幽门螺杆菌根除治疗对特发性血小板减少性紫癜患者血小板计数的影响
摘要
<正>幽门螺杆菌(Hp)是胃炎、消化性溃疡和胃腺癌致病因素。除了胃部疾病,Hp也与各种非胃肠相关疾病,如冠状动脉动脉疾病、自身免疫病和恶性贫血有关~([1])。最近有研究证实,Hp是特发性血小板减少性紫癜(ITP)的致病因素。目前主要采取类固醇、球蛋白、抗RhD、脾切除术、免疫抑制剂和其他疗法用于治疗ITP。在这些治疗方法中,类固醇治疗是最有效的;然而,如果停药,大多数患者可能复发。当使用其他治疗方法时,64%ITP患者表现出
引文
[1]涂莎,阳惠湘.幽门螺杆菌感染治疗的进展[J].中南大学学报(医学版),2014,39(9):981-988.
[2] Sato R,Murakami K,Watanabe K,et al. Development of corpus atrophic gastritis may be associated with Helicobacter pylorirelated idiopathic thrombocytopenic purpura[J]. J Gastroenterol,2011,46(8):991-997.
[3] Kohda K,Kuga T,Kogawa K,et al. Effect of Helicobacter pylori eradication on platelet recovery in Japanese patients with chronic idiopathic thrombocytopenic purpura and secondary autoimmune thrombocytopenic purpura[J]. Br J Haematol,2015,118(2):584-588.
[4] Sato R,Murakami K,Watanabe K,et al. Development of corpus atrophic gastritis may be associated with Helicobacter pylorirelated idiopathic thrombocytopenic purpura[J]. J Gastroenterol,2011,46(8):991-997.
[5] Arnold DM,Bernotas A,Nazi I,et al. Platelet count response to H. pylori treatment in patients with immune thrombocytopenic purpura with and without H. pylori infection:a systematic review[J]. Haematologica,2009,94(6):850-856.
[6]田艳琼.根除幽门螺杆菌对成人特发性血小板减少性紫癜患者疗效的影响[J].中国当代医药,2012,19(5):50-51.
[7] Fujimura K,Kuwana M,Kurata Y,et al. Is eradication therapy useful as the first line of treatment in helicobacter pylori-positive idiopathic thrombocytopenic purpura? Analysis of 207eradicated chronic ITP cases in Japan[J]. Int J Hematology,2005,81(2):162-168.
[2] Sato R,Murakami K,Watanabe K,et al. Development of corpus atrophic gastritis may be associated with Helicobacter pylorirelated idiopathic thrombocytopenic purpura[J]. J Gastroenterol,2011,46(8):991-997.
[3] Kohda K,Kuga T,Kogawa K,et al. Effect of Helicobacter pylori eradication on platelet recovery in Japanese patients with chronic idiopathic thrombocytopenic purpura and secondary autoimmune thrombocytopenic purpura[J]. Br J Haematol,2015,118(2):584-588.
[4] Sato R,Murakami K,Watanabe K,et al. Development of corpus atrophic gastritis may be associated with Helicobacter pylorirelated idiopathic thrombocytopenic purpura[J]. J Gastroenterol,2011,46(8):991-997.
[5] Arnold DM,Bernotas A,Nazi I,et al. Platelet count response to H. pylori treatment in patients with immune thrombocytopenic purpura with and without H. pylori infection:a systematic review[J]. Haematologica,2009,94(6):850-856.
[6]田艳琼.根除幽门螺杆菌对成人特发性血小板减少性紫癜患者疗效的影响[J].中国当代医药,2012,19(5):50-51.
[7] Fujimura K,Kuwana M,Kurata Y,et al. Is eradication therapy useful as the first line of treatment in helicobacter pylori-positive idiopathic thrombocytopenic purpura? Analysis of 207eradicated chronic ITP cases in Japan[J]. Int J Hematology,2005,81(2):162-168.