胃腺癌组织分化相关蛋白质的鉴定筛选
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摘要
目的分析胃腺癌组织分化相关蛋白质的鉴定筛选。方法结合目前相关参考文献资料,总结分析胃腺癌组织分析相关蛋白质在胃腺癌组织中的应用变化。结果相关蛋白质在胃腺癌患者临床发生中具有直接参与。结论加强胃腺癌组织分化相关蛋白质鉴定筛选,能够提高胃腺癌患者早期诊断准确率和治疗有效性。
Objective Identification and analysis of screening of gastric cancer tissue differentiation associated protein. Methods Combined with the current relevant references, summarizing and analyzing the changes of gastric adenocarcinoma tissue analysis and application of related protein in gastric carcinoma tissues. Results Related proteins directly involved in clinical patients with gastric adenocarcinoma. Conclusion Strengthen gastric adenocarcinoma tissue differentiation related protein identification and selection, to improve the early diagnosis of gastric cancer patients the accuracy and effectiveness of treatment.
Objective Identification and analysis of screening of gastric cancer tissue differentiation associated protein. Methods Combined with the current relevant references, summarizing and analyzing the changes of gastric adenocarcinoma tissue analysis and application of related protein in gastric carcinoma tissues. Results Related proteins directly involved in clinical patients with gastric adenocarcinoma. Conclusion Strengthen gastric adenocarcinoma tissue differentiation related protein identification and selection, to improve the early diagnosis of gastric cancer patients the accuracy and effectiveness of treatment.
引文
[1]王伟平,刘池波.胃腺癌血清蛋白质标志物的筛选及鉴定[J].中国病理生理杂志,2012,28(2):274-280.
[2]宋衍燕,赵飞,肖迪,等.幽门螺杆菌与胃上皮细胞不同作用时间点蛋白质组的差异分析[J].世界华人消化杂志,2008,16(12):1260-1265.
[3]连海峰,吴小翎.神经纤毛蛋白1基因RNA干扰质粒对胃腺癌细胞SGC7901增殖和凋亡的影响[J].中国生物制品学杂志,2010,23(11):1190-1192+1197.
[4]刘羽,李勇,檀碧波,等.比较蛋白质组学技术鉴定和筛选胃腺癌组织分化相关蛋白质[J].中华实验外科杂志,2012,29(3):126-127.
[5]金治全,闫石,仇灏,等.人胃癌细胞株SGC-7901蛋白质组双向电泳图谱的建立及优化[J].苏州大学学报(医学版),2009,29(5):818-820.
[6]陈茉,丁士刚,刘琳娜,等.胃腺癌伴淋巴结转移的蛋白质组学分析[J].中国微创外科杂志,2012,12(4):359-363.
[7]徐振,徐松辉,晏光荣.运用亚细胞蛋白质组学方法发现胃腺癌潜在标志物UCHL1[J].中国病理生理杂志,2010,26(12):2358-2362.
[8]张志强,李茂玉,张桂英,等.激光捕获显微切割技术结合18O标记定量蛋白质组技术在胃癌标志物筛查中的应用研究[J].生物化学与生物物理进展,2009,26(3):311-322.
[9]Sward K,Dreja K,Susnjar M,et al.Inhibition of Rhoassociated kinase blocks agonist-induced Ca2+sensitization of myosin phosphorylation and force in guinea-pig ileum J Physiol,2000,522:33.
[10]马艳华,史玲,苏琦.LIM激酶与肿瘤[J].国际病理科学与临床杂志,2009,29(6):490-494.
[11]Scott R W,Olson M F.LIM kinases:function,regulation and association with human disease[J].J Mol Med,2007,85(6):555-568.
[12]Xu X,Johnson P,Mueller S C.Breast cancer cell covement:imaging invadopodia by TIRF and IRM microscopy[J].Methods Mol Biol,2009,571:209-225.
[2]宋衍燕,赵飞,肖迪,等.幽门螺杆菌与胃上皮细胞不同作用时间点蛋白质组的差异分析[J].世界华人消化杂志,2008,16(12):1260-1265.
[3]连海峰,吴小翎.神经纤毛蛋白1基因RNA干扰质粒对胃腺癌细胞SGC7901增殖和凋亡的影响[J].中国生物制品学杂志,2010,23(11):1190-1192+1197.
[4]刘羽,李勇,檀碧波,等.比较蛋白质组学技术鉴定和筛选胃腺癌组织分化相关蛋白质[J].中华实验外科杂志,2012,29(3):126-127.
[5]金治全,闫石,仇灏,等.人胃癌细胞株SGC-7901蛋白质组双向电泳图谱的建立及优化[J].苏州大学学报(医学版),2009,29(5):818-820.
[6]陈茉,丁士刚,刘琳娜,等.胃腺癌伴淋巴结转移的蛋白质组学分析[J].中国微创外科杂志,2012,12(4):359-363.
[7]徐振,徐松辉,晏光荣.运用亚细胞蛋白质组学方法发现胃腺癌潜在标志物UCHL1[J].中国病理生理杂志,2010,26(12):2358-2362.
[8]张志强,李茂玉,张桂英,等.激光捕获显微切割技术结合18O标记定量蛋白质组技术在胃癌标志物筛查中的应用研究[J].生物化学与生物物理进展,2009,26(3):311-322.
[9]Sward K,Dreja K,Susnjar M,et al.Inhibition of Rhoassociated kinase blocks agonist-induced Ca2+sensitization of myosin phosphorylation and force in guinea-pig ileum J Physiol,2000,522:33.
[10]马艳华,史玲,苏琦.LIM激酶与肿瘤[J].国际病理科学与临床杂志,2009,29(6):490-494.
[11]Scott R W,Olson M F.LIM kinases:function,regulation and association with human disease[J].J Mol Med,2007,85(6):555-568.
[12]Xu X,Johnson P,Mueller S C.Breast cancer cell covement:imaging invadopodia by TIRF and IRM microscopy[J].Methods Mol Biol,2009,571:209-225.