一效散在晚期恶性肿瘤并发压疮患者治疗中的疗效评价研究
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摘要
目的研究一效散在晚期恶性肿瘤并发压疮患者中的临床疗效。方法选择我院收治的并发压疮的晚期恶性肿瘤患者90例,应用随机数字表法分为对照组和观察组,各45例。对照组采取常规治疗及常规护理手段,观察组在对照组基础上应用一效散外敷配合治疗。观察两组患者的压疮面积、压疮愈合时间、压疮创面愈合疗效、疮面结痂率、疼痛情况、压疮愈合评分、换药频次、药物费用。结果治疗后,观察组患者的压疮面积、压疮愈合时间、压疮创面愈合疗效、疮面结痂率、压疮愈合评分、疼痛评分、换药频次、药物费用方面均优于对照组,差异有统计学意义(P<0.05)。结论晚期恶性肿瘤并发压疮患者配合应用一效散,可有效促进压疮的愈合,降低换药频次,提高愈合疗效,减少治疗费用。
Objective To study the clinical efficacy of Yixiao Powder in the treatment of advanced malignant tumors complicated with pressure ulcers. Methods Ninety patients with advanced tumors complicated with pressure ulcers in our hospital were divided into control group and observation group by random number table method, 45 cases in each group. The control group was treated by routine treatment and routine nursing. The observation group was treated with Yixiao Powder external application on the basis of control group. The area of pressure ulcer, the healing time, healing effect of pressure ulcer wound, scab rate, pain scores, healing scores of pressure ulcer, dressing change frequency and drug cost were observed and compared between the two groups. Results After treatment, the observation group had better results in all aspects like pressure ulcer area, healing time, healing effect of pressure sore wound, scab rate, healing scores, pain scores, frequency of dressing change and drug cost than the control group, and the differences were all statistically significant(P<0.05).Conclusion The combined use of Yixiao Powder can effectively improve the healing of pressure sores in patients with advanced malignant tumors, reduce the frequency of dressing change, improve the healing effect and reduce the cost of treatment.
Objective To study the clinical efficacy of Yixiao Powder in the treatment of advanced malignant tumors complicated with pressure ulcers. Methods Ninety patients with advanced tumors complicated with pressure ulcers in our hospital were divided into control group and observation group by random number table method, 45 cases in each group. The control group was treated by routine treatment and routine nursing. The observation group was treated with Yixiao Powder external application on the basis of control group. The area of pressure ulcer, the healing time, healing effect of pressure ulcer wound, scab rate, pain scores, healing scores of pressure ulcer, dressing change frequency and drug cost were observed and compared between the two groups. Results After treatment, the observation group had better results in all aspects like pressure ulcer area, healing time, healing effect of pressure sore wound, scab rate, healing scores, pain scores, frequency of dressing change and drug cost than the control group, and the differences were all statistically significant(P<0.05).Conclusion The combined use of Yixiao Powder can effectively improve the healing of pressure sores in patients with advanced malignant tumors, reduce the frequency of dressing change, improve the healing effect and reduce the cost of treatment.
引文
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[18]朱爱萍,刘虹梅.托里透脓汤与冰片加诺氟沙星联合治疗Ⅲ期、Ⅳ期压疮的临床效果及对其血清TNF-α、IL-6水平的影响[J].四川中医, 2018, 36(4):75-78.
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[21]郭倩.一效散结合3M液体敷料治疗臀裂处压疮临床疗效与护理体会[J].辽宁中医药大学学报, 2019, 21(9):203-205. doi:10.13194/j. issn.1673-842x.2019.01.056.
[22]王喆.一效膏联合抗生素治疗褥疮临床观察[J].辽宁中医药大学学报, 2010, 12(3):134-135. doi:10.13194/j.jlunivtcm.2010.03.136. wangzh.084.
[2]Cushing CA, Phillips LG. Evidence-based medicine:pressure sores[J]. Plast Reconstr Surg, 2013, 132(6):1720-1732. doi:10.1097/PRS.0b013e3182a808ba.
[3]蒋琪霞,李国宏,刘海英,等.减压床垫结合不同翻身频率用于重症患者预防压疮的多中心对照研究[J].医学研究生学报, 2017, 30(1):77-82. doi:10.16571/j. cnki.1008-8199.2017.01.016.
