早期预测急性胰腺炎病情严重程度的研究进展
摘要
<正>急性胰腺炎( acute pancreatitis,AP)是指多种病因引起的胰酶激活从而导致胰腺自身消化的急性炎症性疾病。我国AP主要的发病原因是胆源性疾病~[1],随着经济的快速发展及生活水平的提升,高甘油三脂引起AP逐年上升。根据2012年美国亚特兰大AP分类标准~[2],将AP分为轻症急性胰腺炎(mild acute pancreatitis,MAP)、中重症急性胰腺炎
引文
[1] 中华医学会消化病学分会胰腺疾病学组,《中华胰腺病杂志》编辑委员会,《中华消化杂志》编辑委员会.中国急性胰腺炎诊治指南(2013,上海)[J].中华胰腺病杂志,2013,13(2):73-78
[2] Banks PA,Bollen TL,Dervenis C,et al.Classification of acute pancreatitis-2012:revision of the Atlanta classification and definitions by international consensus[J].Gut,2012,62(1):102-111
[3] Ranson JH,Rifkind KM,Turner JW.Prognostic signs and nonoperative peritoneal lavage in acute pancreatitis[J].Surg Gynecol Obstet,1976,143(2):209-219
[4] Ranson JH.Acute pancreatitis[J].Curr Probl Surg,1979,16(11):1-84
[5] Kiat TTJ,Gunasekaran SK,Junnarkar SP,et al.Are traditional scoring systems for severity stratification of acute pancreatitis sufficient?[J].Ann Hepatobiliary Pancreat Surg,2018,22(2):105-115
[6] Chauhan S,Forsmark CE.The difficulty in predicting outcome in acute pancreatitis[J].Am J Gastroenterol,2010,105(2):443-445
[7] Knaus WA,Zimmerman JE,Wagner DP,et al.APACHE-acute physiology and chronic health evaluation:a physiologically based classification system[J].Crit Care Med,1981,9(8):591-597
[8] Knaus WA,Draper EA,Zimmerman JE,et al.APACHEⅡ:a severity of disease classification system[J].Crit Care Med,1981,9(8):591-597
[9] Park JY,Jeon TJ,Ha TH,et al.Bedside index for severity in acute pancreatitis:comparison with other scoring systems in predicting severity and organ failure[J].Hepatobiliary Pancreat Dis Int,2013,12(6):645-650
[10] Wu BU,Johannes RS,Sun X,et al.The early prediction of mortality in acute pancreatitis:a large population-based study[J].Gut,2008,57(12):1698-1703
[11] Valverde-López F,Matas-Cobos AM,Alegría-Motte C,et al.BISAP,RANSON,lactate and others biomarkers in prediction of severe acute pancreatitis in a European cohort[J].J Gastroenterol Hepatol,2017,32(9):1649-1656
[12] Gao W,Yang HX,Ma CE.The value of BISAP score for predicting mortality and severity in acute pancreatitis:a systematic review and meta-analysis[J].PLoS One,2015,10(6):e0130412
[13] Balthazar EJ,Robinson DL,Megibow AJ.Acute pancreatitis:value of CT in establishing prognosis[J].Radiology,1990,174(2):331-336
[14] Khanna AK,Meher S,Prakash S,et al.Comparison of Ranson,Glasgow,MOSS,SIRS,BISAP,APACHE-II,CTSI Scores,IL-6,CRP,and procalcitonin in predicting severity,organ failure,pancreatic necrosis,and mortality in acute pancreatitis[J].HPB Surg,2013:367581
[15] Staubli SM,Oertli D,Nebiker CA.Laboratory markers predicting severity of acute pancreatitis[J].Crit Rev Clin Lab Sci,2015,52(6):273-283
[16] Mofidi R,Suttie SA,Patil PV,et al.The value of procalcitonin at predicting the severity of acute pancreatitis and development of infected pancreatic necrosis:systematic review[J].Surg,2009,146(1):72-81
[17] Purkayastha S,Chow A,Athanasiou T,et al.Does serum procalcitonin have a role in evaluating the severity of acute pancreatitis?A question revisited[J].World J Surg,2006,30(9):1713-1721
[18] Aoun E,Chen J,Reighard D,et al.Diagnostic accuracy of interleukin-6 and interleukin-8 in predicting severe acute pancreatitis:a meta-analysis[J].Pancreatology,2009,9(6):777-785
[19] Ba?ak F,Hasbah?eci M,?i?ik A,et al.Can C-reactive protein level increase the accuracy of the Ranson score in predicting the severity and prognosis of acute pancreatitis?A prospective cohort study[J].Turk J Gastroenterol,2017,28(3):207-213
[20] üstünda Y,Sar?ta? ü.C-reactive protein levels together with the Ranson Scoring System to differentiate the mild and severe forms of acute pancreatitis[J].Turk J Gastroenterol,2017,28(3):157-158
