2003-2012年江苏省胃癌发病死亡及农村地区生存情况分析
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摘要
目的了解2003-2012年江苏省胃癌发病死亡流行水平,分析2003-2005年江苏农村地区新发胃癌患者的生存情况。方法收集2003-2012年江苏省的肿瘤登记数据,按照年份、年龄分层,使用粗率、中国人口标化率(中标率)和世界人口标化率(世标率)描述胃癌的发病及死亡情况,并计算发病率及死亡率的年度变化百分比(annual percent change,APC)。随访2003-2005年江苏农村地区胃癌发病的患者信息,按不同性别、年龄分组计算其观察生存率和相对生存率,分析不同组别间的生存情况差异。结果 2003-2012年江苏省肿瘤登记地区胃癌年平均发病率为48.2/10万,中标率为32.0/10万。同期胃癌年平均死亡率为35.1/10万,中标率为22.5/10万。2003-2012年胃癌发病率和死亡率均明显下降。2003-2005年江苏农村地区新发胃癌病人5年观察生存率为21.8%,相对生存率为25.1%,生存率男性高于女性,随年龄增长呈下降趋势。结论 2003-2012年江苏省胃癌发病率及死亡率均明显下降,但仍处于较高水平,且患者预后较差。加强上消化道癌筛查,提高早期检出率是改善生存率的重要手段之一。
Objective To describe the incidence,mortality of stomach cancer and to analyze its survival status in the rural place of Jiangsu Province,China.Methods Population-based cancer registry data during 2003-2012 were collected.Stratified by age and year,crude rates,age-standardized rates by Chinese population( ASRC) and age-standardized rates by world population( ASRW) were used to describe incidence and mortality in Jiangsu.Annual percent change( APC) was calculated to estimate the changing trend from 2003 to 2012.Patients diagnosed between 2003 and 2005 were chosen for analyzing the survival status of stomach cancer,observed survival rate( OSR) and relative survival rate( RSR)were calculated according to different sex and age groups to analyze the differences.Results From 2003 to 2012,the crude incidence rate of stomach cancer was 48.2/100 000,ASRC was 32.0/100 000.During the same period,the crude mortality rate was 35.1/100 000,ASRC was 22.5/100 000.From 2003 to 2012,the incidence and mortality were significantly decreased.For survival analysis of rural place,the 5-year observed survival rate of cases was 21.8% and relative survival rate was 25.1%.Survival rates were found to decrease with more survival years,higher in males,and decreased with age.Conclusions The incidence and mortality of stomach cancer in Jiangsu Province were significantly decreased from 2003 to 2012,but still at higher level,and its survival status was poor.More resources should be put to early screening,which is one of the most effective ways to improve cancer survival status.
Objective To describe the incidence,mortality of stomach cancer and to analyze its survival status in the rural place of Jiangsu Province,China.Methods Population-based cancer registry data during 2003-2012 were collected.Stratified by age and year,crude rates,age-standardized rates by Chinese population( ASRC) and age-standardized rates by world population( ASRW) were used to describe incidence and mortality in Jiangsu.Annual percent change( APC) was calculated to estimate the changing trend from 2003 to 2012.Patients diagnosed between 2003 and 2005 were chosen for analyzing the survival status of stomach cancer,observed survival rate( OSR) and relative survival rate( RSR)were calculated according to different sex and age groups to analyze the differences.Results From 2003 to 2012,the crude incidence rate of stomach cancer was 48.2/100 000,ASRC was 32.0/100 000.During the same period,the crude mortality rate was 35.1/100 000,ASRC was 22.5/100 000.From 2003 to 2012,the incidence and mortality were significantly decreased.For survival analysis of rural place,the 5-year observed survival rate of cases was 21.8% and relative survival rate was 25.1%.Survival rates were found to decrease with more survival years,higher in males,and decreased with age.Conclusions The incidence and mortality of stomach cancer in Jiangsu Province were significantly decreased from 2003 to 2012,but still at higher level,and its survival status was poor.More resources should be put to early screening,which is one of the most effective ways to improve cancer survival status.
引文
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[16]陈万青,郑荣寿,曾红梅,等.1989-2008年中国恶性肿瘤发病趋势分析[J].中华肿瘤杂志,2012,34(7):525-531.
[17]郭康,周脉耕,潘晓平.中国居民2006-2012年胃癌死亡趋势分析[J].中国公共卫生,2015,31(3):341-343.
