咽喉反流性疾病女性患者基频相关参数的特征
|
摘要
目的通过声学客观测量的方法研究咽喉反流性疾病(LPRD)对女性患者基频相关参数的影响。方法选取2015年6月～2018年3月厦门市妇幼保健院收治的75例LPRD女性患者作为试验组,随机选取85例无明显嗓音疾患的正常女性为健康对照组,采用XION DIVAS嗓音测试分析系统对2组的基频、基频标准差、最大基频、最小基频与基频微扰进行测试并比较。结果实验组的基频为(236. 41±27. 22) Hz,低于对照组的(245. 94±29. 13) Hz;实验组的基频微扰为0. 71±0. 37,高于对照组的0. 58±0. 33。这2项参数在2组间的差异具有统计学意义,其余3项参数未见明显差异。结论咽喉反流会影响女性的基频和基频微扰。
Objective To assess the parameters of the fundamental frequency in general female population and in patients with laryngopharyngeal reflux disease( LPRD) by using acoustic analysis method. Methods Seventy-five female patients with LPRD were chosen as the treatment group and 85 female healthy people as the control group. The XION DIVAS acoustic analysis software was used to measure the sustained vowel signals of the treatment group and the control group. The recorded parameters were as follow: fundamental frequency( F0),standard deviation of F0,maximum F0,minimum F0 and jitter. Results The mean fundamental frequency in the treatment group was 236. 41 ±27. 22 Hz and in the control group was 245. 94 ± 29. 13 Hz( P < 0. 05). The jitter in the treatment group was 0. 71 ±0. 37 and in the control group was 0. 58 ± 0. 33( P < 0. 05). The other three parameters had no significant changes.Conclusions Laryngopharyngeal reflux could influence F0 and jitter in female patients.
Objective To assess the parameters of the fundamental frequency in general female population and in patients with laryngopharyngeal reflux disease( LPRD) by using acoustic analysis method. Methods Seventy-five female patients with LPRD were chosen as the treatment group and 85 female healthy people as the control group. The XION DIVAS acoustic analysis software was used to measure the sustained vowel signals of the treatment group and the control group. The recorded parameters were as follow: fundamental frequency( F0),standard deviation of F0,maximum F0,minimum F0 and jitter. Results The mean fundamental frequency in the treatment group was 236. 41 ±27. 22 Hz and in the control group was 245. 94 ± 29. 13 Hz( P < 0. 05). The jitter in the treatment group was 0. 71 ±0. 37 and in the control group was 0. 58 ± 0. 33( P < 0. 05). The other three parameters had no significant changes.Conclusions Laryngopharyngeal reflux could influence F0 and jitter in female patients.
引文
[1]SATALOFF R T,HAWKSHAW M J,徐文.咽喉反流性疾病[J].中华耳鼻咽喉头颈外科杂志,2014,(5):432-436.
[2]LECHIEN J R,SAUSSEZ S,HARMEGNIES B,et al.Laryngopharyngeal reflux and voice disorders:a multifactorial model of etiology and pathophysiology.[J]Journal of Voice,2017,31(6):733-752.
[3]JACOB P,KAHRILAS P J,HERZON G.Proximal esophageal pH-metry in patients with reflux laryngitis[J].Gastroenterology,1991,100(2):305-310.
[4]中华耳鼻咽喉头颈外科杂志编辑委员会咽喉组,中华医学会耳鼻咽喉头颈外科分会咽喉学组.咽喉反流性疾病诊断与治疗专家共识(2015年)[J].中华耳鼻咽喉头颈外科杂志,2016,51(5):324-326.
[5]斯诺,瓦奇姆,李大庆.Ballenger耳鼻咽喉头颈外科学:喉与支气管食管病学分册[M].北京:人民卫生出版社,2012.
[6]王秀,陈伟,王秋萍.胃蛋白酶检测在咽喉反流疾病诊断中的应用[J].临床耳鼻咽喉头颈外科杂志,2017,31(9):728-731.
[7]陈伟,季寒,吴明海,等.抑酸治疗对声带白斑术后相关症状的影响[J].医学研究生学报,2017,30(1):66-69.
