尼卡地平控制性降压在老年患者鼻内窥镜手术中的应用
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摘要
目的在老年患者鼻内窥镜手术中应用尼卡地平控制性降压可行性的临床观察。方法选择来本院就诊择期全麻老年鼻内窥镜手术患者60例,随机分组:实验组(尼卡地平组)、对照组(非尼卡地平组)。实验组实施静脉泵注尼卡地平;对照组静脉泵注等剂量的生理盐水。结果两组病例对比发现实验组心率在各个监测节点差异无统计学意义。对照组在控制性降压期间、停止降压后5 min、停止降压后10 min差异具有统计学意义。结论在老年患者鼻内窥镜手术中应用尼卡地平控制性降压能有效控制血压,可提高手术质量。
Objective To observe the clinical feasibility of controlled depressurization of nicardipine in elderly patients undergoing endoscopic sinus surgery. Methods Sixty patients undergoing elective general anesthesia for endoscopic sinus surgery were randomly divided into the experimental group(nicadipine group) and the control group(non-nikadipine group). The experimental group was treated with intravenous injection of nicardipine; the control group was intravenously injected with an equal dose of normal saline. Results Compared with the two groups, the heart rate of the experimental group was not statistically different at each monitoring node. The control group had statistical significance during controlled hypotension, 5 min after stopping blood pressure, and 10 min after stopping blood pressure. Conclusion The use of nicardipine controlled hypotension in elderly patients undergoing endoscopic sinus surgery can effectively control blood pressure and improve the quality of surgery.
Objective To observe the clinical feasibility of controlled depressurization of nicardipine in elderly patients undergoing endoscopic sinus surgery. Methods Sixty patients undergoing elective general anesthesia for endoscopic sinus surgery were randomly divided into the experimental group(nicadipine group) and the control group(non-nikadipine group). The experimental group was treated with intravenous injection of nicardipine; the control group was intravenously injected with an equal dose of normal saline. Results Compared with the two groups, the heart rate of the experimental group was not statistically different at each monitoring node. The control group had statistical significance during controlled hypotension, 5 min after stopping blood pressure, and 10 min after stopping blood pressure. Conclusion The use of nicardipine controlled hypotension in elderly patients undergoing endoscopic sinus surgery can effectively control blood pressure and improve the quality of surgery.
引文
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[9]黄培龙,刘琳琳,陈宇,等.尼卡地平与瑞芬太尼对老年鼻内镜手术患者控制性降压期间脑氧代谢的影响[J].转化医学杂志,2017,6(2):91-93.
[10]胡志强,黄勇辉.尼卡地平复合硝酸甘油在鼻内窥镜手术控制性降压的应用[J].现代医院,2015(1):43-44.
[11]陈碧岚,胡耿平,欧阳海清.尼卡地平复合艾司洛尔控制性降压用于鼻内镜手术的效果观察[J].海峡药学,2009,21(10):125-126.
[12]国松,郭旭东.右美托咪定复合尼卡地平在全身麻醉鼻内镜手术控制性降压的应用[J].中国现代药物应用,2015(19):135-136.
[13]高东艳.尼卡地平和艾络用于鼻内镜术中控制性降压的研究[J].临床医药实践,2004,13(6):415-416.
[2]郭宗锋.瑞芬太尼和舒芬太尼用于妇科腹腔镜手术围拔管期血流动力学的比较[J].河北联合大学学报(医学版),2016.2(18):104-106.
[3]陈伯銮.临床麻醉药理学[M].北京:人民卫生出版社,2000.
[4]李文红,刘进德,边小松,等.不同剂量右美托咪定复合瑞芬太尼-丙泊酚控制性降压在鼻内窥镜手术中的应用效果[J].河北医药,2018,2(40):535-538.
[5]张红芹,郑静,徐璐,等.右美托咪定复合尼卡地平用于鼻内镜手术控制性降压临床研究[J].中国药业,2016,25(7):33-35.
[6]周峰,蔡秋萍,张延钧,等.尼卡地平在鼻内窥镜手术控制性降压中的应用[J].大连医科大学学报,2001,23(2):110-111.
[7]李振华,蔡宏伟,田志海,等.尼卡地平复合艾司洛尔在鼻内镜手术控制性降压中的效果[J].中国医学工程,2004,12(6):19-21.
[8]雅健,张国栓.尼卡地平和盐酸乌拉地尔控制性降压在鼻内镜手术中的应用[J].河北医药,2006,28(4):282-283.
[9]黄培龙,刘琳琳,陈宇,等.尼卡地平与瑞芬太尼对老年鼻内镜手术患者控制性降压期间脑氧代谢的影响[J].转化医学杂志,2017,6(2):91-93.
[10]胡志强,黄勇辉.尼卡地平复合硝酸甘油在鼻内窥镜手术控制性降压的应用[J].现代医院,2015(1):43-44.
[11]陈碧岚,胡耿平,欧阳海清.尼卡地平复合艾司洛尔控制性降压用于鼻内镜手术的效果观察[J].海峡药学,2009,21(10):125-126.
[12]国松,郭旭东.右美托咪定复合尼卡地平在全身麻醉鼻内镜手术控制性降压的应用[J].中国现代药物应用,2015(19):135-136.
[13]高东艳.尼卡地平和艾络用于鼻内镜术中控制性降压的研究[J].临床医药实践,2004,13(6):415-416.