摘要
目的探讨肥胖高血压患者血浆内皮素-1(ET-1)与房颤发生率的关系。方法选取高血压患者150例,以BMI作为依据分为三组,超重组即BMI≥24合并高血压60例,正常组即18.5
引文
[1] 黄从新,张澍,马长生,等.心房颤动:目前的认识和治疗建议[J].中华心律失常学杂志,2012,14(4):328-369.
[2] Elliott AD,Mahajan R,Lau DH,et al.Atrial fibrillation in endurance athletes:from mechanism to management[J].Cardiol Clin,2016,34(4):567-578.
[3] Akoum N.New perspectives on atrial fibrillation and stroke[J].Heart,2016,24:309066.
[4] Ferrari R,Bertini M,Blomstrom-Lundqvist C,et al.An update on atrial fibrillation in 2014:from pathophysiology to treatment[J].Int J Cardiol,2016,15(203):22-29.
[5] Barton M.Obesity and aging:determinants of endothelial cell dysfunction and atherosclerosis[J].Pflugers Arch,2010,460(5):825-837.
[6] 尹新华,章丽丽.超重或肥胖对高血压患者血管内皮功能的影响[J].实用临床医学,2012,13(3):14-16.
[7] Lau DH,Middeldorp ME,Sanders P.Obesity paradox in atrial fibrillation:a distracting reality or fictitious finding?[J].Eur Heart J,2016 ,17:261.
[8] Gras E,Belaidi E,Briancon-Marjollet A,et al.Endothelin-1 mediates intermittent hypoxia-induced inflammatory vascular remodeling through HIF-1 activation[J].J Appl Physiol(1985),2016,120(4):437-443.
[9] Zakeri R,Borlaug BA,McNulty SE,et al.Impact of atrial fibrillation on exercise capacity in heart failure with preserved ejection fraction:a relax trial ancillary study[J].Circ Heart Fail,2014,7:123-130.
[10] Abed HS,Samuel CS,Lau DH,et al.Obesity results in progressive atrial structural and electrical remodeling:implications for atrial fibrillation[J].Heart Rhythm,2013,10:90-100.