[8]郦振伟,周水洪.咽喉反流和喉癌前病变[J].中华耳鼻咽喉头颈外科杂志,2017,52(8):637-639.
[9]闫燕,万苡辰,刘庆松,等.两种方法诊断咽喉反流患者的嗓音特征及治疗前后变化[J].中国耳鼻咽喉头颈外科,2015,22(9):442-444.
[10]TORREJANO G,GUI MARAES I.Voice quality after supracricoid laryngectomy and total laryngectomy with insertion of voice prosthesis[J].J Voice,2009,23(2):240-246.
[11]时海波,张亮,刘业海.老年反流性咽喉炎的诊断与治疗[J].实用老年医学,2014,28(5):363-367.
[12]JOHNSTON N,BULMER D,GILL G A,et al.Cell biology of laryngeal epithelial defenses in health and disease:further studies[J].Ann Otol Rhinol Laryngol,2003,112(6):481-491.
[13]吴修法,徐洁洁,乔明哲,等.反流性咽喉病患者嗓音声学特征分析[J].听力学及言语疾病杂志,2012,20(3):221-224.
[14]黄永望.实用临床嗓音医学[M].天津:科技翻译出版公司,2012.
[15]DAM R,VMV J,LOPEZ X H,et al.Acoustic analysis of voice and electroglottography in patients with laryngopharyngeal reflux[J].JVoice,2018,32(3):281-284.
[2]LECHIEN J R,SAUSSEZ S,HARMEGNIES B,et al.Laryngopharyngeal reflux and voice disorders:a multifactorial model of etiology and pathophysiology.[J]Journal of Voice,2017,31(6):733-752.
[3]JACOB P,KAHRILAS P J,HERZON G.Proximal esophageal pH-metry in patients with reflux laryngitis[J].Gastroenterology,1991,100(2):305-310.
[4]中华耳鼻咽喉头颈外科杂志编辑委员会咽喉组,中华医学会耳鼻咽喉头颈外科分会咽喉学组.咽喉反流性疾病诊断与治疗专家共识(2015年)[J].中华耳鼻咽喉头颈外科杂志,2016,51(5):324-326.
[5]斯诺,瓦奇姆,李大庆.Ballenger耳鼻咽喉头颈外科学:喉与支气管食管病学分册[M].北京:人民卫生出版社,2012.
[6]王秀,陈伟,王秋萍.胃蛋白酶检测在咽喉反流疾病诊断中的应用[J].临床耳鼻咽喉头颈外科杂志,2017,31(9):728-731.
[7]陈伟,季寒,吴明海,等.抑酸治疗对声带白斑术后相关症状的影响[J].医学研究生学报,2017,30(1):66-69.
[8]郦振伟,周水洪.咽喉反流和喉癌前病变[J].中华耳鼻咽喉头颈外科杂志,2017,52(8):637-639.
[9]闫燕,万苡辰,刘庆松,等.两种方法诊断咽喉反流患者的嗓音特征及治疗前后变化[J].中国耳鼻咽喉头颈外科,2015,22(9):442-444.
[10]TORREJANO G,GUI MARAES I.Voice quality after supracricoid laryngectomy and total laryngectomy with insertion of voice prosthesis[J].J Voice,2009,23(2):240-246.
[11]时海波,张亮,刘业海.老年反流性咽喉炎的诊断与治疗[J].实用老年医学,2014,28(5):363-367.
[12]JOHNSTON N,BULMER D,GILL G A,et al.Cell biology of laryngeal epithelial defenses in health and disease:further studies[J].Ann Otol Rhinol Laryngol,2003,112(6):481-491.
[13]吴修法,徐洁洁,乔明哲,等.反流性咽喉病患者嗓音声学特征分析[J].听力学及言语疾病杂志,2012,20(3):221-224.
[14]黄永望.实用临床嗓音医学[M].天津:科技翻译出版公司,2012.
[15]DAM R,VMV J,LOPEZ X H,et al.Acoustic analysis of voice and electroglottography in patients with laryngopharyngeal reflux[J].JVoice,2018,32(3):281-284.