[18]Zeng H,Zheng R,Guo Y,et al.Cancer survival in China,2003-2005:a population-based study[J].Int J Cancer,2015,136(8):1921-1930.
[19]龚巍巍,罗胜兰,胡如英,等.2005-2010年浙江省胃癌生存率分析[J].中华肿瘤杂志,2014,36(8):636-639.
[20]Tolentino CA,Ojeda DV.Survival rate of patients with stomach cancer in Peru,2009-2010[J].Rev Panam Salud Pública,2015,37(3):133-139.
[21]Dudeja V,Habermann EB,Zhong W,et al.Guideline recommended gastric cancer care in the elderly:insights into the applicability of cancer trials to real world[J].Ann Surg Oncol,2011,18(1):26-33.
[22]Crew KD,Neugut AI.Epidemiology of gastric cancer[J].World J Gastroenterol,2006,12(3):354-362.
[2]张思维,陈万青,郑荣寿,等.2003-2007年中国癌症死亡分析[J].中国肿瘤,2012,21(3):171-178.
[3]韩仁强,武鸣,俞浩,等.2010年江苏省肿瘤登记地区恶性肿瘤发病与死亡[J].江苏预防医学,2015,26(1):5-10.
[4]郑朝旭,郑荣寿,陈万青.中国2009年胃癌发病与死亡分析[J].中国肿瘤,2013,22(5):327-332.
[5]周金意,武鸣,杨婕,等.1973-2010年江苏省居民恶性肿瘤死亡率变化趋势[J].中国肿瘤,2012,21(8):570-573.
[6]苏靖,周正元,张宁,等.江苏省常熟市2008-2011年胃癌患者生存率分析[J].江苏预防医学,2014,25(4):63-64.
[7]姚海蓉,陈豪,陈建国,等.启东地区肝癌生存率长期趋势分析[J].中华肝脏病杂志,2014,22(12):921-925.
[8]项永兵,张薇,高立峰,等.恶性肿瘤发病率的时间趋势分析方法[J].中华流行病学杂志,2004,25(2):173-177.
[9]Jensen,Ole Mller.Cancer registration:principles and methods[M].IARC,1991.
[10]Dickman PW,Coviello E,Hills M.Estimating and modeling relative survival[J].Stata J,2015,15(1):186-215.
[11]Chia SE,Tan CS,Lim GH,et al.Incidence,mortality and survival patterns of prostate cancer among residents in Singapore from1968 to 2002[J].BMC Cancer,2008,8:368.
[12]Corazziari I,Quinn M,Capocaccia R.Standard cancer patient population for age standardising survival ratios[J].Eur J Cancer,2004,40(15):2307-2316.
[13]陈万青,郑荣寿,张思维,等.2012年中国恶性肿瘤发病和死亡分析[J].中国肿瘤,2016,25(1):1-8.
[14]王悠清,杜灵彬,李辉章,等.浙江省肿瘤登记地区2012年恶性肿瘤发病与死亡分析[J].中国肿瘤,2016,25(1):9-19.
[15]王晓辉,张小栋,李辉玲,等.2005-2007年兰州市恶性肿瘤发病状况分析[J].中华疾病控制杂志,2012,16(2):113-116.
[16]陈万青,郑荣寿,曾红梅,等.1989-2008年中国恶性肿瘤发病趋势分析[J].中华肿瘤杂志,2012,34(7):525-531.
[17]郭康,周脉耕,潘晓平.中国居民2006-2012年胃癌死亡趋势分析[J].中国公共卫生,2015,31(3):341-343.
[18]Zeng H,Zheng R,Guo Y,et al.Cancer survival in China,2003-2005:a population-based study[J].Int J Cancer,2015,136(8):1921-1930.
[19]龚巍巍,罗胜兰,胡如英,等.2005-2010年浙江省胃癌生存率分析[J].中华肿瘤杂志,2014,36(8):636-639.
[20]Tolentino CA,Ojeda DV.Survival rate of patients with stomach cancer in Peru,2009-2010[J].Rev Panam Salud Pública,2015,37(3):133-139.
[21]Dudeja V,Habermann EB,Zhong W,et al.Guideline recommended gastric cancer care in the elderly:insights into the applicability of cancer trials to real world[J].Ann Surg Oncol,2011,18(1):26-33.
[22]Crew KD,Neugut AI.Epidemiology of gastric cancer[J].World J Gastroenterol,2006,12(3):354-362.