微创手术与开放手术治疗非小细胞肺癌临床效果对比分析
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摘要
目的研究微创手术与开放手术治疗非小细胞肺癌的临床效果。方法选取2016年2月—2017年2月我院收治的90例非小细胞肺癌患者,将其纳入本次研究,利用数字随机表法的原则,将研究的患者分成两组:实验组和参照组,每组45例;参照组采用开放手术进行治疗,实验组采用微创手术进行治疗,对比两组患者的手术指标与治疗效果、并发症情况。结果对比分析两组患者的临床效果,实验组在手术时间、术中出血量、术后置管时间、住院时间方面好于参照组,t值检验,t值依次为2.264 9、3.099 7、5.690 4、5.801 7,P <0.05,实验组并发症发生率(6.67%)低于参照组(22.22%),总有效率(95.56%)高于参照组(82.22%),实验组手术方法更具有优势(P <0.05),差异具有统计学意义。结论传统的开放手术与微创手术均可以治疗非小细胞肺癌患者,但微创手术方法效果更好,可以减少并发症的发生,提高患者的生活质量,与开放手术相比,优势更加明显,具有一定的临床应用价值。
Objective To study the clinical effect of minimally invasive surgery and open surgery in the treatment of non-small cell lung cancer. Methods 90 cases of non-small cell lung cancer patients in our hospital from February 2016 to February 2017 were selected to be included in this study. The patients were divided into two groups: the experimental group and the reference group, 45 cases in each group; The reference group was treated with open surgery, and the experimental group was treated with minimally invasive surgery. The results of the two groups were compared with the results of the treatment and the complications. Results The clinical effects of the two groups were compared and analyzed, the experimental group in the operation time, intraoperative bleeding volume, post operation time, hospital time was better than the reference group, t value test, t values were 2.264 9, 3.099 7, 5.690 4, 5.801 7, P < 0.05, the incidence of complications in the experimental group(6.67%) was lower than the reference group(22.22%), the total effective rate(95.56%) was higher than that of the reference group(82.22%), and the experimental group had more advantages(P < 0.05). Conclusion The traditional open operation and minimally invasive surgery can treat the patients with non-small cell lung cancer, but the minimally invasive surgery method has better effect, can reduce the occurrence of complications and improve the quality of life of the patients. Compared with the open operation, the advantages are more obvious andhave certain clinical value.
Objective To study the clinical effect of minimally invasive surgery and open surgery in the treatment of non-small cell lung cancer. Methods 90 cases of non-small cell lung cancer patients in our hospital from February 2016 to February 2017 were selected to be included in this study. The patients were divided into two groups: the experimental group and the reference group, 45 cases in each group; The reference group was treated with open surgery, and the experimental group was treated with minimally invasive surgery. The results of the two groups were compared with the results of the treatment and the complications. Results The clinical effects of the two groups were compared and analyzed, the experimental group in the operation time, intraoperative bleeding volume, post operation time, hospital time was better than the reference group, t value test, t values were 2.264 9, 3.099 7, 5.690 4, 5.801 7, P < 0.05, the incidence of complications in the experimental group(6.67%) was lower than the reference group(22.22%), the total effective rate(95.56%) was higher than that of the reference group(82.22%), and the experimental group had more advantages(P < 0.05). Conclusion The traditional open operation and minimally invasive surgery can treat the patients with non-small cell lung cancer, but the minimally invasive surgery method has better effect, can reduce the occurrence of complications and improve the quality of life of the patients. Compared with the open operation, the advantages are more obvious andhave certain clinical value.
引文
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[11]杨欣,曾兴建,付娟.全胸腔镜与后外侧开胸手术对非小细胞肺癌患者的早期创伤指标及免疫功能的影响[J].实用临床医药杂志,2016,20(19):86-87,90.
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[13]蔡杰飞,赵维彩,刘娜,等.非小细胞肺癌患者应用胸腔镜肺叶切除术的治疗效果[J].临床肺科杂志,2016,21(10):1785-1787.
[2]王兵,律方,赵亮,等.完全电视胸腔镜手术与胸腔镜辅助小切口手术治疗早期非小细胞肺癌临床疗效的Meta分析[J].中国肺癌杂志,2017,20(5):303-311.
[3]容宇,郝雁冰,陈万生,等.Ⅰ/Ⅱ期非小细胞肺癌患者微创手术的近远期效果研究[J].实用癌症杂志,2015,30(8):1160-1162.
[4]岳东升,王长利.非小细胞肺癌的手术标准及预后分析[J].中华肿瘤杂志,2014,36(7):532-535.
[5]鲍彤,肖飞,刘德若,等.非小细胞肺癌合并左房瘤栓病例的手术治疗与围术期管理[J].中国肺癌杂志,2018,21(1):24-31.
[6]霍彬,霍小东,王磊,等.CT联合模板引导放射性粒子植入治疗不可手术的早期非小细胞肺癌[J].中华放射医学与防护杂志,2017,37(7):500-504.
[7]苗春兴,张霞,李胜龙等.非小细胞肺癌患者微创手术短期和长期效果及相关因素研究[J].中国医药科学,2017,7(6):123-125,128.
[8]陈高阳,张志胜.同步放化疗联合靶向治疗中晚期非小细胞肺癌疗效观察[J].中国肿瘤临床与康复,2017,24(11):1298-1300.
[9]杨泽波.胸腔镜肺癌手术对老年非小细胞肺癌患者心肺功能及血清免疫指标的影响[J].中国老年学杂志,2018,38(1):137-139.
[10]袁冲,褚文炎,吴道立,等.胸腔镜辅助微创手术与传统开胸手术治疗非小细胞肺癌效果比较[J].中国乡村医药,2018,25(8):25-26.
[11]杨欣,曾兴建,付娟.全胸腔镜与后外侧开胸手术对非小细胞肺癌患者的早期创伤指标及免疫功能的影响[J].实用临床医药杂志,2016,20(19):86-87,90.
[12]徐翼,韩云峰,纪沛君,等.胸腔镜胸膜固定术治疗非小细胞肺癌恶性胸腔积液的观察[J].中国继续医学教育,2018,10(28):109-111.
[13]蔡杰飞,赵维彩,刘娜,等.非小细胞肺癌患者应用胸腔镜肺叶切除术的治疗效果[J].临床肺科杂志,2016,21(10):1785-1787.