[4]蒋琪霞,刘洁.64例医院内获得性压疮的原因分析及对策[J].中华现代护理杂志, 2014, 20(11):1244-1247. doi:10.3760/j. issn.1674-2907.2014.11.002.
[5]Morisky DE, Ang A, Krousel-Wood M, et al. Predictive validity of a medication adherence measure in an outpatient setting[J]. J Clin Hypertens(Greenwich), 2008, 10(5):348-354.
[6]柴政.一效膏促进慢性皮肤溃疡创面修复的研究[D].沈阳:辽宁中医药大学, 2016.
[7]刘学夫,李忠卓.一效散及膏的药物解析和在肛肠科的运用[J].中医药临床, 2016, 28(11):1570-1572. doi:10.16448/j. cjtcm.2016.0553.
[8]管晓萍.压疮分期判断标准(2007年NPUAP)[C].中华护理学会全国肿瘤护理新进展研讨会, 2007.
[9]张杰,武春娟,王飞,等.晚期肿瘤压疮患者采用水胶体敷料治疗临床价值分析[J].河北医药, 2017, 39(24):3827-3829, 3832. doi:10.3969/j. issn.1002-7386.2017.24.046.
[10]白龙,殷东风,李鹰.一效散及膏外敷治疗晚期肿瘤并发褥疮的疗效观察[J].现代中西医结合杂志, 2009,18(13):1456-1457. doi:10.3969/j. issn.1008-8849.2009.13.004.
[11]李淑梅,谢小兰,王珍.艾灸联合生红液治疗Ⅲ期压疮的疗效观察与护理[J].中国临床护理, 2018, 10(3):210-215. doi:10.3969/j. issn.1674-3768.2018.03.008.
[12]吴乾.橡皮生肌膏辅助治疗晚期肿瘤合并褥疮的疗效观察[J].山西医药杂志, 2006, 35(9):825. doi:10.3969/j.issn.0253-9926.2006.09.033.
[13]李海棠,邓正定,陆红珍.自制中药枕联合耳穴埋豆对维持性血液透析患者睡眠障碍的影响[J].齐鲁护理杂志, 2018, 24(23):67-70. doi:v.
[14]黄珍珠,冯莹,熊婷.热敏灸配合中药外敷用于压疮护理的效果观察[J].医学理论与实践, 2017, 30(2):3566-3568. doi:10.19381/j. issn.1001-7585.2017.23.067.
[15]谢海燕.艾灸联合龙血竭治疗压疮30例护理体会[J].云南中医中药杂志, 2017, 38(11):91-93. doi:10.3969/j.issn.1007-2349.2017.11.039.
[16]DemarréL, Verhaeghe S, Van Hecke A, et al. The effectiveness of three types of alternating pressure air mattresses in the prevention of pressure ulcers in Belgian hospitals[J]. Res Nurs Health, 2013, 36(5):439-452. doi:10.1002/nur.21557.
[17]王静,于永铎.生肌止痛栓联合一效膏用于混合痔术后的临床观察[J].中医外治杂志, 2016, 25(6)16-17. doi:10.3969/j. issn.1006-978X.2016.06.007.
[18]朱爱萍,刘虹梅.托里透脓汤与冰片加诺氟沙星联合治疗Ⅲ期、Ⅳ期压疮的临床效果及对其血清TNF-α、IL-6水平的影响[J].四川中医, 2018, 36(4):75-78.
[19]张少乾.中蒙医药朱砂应用的配伍规律研究[D].北京:北京中医药大学, 2018.
[20]秦鹤.一效膏外敷联合中药熏洗治疗湿热下注型混合痔术后疗效观察[D].沈阳:辽宁中医药大学, 2017.
[21]郭倩.一效散结合3M液体敷料治疗臀裂处压疮临床疗效与护理体会[J].辽宁中医药大学学报, 2019, 21(9):203-205. doi:10.13194/j. issn.1673-842x.2019.01.056.
[22]王喆.一效膏联合抗生素治疗褥疮临床观察[J].辽宁中医药大学学报, 2010, 12(3):134-135. doi:10.13194/j.jlunivtcm.2010.03.136. wangzh.084.