[21] Vinish DB,Abishek V,Sujatha K,et al.Role of bedside pancreatic scores and C-reactive protein in predicting pancreatic fluid collections and necrosis[J].Indian J Gastroenterol,2017,36(1):43-49
[22] Gomez D,Farid S,Malik HZ,et al.Preoperative neutrophil-to-lymphocyte ratio asa prognostic predictor after curative resection for hepatocellular carcinoma[J].World J Surg,2008,32(8):1757-1762
[23] Luo G,Guo M,Liu Z,et al.Blood neutrophil-lymphocyte ratio predicts survival in patients with advanced pancreatic cancer treated with chemotherapy[J].Ann Surg Oncol,2015,22(2):670-676
[24] Gibson PH,Croal BL,Cuthbertson BH,et al.Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting[J].Am Heart J,2007,154(5):995-1002
[25] Suppiah A,Malde D,Arab T,et al.The prognostic value of the neutrophil-lymphocyte ratio (NLR) in acute pancreatitis:identification of an optimal NLR[J].J Gastrointest Surg,2013,17(4):675-681
[26] Li Y,Zhao Y,Feng L,et al.Comparison of the prognostic values of inflammation markers in patients with acute pancreatitis:a retrospective cohort study[J].BMJ Open,2017,7(3):e013206
[27] Suppiah A,Malde D,Arab T,et al.The prognostic value of the neutrophil-lymphocyte ratio (NLR) in acute pancreatitis:identification of an optimal NLR[J].J Gastrointest Surg,2013,17(4):675-681
[28] Zhang Y,Wu W,Dong L,et al.Neutrophil to lymphocyte ratio predicts persistent organ failure and in-hospital mortality in an Asian Chinese population of acute pancreatitis[J].Medicine (Baltimore),2016,95(37):e4746
[29] Jeon TJ,Park JY.Clinical significance of the neutrophil-lymphocyte ratio as an early predictive marker for adverse outcomes in patients with acute pancreatitis[J].World J Gastroenterol,2017,23(21):3883-3889
[30] Han C,Zeng J,Lin R,et al.The utility of neutrophil to lymphocyte ratio and fluid sequestration as an early predictor of severe acute pancreatitis[J].Sci Rep,2017,7(1):10704
[2] Banks PA,Bollen TL,Dervenis C,et al.Classification of acute pancreatitis-2012:revision of the Atlanta classification and definitions by international consensus[J].Gut,2012,62(1):102-111
[3] Ranson JH,Rifkind KM,Turner JW.Prognostic signs and nonoperative peritoneal lavage in acute pancreatitis[J].Surg Gynecol Obstet,1976,143(2):209-219
[4] Ranson JH.Acute pancreatitis[J].Curr Probl Surg,1979,16(11):1-84
[5] Kiat TTJ,Gunasekaran SK,Junnarkar SP,et al.Are traditional scoring systems for severity stratification of acute pancreatitis sufficient?[J].Ann Hepatobiliary Pancreat Surg,2018,22(2):105-115
[6] Chauhan S,Forsmark CE.The difficulty in predicting outcome in acute pancreatitis[J].Am J Gastroenterol,2010,105(2):443-445
[7] Knaus WA,Zimmerman JE,Wagner DP,et al.APACHE-acute physiology and chronic health evaluation:a physiologically based classification system[J].Crit Care Med,1981,9(8):591-597
[8] Knaus WA,Draper EA,Zimmerman JE,et al.APACHEⅡ:a severity of disease classification system[J].Crit Care Med,1981,9(8):591-597
[9] Park JY,Jeon TJ,Ha TH,et al.Bedside index for severity in acute pancreatitis:comparison with other scoring systems in predicting severity and organ failure[J].Hepatobiliary Pancreat Dis Int,2013,12(6):645-650
[10] Wu BU,Johannes RS,Sun X,et al.The early prediction of mortality in acute pancreatitis:a large population-based study[J].Gut,2008,57(12):1698-1703
[11] Valverde-López F,Matas-Cobos AM,Alegría-Motte C,et al.BISAP,RANSON,lactate and others biomarkers in prediction of severe acute pancreatitis in a European cohort[J].J Gastroenterol Hepatol,2017,32(9):1649-1656
