电针天枢、腹结穴对功能性便秘患者排便次数和生活质量的影响及疗效评价
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摘要
目的:观察电针天枢、腹结穴对功能性便秘患者自主排便次数及生活质量的影响及疗效评价。方法:将纳入研究的120例功能性便秘患者,随机分为治疗组(电针组)和对照组(假电针组)。电针组取天枢、腹结穴,假电针组选取双侧天枢旁、腹结旁,两组每周均治疗3次,治疗周期均为4周,随访4周,取周完全自主排便次数(CSBMs)为主要观察指标,便秘患者生活质量量表(PAC-QOL)为次要观察指标,分别于治疗4周和随访4周进行疗效评价。同时我们还观察两组的不良反应。结果:治疗4周和随访4周,两种方法与基线相比均能增加患者CSBMs、改善患者PAC-QOL评分(P<0.05),但电针组疗效明显优于假电针组,差异具有统计学意义(P<0.05)。两组患者安全性无差别。结论:电针天枢、腹结可以有效提高功能性便秘患者自主排便次数,同时提高患者的生活质量,疗效确切,值得在临床中推广应用。
Objective:To observe the effect of electroacupuncture(EA) at Tianshu(ST 25),Fujie(SP 14) on spontaneous bowel movements and life quality of function constipation. Methods:One hundred and twenty functional constipation patients were randomly divided into a treatment group(EA group) and a controlled group(sham-EA group),and each group had 60 cases. Patients in the treatment group were treated with EA at bilateral Tianshu(ST 25),Fujie(SP 14),and those in the sham-EA group were received superficial acupuncture at 1 Cun lateral to the identical acupoints without electrical current delivery. The treatment was given 3 times a week. The period of research was 8 weeks,including 4 weeks for treatment and 4 weeks for follow-up. The weekly complete spontaneous bowel movements(CSBMs) was taken as primary index,while the quality of life of patients with constipation(PAC-QOL) score was taken as the secondary indices for the efficacy evaluation after treatment. Safety was also assessed. Results:The spontaneous bowel movements and life of patients with constipation(PAC-QOL) score of the two groups were both improved(P<0.05). The improvement of the EA group was more statistically significant(P<0.05). After receiving treatment for 4 weeks and 4 weeks for follow-up,the improvement of the PAC-QOL scores of the EA group was significant(P<0.05). Conclusion:Electroacupuncturing at Tianshu(ST 25),Fujie(SP 14) treatment can improve the complete spontaneous bowel movements and life quality of patient with function constipation. The curative effect is definite and it is worthy of clinical practice.
Objective:To observe the effect of electroacupuncture(EA) at Tianshu(ST 25),Fujie(SP 14) on spontaneous bowel movements and life quality of function constipation. Methods:One hundred and twenty functional constipation patients were randomly divided into a treatment group(EA group) and a controlled group(sham-EA group),and each group had 60 cases. Patients in the treatment group were treated with EA at bilateral Tianshu(ST 25),Fujie(SP 14),and those in the sham-EA group were received superficial acupuncture at 1 Cun lateral to the identical acupoints without electrical current delivery. The treatment was given 3 times a week. The period of research was 8 weeks,including 4 weeks for treatment and 4 weeks for follow-up. The weekly complete spontaneous bowel movements(CSBMs) was taken as primary index,while the quality of life of patients with constipation(PAC-QOL) score was taken as the secondary indices for the efficacy evaluation after treatment. Safety was also assessed. Results:The spontaneous bowel movements and life of patients with constipation(PAC-QOL) score of the two groups were both improved(P<0.05). The improvement of the EA group was more statistically significant(P<0.05). After receiving treatment for 4 weeks and 4 weeks for follow-up,the improvement of the PAC-QOL scores of the EA group was significant(P<0.05). Conclusion:Electroacupuncturing at Tianshu(ST 25),Fujie(SP 14) treatment can improve the complete spontaneous bowel movements and life quality of patient with function constipation. The curative effect is definite and it is worthy of clinical practice.
引文
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[11] 赵贞贞,林征,林琳,等.中文版患者便秘状况评估量表在应用评价中的信效度研究[J].中华护理杂志,2010,45(12):1124～1126
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[2] 王成伟,李宁,何洪波,等.电针双侧天枢穴对功能性便秘患者自觉症状的影响及疗效满意度评价:一项单中心,前瞻性随机对照临床试验[J].针刺研究,2010,35(5):375～379
[3] 陈璐,孙建华,吴晓亮,等.电针深刺对女性严重功能性便秘患者自主排便次数及生活质量的影响[J].南京中医药大学学报,2016,32(1):10～13
[4] Xue QM,Li N,Liu ZS,et al.Efficacy of Electroacupuncture in the Treatment of Functional Constipation:A Randomized Controlled Pilot Trial[J].Chin J Integr Med,2015,21(6):459～463
[5] Drossman DA,Dumitrascu DL.Rome Ⅲ:new standard for functional gastrointestinal disorders.J Gastrointestin Liver Dis,2006,15(3):237～241
[6] Marquis P,De La Loge C,Dubois D,McDermott A,Chassany O.Development and validation of the Patient Assessment of Constipation Quality of Life questionnaire.Scand J Gastroenterol.2005;40(5):540～551
[7] 张选平,贾春生,王建岭,等.电针疗法的优势病种及应用规律[J].中国针灸,2012,32(10):947～951
[8] Lembo A,Camilleri M.Chronic constipation.N Engl J Med,2003,349(11):1360～1368
[9] Camilleri M,Kerstens R,Rykx A,Vandeplassche L.A placebo-controlled trial of prucalopride for severe chronic constipation.N Engl J Med,2008,358(29):2344～2354
[10] 陈璐,孙建华,吴晓亮,等.电针深刺对女性严重功能性便秘患者自主排便次数及生活质量的影响[J].南京中医药大学学报,2016,32(1):10～13
[11] 赵贞贞,林征,林琳,等.中文版患者便秘状况评估量表在应用评价中的信效度研究[J].中华护理杂志,2010,45(12):1124～1126
[12] 阮慧红,黄志勇,李少霞,等.电针对功能性便秘疗效和生活质量的研究[J].针灸临床杂志,2015,31(2):34～36