119例肺结核合并肠结核患者营养干预的疗效分析
|
摘要
目的:研究肺结核病合并肠结核患者营养状况及营养干预疗效。方法:收集大理大学第六附属医院肺结核合并肠结核患者119例为观察组,同时随机选取大理大学第六附属医院住院的213例肺结核患者作为对照组。进行营养风险(NRS)评估,记录服抗结核药后副作用。结果:观察组营养状况各项指标均较对照组低,在经营养干预及抗结核治疗后,两组营养风险显示均有好转;对照组明显好于观察组,差异有统计学意义(P<0.01),对照组治疗时间明显少于观察组,差异有统计学意义(P<0.01);对照组及观察组服抗结核药后胃肠反应、肝损害发生率差异有统计学意义(P<0.05)。结论:肺结核合并肠结核患者抗结核同时应注意休息与营养作为治疗基础,以更好完成疗程,减少并发症、减少住院时间、减轻患者经济负担。
Objective: To study the nutritional status and the effectiveness of nutritional intervention of the patients suffering from pulmonary tuberculosis(PTB) complicated with intestinal tuberculosis. Methods: 119 PTB complicated with intestinal tuberculosis patients treated in the Sixth Affiliated Hospital of Dali University were chosen as the observation group, and 213 PTB patients hospitalized in the same hospital were chosen as the control group. Nutritional risk screening was conducted and side effects caused by anti-tuberculosis drugs were recorded. Results: The nutritional status indicators of the observation group were lower than those of the control group and the nutritional risk of both groups showed improvement after nutritional intervention and anti-tuberculosis treatment;the control group was significantly better than that of the observation group, with significant difference(P<0.01). Length of treatment time of the control group was significantly shorter than that of the observation group, with significant difference(P<0.01). There was significant difference in incidence of gastrointestinal reactions and liver damage caused by anti-tuberculosis drugs between the observation group and the control group(P<0.05). Conclusion: In addition to receiving anti-tuberculosis therapy, patients suffering from PTB complicated with intestinal tuberculosis should rest well and maintain good nutrition to support completion of treatment,reduce complications, shorten hospital stays, and reduce economic burden.
Objective: To study the nutritional status and the effectiveness of nutritional intervention of the patients suffering from pulmonary tuberculosis(PTB) complicated with intestinal tuberculosis. Methods: 119 PTB complicated with intestinal tuberculosis patients treated in the Sixth Affiliated Hospital of Dali University were chosen as the observation group, and 213 PTB patients hospitalized in the same hospital were chosen as the control group. Nutritional risk screening was conducted and side effects caused by anti-tuberculosis drugs were recorded. Results: The nutritional status indicators of the observation group were lower than those of the control group and the nutritional risk of both groups showed improvement after nutritional intervention and anti-tuberculosis treatment;the control group was significantly better than that of the observation group, with significant difference(P<0.01). Length of treatment time of the control group was significantly shorter than that of the observation group, with significant difference(P<0.01). There was significant difference in incidence of gastrointestinal reactions and liver damage caused by anti-tuberculosis drugs between the observation group and the control group(P<0.05). Conclusion: In addition to receiving anti-tuberculosis therapy, patients suffering from PTB complicated with intestinal tuberculosis should rest well and maintain good nutrition to support completion of treatment,reduce complications, shorten hospital stays, and reduce economic burden.
引文
[1]马皎洁,安军,贺红,等.结核病患者营养状况及营养支持研究进展[J].中国防痨杂志,2016,38(11):995-999.
[2]叶任高,陆再英.内科学[M].北京:人民卫生出版社,2004:843.
[3]张培元.肺结核诊断和治疗指南[J].中华结核和呼吸杂志,2001,24(2):70-74.
[4]DE LUIS D A,LOPEZ M R,GONZALEZ S M,et al.Nuteitional status in a multicenter study among institutionalized patients in Spain[J].European Review for Medical and Pharmacological Sciences,2011,22:1095-1096.
[5]于康.临床营养治疗学[M].北京:中国协和医科大学出版社,2004:154-193.
[6]吕菁,隋向前,徐颖,等.585例成年住院结核病人营养状态调查[J].中国防痨杂志,2008,30(4):325-328.
[7]葛均波,徐永健.内科学[M].北京:人民卫生出版社,2008:379-382.
[8]LOCHS H,ALLISON S P,MEIER R,et al.Introductory to the ESPEN Guidelines on Enteral Nutrition:Terminology,definitions and general topics[J].Clin Nutr,2006,25(2):180-186.
[9]谭守勇,林兆原,关玉华,等.蛋白质营养不良对抗结核药物肝损害的影响[J].中国防痨杂志,2006,28(2):83-86.
[10]蒋朱明,于康,李海龙.营养支持对有营养风险患者结局的影响[J].中华临床营养杂志,2010,18(5):263-267.
[2]叶任高,陆再英.内科学[M].北京:人民卫生出版社,2004:843.
[3]张培元.肺结核诊断和治疗指南[J].中华结核和呼吸杂志,2001,24(2):70-74.
[4]DE LUIS D A,LOPEZ M R,GONZALEZ S M,et al.Nuteitional status in a multicenter study among institutionalized patients in Spain[J].European Review for Medical and Pharmacological Sciences,2011,22:1095-1096.
[5]于康.临床营养治疗学[M].北京:中国协和医科大学出版社,2004:154-193.
[6]吕菁,隋向前,徐颖,等.585例成年住院结核病人营养状态调查[J].中国防痨杂志,2008,30(4):325-328.
[7]葛均波,徐永健.内科学[M].北京:人民卫生出版社,2008:379-382.
[8]LOCHS H,ALLISON S P,MEIER R,et al.Introductory to the ESPEN Guidelines on Enteral Nutrition:Terminology,definitions and general topics[J].Clin Nutr,2006,25(2):180-186.
[9]谭守勇,林兆原,关玉华,等.蛋白质营养不良对抗结核药物肝损害的影响[J].中国防痨杂志,2006,28(2):83-86.
[10]蒋朱明,于康,李海龙.营养支持对有营养风险患者结局的影响[J].中华临床营养杂志,2010,18(5):263-267.