our hospital from July 2016 to September 2017 were divided into a control group and a treatment group according to the digital table method. Thirty patients in each group were treated with hemodiafiltration. And highthroughput hemodialysis treatment, compared before and after treatment of serum creatinine(SCr), parathyroid hormone(PTH), β2-microglobulin(β2-MG) changes and clinical efficacy. Results After treatment, the SCr, PTH, and β2-MG levels were significantly lower than before treatment. The comparison between the two groups showed that the PTH and β2-MG in the treatment group were lower than those in the control group(P<0.05).There was no significant difference between the two groups in SCr. The total effective rate of the two groups was compared. The treatment group was significantly higher than the control group. There was a significant difference between the two groups(P<0.05). Conclusion Compared with hemodiafiltration, the effect of high-flux hemodialysis on uremic heart failure is more accurate and can be used as a preferred treatment plan.
Objective To observe the effect of high-flux hemodialysis and hemodiafiltration on uremic patients with heart failure.Methods Sixty patients with uremic heart failure who were admitted to our hospital from July 2016 to September 2017 were divided into a control group and a treatment group according to the digital table method. Thirty patients in each group were treated with hemodiafiltration. And highthroughput hemodialysis treatment, compared before and after treatment of serum creatinine(SCr), parathyroid hormone(PTH), β2-microglobulin(β2-MG) changes and clinical efficacy. Results After treatment, the SCr, PTH, and β2-MG levels were significantly lower than before treatment. The comparison between the two groups showed that the PTH and β2-MG in the treatment group were lower than those in the control group(P<0.05).There was no significant difference between the two groups in SCr. The total effective rate of the two groups was compared. The treatment group was significantly higher than the control group. There was a significant difference between the two groups(P<0.05). Conclusion Compared with hemodiafiltration, the effect of high-flux hemodialysis on uremic heart failure is more accurate and can be used as a preferred treatment plan.
引文
[1]王晓文.维持性透析终末期肾功能衰竭患者经高通量血液透析疗效观察[J/OL].当代医学,201824(13):142-144
[2]薛茹.高通量血液透析对糖尿病肾病患者炎性因子及肾功能的影响[J].社区医学杂志,2018,16(5):20-22.
[3]钟耀翠.慢性肾衰竭尿毒症应用高通量血液透析与血液透析滤过进行治疗的效果比较[J].中国医学创新,2018,15(7):8-12.
[4]赵婷.高通量血液透析和常规血液透析的临床疗效比较[J].当代医学,2018,24(5):82-83.
[5]张洪源,林小堃.高通量血液透析联合尿毒清对老年终末期肾病患者细胞免疫的影响[J].实用医学杂志,2018,34(2):273-276.
[6]马志宏,胡文博,贾顺莲,等.高通量与低通量血液透析对糖尿病肾病透析患者氧化应激、细胞免疫功能和微炎症状态的影响[J].现代生物医学进展,2017,17(30):5963-5966.
[7]顾宏晨,卞蓉蓉,薛贤,等.高通量血液滤器在尿毒症患者透析中的应用[J].中国医学物理学杂志,2017,34(08):855-859.
[8]温玉.高通量血液透析联合低钙透析液与普通透析对尿毒症病人皮肤瘙痒评分及血生化指标的影响对比[J].安徽医药,2017,21(3):496-500.
[9]李耀红,李群,罗海青.高通量血液透析与血液透析滤过对慢性肾衰竭尿毒症患者的透析效果比较[J].中外医学研究,2017,15(2):45-47.
[10]陆明.常规血液透析联合血液透析滤过、高通量血液透析治疗尿毒症临床对比[J].中国实用医药,2016,11(26):148-150.
[11]刘颐业.慢性肾衰竭尿毒症患者血液透析滤过与高通量血液透析透析效果比较[J].现代诊断与治疗,2014,25(18):4271-4272.
[2]薛茹.高通量血液透析对糖尿病肾病患者炎性因子及肾功能的影响[J].社区医学杂志,2018,16(5):20-22.
[3]钟耀翠.慢性肾衰竭尿毒症应用高通量血液透析与血液透析滤过进行治疗的效果比较[J].中国医学创新,2018,15(7):8-12.
[4]赵婷.高通量血液透析和常规血液透析的临床疗效比较[J].当代医学,2018,24(5):82-83.
[5]张洪源,林小堃.高通量血液透析联合尿毒清对老年终末期肾病患者细胞免疫的影响[J].实用医学杂志,2018,34(2):273-276.
[6]马志宏,胡文博,贾顺莲,等.高通量与低通量血液透析对糖尿病肾病透析患者氧化应激、细胞免疫功能和微炎症状态的影响[J].现代生物医学进展,2017,17(30):5963-5966.
[7]顾宏晨,卞蓉蓉,薛贤,等.高通量血液滤器在尿毒症患者透析中的应用[J].中国医学物理学杂志,2017,34(08):855-859.
[8]温玉.高通量血液透析联合低钙透析液与普通透析对尿毒症病人皮肤瘙痒评分及血生化指标的影响对比[J].安徽医药,2017,21(3):496-500.
[9]李耀红,李群,罗海青.高通量血液透析与血液透析滤过对慢性肾衰竭尿毒症患者的透析效果比较[J].中外医学研究,2017,15(2):45-47.
[10]陆明.常规血液透析联合血液透析滤过、高通量血液透析治疗尿毒症临床对比[J].中国实用医药,2016,11(26):148-150.
[11]刘颐业.慢性肾衰竭尿毒症患者血液透析滤过与高通量血液透析透析效果比较[J].现代诊断与治疗,2014,25(18):4271-4272.