白疕合剂治疗血热证寻常型银屑病临床观察
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摘要
目的:观察白疕合剂治疗血热证寻常型银屑病的临床疗效。方法:将患者随机分成治疗组39例、对照组34例。治疗组予口服白疕合剂,对照组予口服复方青黛丸,两组均予口服复方甘草酸苷片,治疗6周后,比较疗效。结果:两组治疗后PASI均低于治疗前(P<0.01),两组比较无明显差异(P>0.05);两组有效率比较(治疗组74.36%、对照组61.76%),差异无统计学意义(P>0.05)。结论:白疕合剂与复方青黛丸治疗血热证寻常型银屑病效果好,无明显不良反应,值得推广。
Objective: To observe the White Mange Mixture treatment the curative effect of blood heat syndrome with psoriasis vulgaris.Methods: The patients were randomly divided into 39 cases in the treatment group and 34 cases in the control group. Gives oral White Mange Mixture treatment group,control group with oral compound indigo naturalis pills,two groups to give oral compound glycyrrhizin glucoside piece,6 weeks after treatment,the treatment efficacy of two groups patients. Results: After treatment,PASI was lower in both groups than before treatment(P<0.01),and there was no significant difference between the two groups(P>0.05). Effective rate(74.36%in the treatment group and 61.76% in the control group)was not statistically significant(P>0.05). Conclusion: White Mange Mixture with compound indigo naturalis pills have no obvious differences in treatment effect,but the White Mange Mixture has no obvious adverse reactions,and has good curative effect,worthy of promotion and using for reference.
Objective: To observe the White Mange Mixture treatment the curative effect of blood heat syndrome with psoriasis vulgaris.Methods: The patients were randomly divided into 39 cases in the treatment group and 34 cases in the control group. Gives oral White Mange Mixture treatment group,control group with oral compound indigo naturalis pills,two groups to give oral compound glycyrrhizin glucoside piece,6 weeks after treatment,the treatment efficacy of two groups patients. Results: After treatment,PASI was lower in both groups than before treatment(P<0.01),and there was no significant difference between the two groups(P>0.05). Effective rate(74.36%in the treatment group and 61.76% in the control group)was not statistically significant(P>0.05). Conclusion: White Mange Mixture with compound indigo naturalis pills have no obvious differences in treatment effect,but the White Mange Mixture has no obvious adverse reactions,and has good curative effect,worthy of promotion and using for reference.
引文
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[8]王一铮,郑英杰,刘飞飞.复方甘草酸苷的皮肤科临床应用探讨[J].临床医药文献电子杂志,2018,5(13):170.
[9]黄琪,周飞红,李东升.中医治则组方治疗银屑病作用机制的研究进展[J].中国麻风皮肤病杂志,2007,23(6):504-506.
[10]陈兴,卢益萍,李忻红.中药白疕合剂对体外培养HaCaT细胞增殖与凋亡的影响[J].中华中医药学刊,2015,33(12):2961-2963.
[11]陈兴,卢益萍,李忻红.中药白疕合剂对体外培养HaCaT细胞肿瘤坏死因子-α、白细胞介素-6表达的影响[J].中国中西医结合皮肤性病学杂志,2015,14(3):151-153+158.
[12]陈洪艳.中药白疕合剂治疗银屑病作用机制实验研究[D].沈阳:辽宁中医药大学,2013.
[2]李曰庆.中医外科学[M].北京:中国中医药出版社,2007:183-186.
[3]Marks R,Barton SP,Shuttleworth D,et al.Assessment of disease progress in psoriasis[J].Arch Dermatol,1989,125:235-240.
[4]李莉,刘秀琴.中药致药物性肝损伤临床分析[J].实用中医药杂志,2016,32(10):1028-1029.
[5]国家食品药品监督管理总局提醒关注复方青黛丸(胶囊、片)用药风险[J].中国药房,2013,24(20):1867.
[6]包英.复方青黛丸致便血1例[J].工企医刊,2004(6):62.
[7]沈跃莉,叶俊儒.阿维A胶囊联合复方甘草酸苷片对寻常型银屑病患者症状的改善及安全性[J].医学综述,2016,22(17):3491-3493.
[8]王一铮,郑英杰,刘飞飞.复方甘草酸苷的皮肤科临床应用探讨[J].临床医药文献电子杂志,2018,5(13):170.
[9]黄琪,周飞红,李东升.中医治则组方治疗银屑病作用机制的研究进展[J].中国麻风皮肤病杂志,2007,23(6):504-506.
[10]陈兴,卢益萍,李忻红.中药白疕合剂对体外培养HaCaT细胞增殖与凋亡的影响[J].中华中医药学刊,2015,33(12):2961-2963.
[11]陈兴,卢益萍,李忻红.中药白疕合剂对体外培养HaCaT细胞肿瘤坏死因子-α、白细胞介素-6表达的影响[J].中国中西医结合皮肤性病学杂志,2015,14(3):151-153+158.
[12]陈洪艳.中药白疕合剂治疗银屑病作用机制实验研究[D].沈阳:辽宁中医药大学,2013.