门诊1040例儿童H.pylori感染状况分析
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摘要
目的分析新疆维吾尔自治区人民医院门诊就诊的儿童H. pylori感染状况,为H. pylori相关疾病的防治提供建议。方法回顾性分析2017年4月-2018年4月,行13C尿素呼气试验的儿童资料共1040例。按不同年龄段分为2组,分别为学龄前组和学龄后组,采用分参数检验进行统计分析。结果门诊儿童总的H. pylori感染率为48.9%,男性和女性之间比较,差异无统计学意义(X~2=0.6,P> 0.05);学龄后组较学龄前组的H. pylori感染率高,两组具有统计学差异(X~2=429.1, P <0.01);不同民族之间,维吾尔族H. pylori感染率最高,各组间比较,差异具有统计学意义(X~2=450.5,P <0.01)。结论 H. pylori的感染率随年龄的增加而增加,维吾尔族儿童的H. pylori感染率高,应在学龄前以科普形式讲述H. pylori的预防。
Objective To analyze the prevalence of H.pylori infection in children outpatients at people's Hospital in Xinjiang Uygur Autonomous Region, and to provide suggestions for prevention and treatment of H. pylori related diseases. Methods A total of 1040 children with 13 C urea breath test from April 2017 to April 2018 were retrospectively analyzed. According to different age groups, they were divided into 2 groups, preschool group and school age group. The statistical analysis was carried out by Nonparametric test. Result The total H. pylori infection rate in out-patient children was 48.9%, and there was no significant difference between male and female(X~2 =0.6, P > 0.05). The infection rate of H. pylori in the school age group was higher than that of the preschool group, with statistically significance(X~2 = 429.1, P < 0.01). Among different nationalities, H. pylori infection rate in Uygur ethnic group was the highest compared with each group, and the difference had statistically significant.(X~2 = 450.5,P < 0.01). Conclusion The infection rate of H. pylori increases with the increase of age. The infection rate of H. pylori in Uygur ethnic group is highest. The prevention of H. pylori should be described in the form of popular science in preschoolers.
Objective To analyze the prevalence of H.pylori infection in children outpatients at people's Hospital in Xinjiang Uygur Autonomous Region, and to provide suggestions for prevention and treatment of H. pylori related diseases. Methods A total of 1040 children with 13 C urea breath test from April 2017 to April 2018 were retrospectively analyzed. According to different age groups, they were divided into 2 groups, preschool group and school age group. The statistical analysis was carried out by Nonparametric test. Result The total H. pylori infection rate in out-patient children was 48.9%, and there was no significant difference between male and female(X~2 =0.6, P > 0.05). The infection rate of H. pylori in the school age group was higher than that of the preschool group, with statistically significance(X~2 = 429.1, P < 0.01). Among different nationalities, H. pylori infection rate in Uygur ethnic group was the highest compared with each group, and the difference had statistically significant.(X~2 = 450.5,P < 0.01). Conclusion The infection rate of H. pylori increases with the increase of age. The infection rate of H. pylori in Uygur ethnic group is highest. The prevention of H. pylori should be described in the form of popular science in preschoolers.
引文
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[2]李红艳,邓涛,占义军,等. 3368例武汉市儿童幽门螺杆菌感染的临床分析[J].胃肠病学和肝病学杂志, 2012, 21(1):63-65.
[3]陈凤,刘文莉,耿岚岚,等.儿童消化性溃疡病140例临床分析[J].中国实用儿科杂志, 2015, 30(5):124-127.
[4]Wong BC, Lam SK, Wong WM, et al. Helicobacter pylori erad?ication to preventgastric cancer in a high-risk region of China:a randomized controlled trial[J]. JA-MA, 2004, 291(2):187-194.
[5]Dohil R, Hassall E. Peptic ulcer disease in children[J]. Bail?lieres Best Pract ResClin Gastroenterol, 2000, 14(1):53-73.
[6]左婷婷,郑荣寿,曾红梅,第.中国胃癌流行病学现状[J].中国肿瘤临床,2017, 44(1):52-58.
[7]卢乐声,徐智芳,白星,等.嘉兴地区学龄儿童幽门螺杆菌感染状况和危险因素及耐药性分析[J].中国妇幼保健, 2018, 33(2):338-340.
[8]韩一凡,于新娟,王莉莉,等.中国幽门螺杆菌耐药情况研究[J].胃肠病学和肝病学杂志, 2017, 26(6):664-669.
[9]姚晨,王燕.乌市某银行2301名健康体检人群幽门螺杆菌感染状况调查[J].新疆医学, 2017, 47(11):1279-1280.