超声造影辅助经直肠前列腺穿刺在前列腺癌诊断中的临床价值探讨
摘要
目的对比评价超声造影辅助经直肠前列腺穿刺与常规经直肠前列腺穿刺在前列腺癌诊断中的临床价值。方法选取2016年3月至2017年12月本院门诊及病房的可疑前列腺癌患者158例。采用简单随机抽样方法分为两组:造影穿刺组71例,常规穿刺组87例。比较两组间的总体阳性率、单针阳性率及人均平均穿刺针数。结果造影穿刺组总体阳性率为39.4%(28/71),常规穿刺组总体阳性率为27.6%(24/87),组间比较差异有统计学意义(P<0.05)。造影穿刺组单针阳性率为22.3%(127/569),常规穿刺组单针阳性率为12.3%(139/1131),组间比较差异有统计学意义(P<0.05)。造影穿刺组人均穿刺针数8.01针(569/71),常规穿刺组人均穿刺针数13针(1131/87),组间比较差异有统计学意义(P<0.05)。结论在前列腺癌诊断中,超声造影辅助经直肠前列腺穿刺较常规经直肠前列腺穿刺可以提高临床前列腺癌的诊断率,减少穿刺针数,有一定的临床价值。
引文
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[14]Halpern EJ, Gomella LG, Forsberg F, et al.Contrast enhanced transrectal ultrasound for the detection of prostate cancer:a randomized,double-blind trial of dutasteride pretreatment[J].J Urol,2012,188(5):1739-1745.DOI:10.1016/j.juro.2012.07.021.
[2]Acher P,Dooldeniya M.Prostate biopsy:will transperineal replace transrectal?[J].BJU Int, 2013, 112(5):533-534.DOI:10.1111/bju.12299.
[3]Hodge KK, McNeal JE, Terris MK, et al.Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate[J].J Urol, 1989,142(1):71-74; discussion 74-75.
[4]Singh H, canto El, Shariat SF, et al.Improved detection of clinically significant, curable prostate cancer with systematic 12-core biosy[J].J Urol,2004, 171:1089-1092.DOI:10.1097/01.ju.0000112763.74119.d4.
[5]Paul R, Sch?ler S, van Randenborgh H, et al.Morbidity of prostatic biopsy for different biopsy strategies:is there a relation to core number and sampling region?[J].Eur Urol,2004,45(4):450-455:discussion 456.
[6]Halpern EJ, Strup SE.Using gray-scale and color and power Doppler sonography to detect prostatic cancer[J].AJR Am J Roentgenol,2000,174(3):623-627.
[7]Kabakci N, Igci E, Secil M, et al.Echo contrast-enhanced power Doppler ultrasonography for assessment of angiogenesis in renal cell carcinoma[J].J Ultrasound Med, 2005,24(6):747-753.
[8]Nicolau C, BrúC.Focal liver lesions:evaluation with contrast-enhanced ultrasonography[J].Abdom Imaging, 2004,29(3):348-359.
[9]李小鹏,何鑫,姜钰,等.经直肠超声造影在前列腺癌诊断中的应用[J].现代泌尿外科杂志,2015,20(3):156-158.DOI:10.3969/j.issn.1009-8291.2015-03-005.
[10]李慎义,陈莉.经直肠超声造影鉴别诊断弥漫性前列腺癌[J].中国医学影像技术,2012,28(3):562-565.
[11]Fillon M.Contrast-enhanced ultrasound may aid prostate cancer detection[J].J Natl Cancer Inst, 2013,105(7):444-446.DOI:10.1093/jnci/djt079.
[12]Heijmink SW, Barentsz JO.Contrast-enhanced versus systematic transrectal ultrasound-guided prostate cancer detection:an overview of techniques and a systematic review[J].Eur J Radiol,2007,63(3):310-316.
[13]邵剑锋,徐卓群,胡强,等.超声造影检查在经会阴前列腺穿刺活检中的应用价值[J].中华泌尿外科杂志,2010,31(6):399-401.DOI:10.3760/cma.j.issn.1000-6702.2010.06.013.
[14]Halpern EJ, Gomella LG, Forsberg F, et al.Contrast enhanced transrectal ultrasound for the detection of prostate cancer:a randomized,double-blind trial of dutasteride pretreatment[J].J Urol,2012,188(5):1739-1745.DOI:10.1016/j.juro.2012.07.021.