[12] Gao W,Yang HX,Ma CE.The value of BISAP score for predicting mortality and severity in acute pancreatitis:a systematic review and meta-analysis[J].PLoS One,2015,10(6):e0130412
[13] Balthazar EJ,Robinson DL,Megibow AJ.Acute pancreatitis:value of CT in establishing prognosis[J].Radiology,1990,174(2):331-336
[14] Khanna AK,Meher S,Prakash S,et al.Comparison of Ranson,Glasgow,MOSS,SIRS,BISAP,APACHE-II,CTSI Scores,IL-6,CRP,and procalcitonin in predicting severity,organ failure,pancreatic necrosis,and mortality in acute pancreatitis[J].HPB Surg,2013:367581
[15] Staubli SM,Oertli D,Nebiker CA.Laboratory markers predicting severity of acute pancreatitis[J].Crit Rev Clin Lab Sci,2015,52(6):273-283
[16] Mofidi R,Suttie SA,Patil PV,et al.The value of procalcitonin at predicting the severity of acute pancreatitis and development of infected pancreatic necrosis:systematic review[J].Surg,2009,146(1):72-81
[17] Purkayastha S,Chow A,Athanasiou T,et al.Does serum procalcitonin have a role in evaluating the severity of acute pancreatitis?A question revisited[J].World J Surg,2006,30(9):1713-1721
[18] Aoun E,Chen J,Reighard D,et al.Diagnostic accuracy of interleukin-6 and interleukin-8 in predicting severe acute pancreatitis:a meta-analysis[J].Pancreatology,2009,9(6):777-785
[19] Ba?ak F,Hasbah?eci M,?i?ik A,et al.Can C-reactive protein level increase the accuracy of the Ranson score in predicting the severity and prognosis of acute pancreatitis?A prospective cohort study[J].Turk J Gastroenterol,2017,28(3):207-213
[20] üstünda Y,Sar?ta? ü.C-reactive protein levels together with the Ranson Scoring System to differentiate the mild and severe forms of acute pancreatitis[J].Turk J Gastroenterol,2017,28(3):157-158
[21] Vinish DB,Abishek V,Sujatha K,et al.Role of bedside pancreatic scores and C-reactive protein in predicting pancreatic fluid collections and necrosis[J].Indian J Gastroenterol,2017,36(1):43-49
[22] Gomez D,Farid S,Malik HZ,et al.Preoperative neutrophil-to-lymphocyte ratio asa prognostic predictor after curative resection for hepatocellular carcinoma[J].World J Surg,2008,32(8):1757-1762
[23] Luo G,Guo M,Liu Z,et al.Blood neutrophil-lymphocyte ratio predicts survival in patients with advanced pancreatic cancer treated with chemotherapy[J].Ann Surg Oncol,2015,22(2):670-676
[24] Gibson PH,Croal BL,Cuthbertson BH,et al.Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting[J].Am Heart J,2007,154(5):995-1002
[25] Suppiah A,Malde D,Arab T,et al.The prognostic value of the neutrophil-lymphocyte ratio (NLR) in acute pancreatitis:identification of an optimal NLR[J].J Gastrointest Surg,2013,17(4):675-681
[26] Li Y,Zhao Y,Feng L,et al.Comparison of the prognostic values of inflammation markers in patients with acute pancreatitis:a retrospective cohort study[J].BMJ Open,2017,7(3):e013206
[27] Suppiah A,Malde D,Arab T,et al.The prognostic value of the neutrophil-lymphocyte ratio (NLR) in acute pancreatitis:identification of an optimal NLR[J].J Gastrointest Surg,2013,17(4):675-681
[28] Zhang Y,Wu W,Dong L,et al.Neutrophil to lymphocyte ratio predicts persistent organ failure and in-hospital mortality in an Asian Chinese population of acute pancreatitis[J].Medicine (Baltimore),2016,95(37):e4746
[29] Jeon TJ,Park JY.Clinical significance of the neutrophil-lymphocyte ratio as an early predictive marker for adverse outcomes in patients with acute pancreatitis[J].World J Gastroenterol,2017,23(21):3883-3889
[30] Han C,Zeng J,Lin R,et al.The utility of neutrophil to lymphocyte ratio and fluid sequestration as an early predictor of severe acute pancreatitis[J].Sci Rep,2017,7(1):10704