逍遥散结合生物反馈治疗肝郁气滞型功能性肛门直肠痛30例
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摘要
目的:探究逍遥散结合生物反馈治疗肝郁气滞型功能性肛门直肠痛的临床疗效。方法:选取就诊于本院的肝郁气滞型功能性肛门直肠痛患者60例,随机分为观察组和对照组各30例。两组均应用生物反馈进行治疗,其中观察组联用逍遥散口服及灌肠,共治疗30d,比较两组治疗前后VAS评分、盆底表面肌电值、总有效率等,以此评定两种治疗方案的临床疗效。结果:治疗后观察组较对照组总有效率、快速收缩AVG Peak、间断收缩AVG明显升高,差异具有统计学意义(P <0. 05);疼痛视觉模拟评分、放松状态AVG、肌电变异性CV显著降低,差异具有统计学意义(P <0. 05)。结论:逍遥散结合生物反馈对缓解肝郁气滞型功能性肛门直肠痛症状、提高患者生活质量效果显著。
Objective: To explore the clinical efficacy of xiaoyao powder combined with biofeedback in the therapy of functional anorectal pain with type of liver depression and qi stagnation. Methods: 60 patients with type of liver depression and Qi stagnation type of functional anorectal pain who were admitted to the First Affiliated Hospital of Anhui University of Chinese Medicine were selected. Both groups used biofeedback,and the observation group was treated with Xiaoyao powder oral and enema for a total of 30 days,and the VAS score,facial electromyography value and the overall efficiency were compared before and after treatment,so as to evaluate the clinical efficacy of the two treatment options. Results: After treatment,the overall efficiency,rapid contraction AVG Peak and intermittent contraction AVG of the observation group were dramatically higher than those of the control group( P < 0. 05). Visual analogue scores,relaxation AVG and emg CV were significantly reduced,with observably differences( P < 0. 05). Conclusion: Xiaoyao powder combined with biofeedback has significant effects on the improvement and prognosis of functional anorectal pain with liver depression and qi stagnation,and can markedly enhanced the quality of life of patients.
Objective: To explore the clinical efficacy of xiaoyao powder combined with biofeedback in the therapy of functional anorectal pain with type of liver depression and qi stagnation. Methods: 60 patients with type of liver depression and Qi stagnation type of functional anorectal pain who were admitted to the First Affiliated Hospital of Anhui University of Chinese Medicine were selected. Both groups used biofeedback,and the observation group was treated with Xiaoyao powder oral and enema for a total of 30 days,and the VAS score,facial electromyography value and the overall efficiency were compared before and after treatment,so as to evaluate the clinical efficacy of the two treatment options. Results: After treatment,the overall efficiency,rapid contraction AVG Peak and intermittent contraction AVG of the observation group were dramatically higher than those of the control group( P < 0. 05). Visual analogue scores,relaxation AVG and emg CV were significantly reduced,with observably differences( P < 0. 05). Conclusion: Xiaoyao powder combined with biofeedback has significant effects on the improvement and prognosis of functional anorectal pain with liver depression and qi stagnation,and can markedly enhanced the quality of life of patients.
引文
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[2]苏芳,盖成林,孙正清.右美托咪定联合瑞芬太尼用于甲状腺腺瘤手术清醒镇静麻醉效果观察[J].人民军医,2015,58(4):389-391.
[3]吴天福,耿学斯.功能性肛门直肠痛的治疗研究进展[J].甘肃中医学院学报,2015,32(2):81-83.
[4]Bharueha AE.Junctional Anorectal Disorders[J].Gastroenterology,2006,130(5):1 510-1 518.
[5]王业皇,郑春菊,章阳.丁泽民治疗功能性肛门直肠痛的经验[J].江苏中医药,2013,45(2):4-5.
[6]Dwarkasing RS,Schouten WR,Geeraedts TE,et al.Chronic anal and perianal pain resolved with MRI[J].American Journal of Roentgenology,2013,200(5):1 034-1 041.
[7]中华人民共和国卫生部.中药新药临床研究指导原则[M].北京:中国中医药出版社.1993:28-31.
[8]薛雅红,丁曙晴.功能性肛门直肠痛患者盆底表面肌电的检测及临床意义[J].实用医学杂志,2012,28(11):1 803-1 806.
[9]Boyce PM,Talley NJ,Burke C,et al.Epidemiology of the functional gastrointestinal disorders diagnosed according to RomeⅡcriteria:an Australian population-based study[J].Intern Med J,2006,36(1):28-36.
[10]陆铤,薛雅红,丁曙晴,等.针灸治疗慢性肛门直肠痛[J].世界华人消化杂志,2014,22(7):951-955.
[11]Gilliland R,Heymen JS,Altomare DF,et al,Biofeedback for intractable rectalpain:outcome and predictors of success[J].Dis Colon Rectum,1997(40):190-196.
[12]谢东浩,贾晓斌,蔡宝昌,等.北柴胡及春柴胡挥发油的抗炎镇痛作用的实验研究[J].药学临床研究,2007,15(2):108-110.
[13]张廷模.临床中药学[M].上海:上海科学技术出版社,2006:85-320.
[14]王志旺,魏舒畅,冯祥瑞,等.不同提取工艺所得当归精油镇痛抗炎作用的对比研究[J].中药药理与临床,2012,28(5):87-90.
[15]吴修红,胡妮娜,李宝龙,等.赤芍与白芍脐中穴给药的药理作用比较研究[J].针灸临床杂志,2014,24(5):54-56.