蛋白质翻译机制的精准性概述
摘要
蛋白质是细胞和生物体功能的重要执行者,若蛋白质的翻译过程出现差错就会造成灾难性的后果。生物机体的众多机制保障了翻译过程的精确无误,本文概述蛋白质翻译机制的精准性。
引文
[1] 卢向阳.分子生物学(第二版)[M].北京:中国农业出版社,2012:200-202.
[2] 严锦文,姜嘉娴.翻译的精确性和准确性[J].生物学通报,1992(5):12-13.
[3] KIMURA S,SUZUKI T.Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA [J].Nucleic Acids Research,2010,38(4):1341-1352.
[4] GRIGORIADOU C,MARZI S,PAN D,et al.The translational fidelity function of if3 during transition from the 30s initiation complex to the 70s initiation complex [J].Journal of Molecular Biology,2007,373(3):551-561.
[5] QIN D,FREDRICK K.Control of translation initiation involves a factor-induced rearrangement of helix 44 of 16S ribosomal RNA [J].Molecular Microbiology,2009,71(5):1239-1249.
[6] ZORZET A,PAVLOV M Y,NILSSON A,et al.Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance [J].Molecular Microbiology,2010,75(5):1299-1313.
[7] 袁红雨.现代分子生物学[M].北京:化学工业出版社,2012:163.
[8] 郭雷,胡洪,任列娇,等.蛋白质翻译起始因子的作用与调控[J].云南农业大学学报:自然科学版,2011(4):554-559.
[9] SONENBERG N,HINNEBUSCH AG.Regulation of translation initiation in eukaryotes:mechanisms and biological targets [J].Cell,2009,136(4):731-745.
[10] NANDA JS,CHEUNG YN,TAKACS JE,et al.eIF1 Controls multiple steps in start codon recognition during eukaryotic translation initiation [J].Journal of Molecular Biology,2009,394(2):268-285.
[11] EFFRAIM PR,WANG J,ENGLANDER MT,et al.Natural amino acids do not require their native tRNAs for efficient selection by the ribosome [J].Nature Chemical Biology,2009,5(12):947-953.
[12] DALE T,FAHLMAN RP,OLEJNICZAK M,et al.Specificity of the ribosomal A site for aminoacyl-tRNAs [J].Nucleic Acids Research,2009,37(4):1202-1210.
[13] ZAHER HS,GREEN R.Quality control by the ribosome following peptide bond formation [J].Nature,2009,457(7226):161-166.
[2] 严锦文,姜嘉娴.翻译的精确性和准确性[J].生物学通报,1992(5):12-13.
[3] KIMURA S,SUZUKI T.Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA [J].Nucleic Acids Research,2010,38(4):1341-1352.
[4] GRIGORIADOU C,MARZI S,PAN D,et al.The translational fidelity function of if3 during transition from the 30s initiation complex to the 70s initiation complex [J].Journal of Molecular Biology,2007,373(3):551-561.
[5] QIN D,FREDRICK K.Control of translation initiation involves a factor-induced rearrangement of helix 44 of 16S ribosomal RNA [J].Molecular Microbiology,2009,71(5):1239-1249.
[6] ZORZET A,PAVLOV M Y,NILSSON A,et al.Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance [J].Molecular Microbiology,2010,75(5):1299-1313.
[7] 袁红雨.现代分子生物学[M].北京:化学工业出版社,2012:163.
[8] 郭雷,胡洪,任列娇,等.蛋白质翻译起始因子的作用与调控[J].云南农业大学学报:自然科学版,2011(4):554-559.
[9] SONENBERG N,HINNEBUSCH AG.Regulation of translation initiation in eukaryotes:mechanisms and biological targets [J].Cell,2009,136(4):731-745.
[10] NANDA JS,CHEUNG YN,TAKACS JE,et al.eIF1 Controls multiple steps in start codon recognition during eukaryotic translation initiation [J].Journal of Molecular Biology,2009,394(2):268-285.
[11] EFFRAIM PR,WANG J,ENGLANDER MT,et al.Natural amino acids do not require their native tRNAs for efficient selection by the ribosome [J].Nature Chemical Biology,2009,5(12):947-953.
[12] DALE T,FAHLMAN RP,OLEJNICZAK M,et al.Specificity of the ribosomal A site for aminoacyl-tRNAs [J].Nucleic Acids Research,2009,37(4):1202-1210.
[13] ZAHER HS,GREEN R.Quality control by the ribosome following peptide bond formation [J].Nature,2009,457(7226):161-166.