摘要
<正>儿童慢性肾脏疾病(CKD)起病隐匿不易发现,某些无症状儿童可能有血尿和(或)蛋白尿,如不能及早发现,部分患者可转化为慢性肾功能不全,严重影响患儿身心健康,也增加家庭及社会的负担。因此,在健康儿童中开展尿常规及肾脏B超等筛查,及时发现各种未出现症状的泌尿系统疾病,提供早期干预的时机并及时治疗是十分重要的。本文主要介绍尿常规筛查的作用。
引文
[1]LEVEY A S,ECKARDT K U,TSUKAMOTO Y,et al.Definition and classification of chronic kidney disease:a position statement from Kidney Disease:Improving Global Outcomes(KDIGO)[J].Kidney Int,2005,67(6):2089-2100.
[2]VIANELLO F A,MAZZONI M B,PEETERS G G,et al.Micro and macro-scopic hematuria caused by renal vein entrapment:systematic re-view of the literatur[J].Pediatric Nephrology,2016,31(2):175-184.
[3]YAP H K,QUEK C M,SHEN Q,et al.Role of urinary screening programmes in children in the prevention of chronic kidney disease[J].Ann Acad Med Singapore,2005,34(1):1-7.
[4]徐虹.儿童肾脏病早期发现的策略探讨[J].中国实用儿科杂志,2018,33(2):89-92.
[5]缪千帆,沈茜,徐虹,等.慢性肾脏病2~5期患儿264例病因构成分析[J].中华儿科杂志,2015,53(9):665-669.
[6]PARK Y H,CHOI J Y,CHUNG H S,et al.Hematuria and proteinuria in a mass school urine screening test[J].Pediatr Nephrol,2005,20(8):1126-1130.
[7]YAMAGATA K,ISEKI K,NITTA K,et a1.chronic kidney disease perspectives in Japan and the importance of urinalysis screening[J].Clin Exp Nephrol,2008,12(1):1-8.
[8]CHO B S,HAHN W H,CHEONG H I,et al.A nationwide study of mass urine screening tests on Korean school children and implications for chronic kidney disease management[J].Clin Exp Nephrol,2013,17(2):205-210.
[9]ALHARTHI A A,TAHA A A,EDREES A E,et al.Screening for urine ab-normalities among preschool children in western Saudi Arabia[J].Saudi Med J,2015,35(12):371-372.
[10]HARAMBAT J,VAN STRALEN K J,KIM J J,et al.Epidemiology of chronic kidney disease in children[J].Pediatr Nephrol,2012,27(3):363-373.
[11]MOGHTADERI M,NOOHI A H,SAFAEYAN B,et al.Screening for mi-croscopic hematuria in school-age children of gorgan city[J].Iran J Kidney Dis,2014,8(1):70-72.
[12]OKUR M,ARSLAN S,SAMI G A,et al.Determination of underlying causes in asymptomatic,early-stage renal diseases by dipstick test[J].Med Glas(Zenica),2013,10(1):55-58.
[13]全国儿科肾脏病学组.儿童泌尿系统疾病流行病学调查:全国21省市尿筛查小结[J].中华儿科杂志,1988,27(2):304-306.
[14]沈彤,彭桂兰,张慧芬,等.厦门市34 455名儿童尿常规筛查分析[J].中国儿童保健杂志,2009,17(1):89-91.
[15]WU D,YANG H,LUO J,et al.Age-and gender-specific reference values for urine albumin/creatinine ratio in children of southwest China[J].Clinica Chimica Acta,2014,431:239-243.
[16]高霞,刘姝娆,雷晓燕,等.甘肃省某贫困地区3662例儿童尿常规筛查结果分析[J].山东医药,2017,57(46):20-23.
[17]杨平,陈晓云,张明.2011-2013年泰安市中小学生尿液筛查结果分析[J].中国妇幼保健,2015,30(21):3602-3604.
[18]HATTORI M,SAKO M,KANEKO T,et al.End-stage renal disease in Japanese children:a nationwide survey during 2006-2011[J].Clin Exp Nephrol,2015,19(5):933-938.
[19]YAMAGATA K,TAKAHASHI H,SUZUKI S,et al.Age distribution and yearly changes in the incidence of ESRD in Japan[J].Am J Kidney Dis,2004,43(3):433-443.
[20]NATIONAL KIDNEY FUNDATION.K/DOQI clinical practice guidelines for chronic kidney disease:evaluation,classification and stratification.Part 4.Definition and classification of stages of chronic kidney diseases[J].Am J Kidney Dis,2002,39(2Suppl 1):S46-S75.