曼月乐与子宫楔切术治疗子宫腺肌症的临床效果对比研究
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摘要
目的:研究子宫腺肌症患者分别应用子宫楔切术和曼月乐治疗的临床效果。方法:选取2015年6月-2016年6月本院收治的子宫肌腺症患者60例,按照随机数字表法将其分为研究组和对照组,每组30例。对照组应用曼月乐治疗,研究组应用子宫楔切术治疗,对比两组相关的临床指标。结果:治疗后6个月,研究组子宫体积缩小率明显高于对照组(P<0.05),两组痛经缓解率和月经改善率比较,差异均无统计学意义(P>0.05)。治疗后12个月,研究组患者痛经复发率和月经增多率均明显高于对照组(P<0.05),两组患者的子宫体积缩小率比较,差异无统计学意义(P>0.05)。结论:曼月乐和子宫楔切术均可被应用于子宫腺肌症的临床治疗中,近期临床治疗效果均相似,均能够有效缩小患者的子宫体积,达到预期临床治疗效果,但行曼月乐治疗的子宫腺肌症患者长远效果更好,在有效缩小患者子宫体积的同时可有效控制病症复发情况,有一定的安全性,在临床治疗中有重要意义。
Objective:To study the clinical effect of uterine wedge resection and Mirena in the treatment of patients with adenomyosis respectively.Method:60 cases of adenomyosis from June 2015 to June 2016 in our hospital were selected,according to the random number table method,they were randomly divided into the research group and the control group,30 cases in each group.The control group was treated with Mirena and the research group was treated with uterine wedge resection,the relevant clinical indexes of two groups were compared.Result:6 months after treatment,the reduction rate of uterine volume in the research group was significantly higher than that of the control group(P<0.05),the dysmenorrhea remission rate and menstrual improvement rate were compared of two groups,the differences were not statistically significant(P>0.05).12 months after treatment,the rate of relapse and menstruation in the research group were significantly higher than those of the control group(P<0.05),the uterine volume reduction ratio were compared of two groups,the difference was not statistically significant(P>0.05).Conclusion:Both Mirena and uterine wedge resection can be applied to the clinical treatment of adenomyosis with similar clinical treatment effect recently,they can effectively reduce patients' uterine volume and reach the expected clinical treatment effect,however,the long-term curative of the patients with adenomyosis is better,can effectively control the disease recurrence in patients with uterine volume shorten at the same time,there is a certain security,it is of great significance in clinical treatment.
Objective:To study the clinical effect of uterine wedge resection and Mirena in the treatment of patients with adenomyosis respectively.Method:60 cases of adenomyosis from June 2015 to June 2016 in our hospital were selected,according to the random number table method,they were randomly divided into the research group and the control group,30 cases in each group.The control group was treated with Mirena and the research group was treated with uterine wedge resection,the relevant clinical indexes of two groups were compared.Result:6 months after treatment,the reduction rate of uterine volume in the research group was significantly higher than that of the control group(P<0.05),the dysmenorrhea remission rate and menstrual improvement rate were compared of two groups,the differences were not statistically significant(P>0.05).12 months after treatment,the rate of relapse and menstruation in the research group were significantly higher than those of the control group(P<0.05),the uterine volume reduction ratio were compared of two groups,the difference was not statistically significant(P>0.05).Conclusion:Both Mirena and uterine wedge resection can be applied to the clinical treatment of adenomyosis with similar clinical treatment effect recently,they can effectively reduce patients' uterine volume and reach the expected clinical treatment effect,however,the long-term curative of the patients with adenomyosis is better,can effectively control the disease recurrence in patients with uterine volume shorten at the same time,there is a certain security,it is of great significance in clinical treatment.
引文
[1]马启敏.腹腔镜子宫楔形切除术联合曼月乐治疗对子宫腺肌病患者临床疗效及生活质量的影响[J].临床心身疾病杂志,2017,23(3):72-74.
[2]钟富琴.节育器药物局部缓释治疗与子宫楔切术对子宫腺肌症的临床疗效对比研究[J].浙江创伤外科,2013,18(5):694-695.
[3]游玉梅.腹腔镜子宫楔形切除术并术后阴道置放曼月乐治疗子宫腺肌病效果观察[J].心理医生,2017,23(10):4-5.
[4]陈美容,方丽珊,魏和鸣,等.子宫腺肌瘤剔除术联合曼月乐宫腔置入治疗子宫腺肌瘤的疗效分析[J].中外医疗,2015,34(26):42-43.
[5]陈桂芳.腹腔镜子宫楔形切除术并术后阴道置放曼月乐治疗子宫腺肌病疗效[J].临床医药文献电子杂志,2017,4(7):1201.
[6]毛力旦·买买提江,古孜娜·赛尔山别克.腹腔镜子宫楔形切除术联合术后使用曼月乐(阴道置放)治疗子宫腺肌病效果观察[J].实用妇科内分泌电子杂志,2016,3(18):143.
[7]彭燕蓁,段华,郭银树,等.子宫腺肌病灶切除术联合曼月乐的临床疗效评价[J].中华临床医师杂志(电子版),2016,10(24):3689-3692.
[8]雷庆华,龚翠梅,李丽琴,等.保留子宫功能的子宫肌层大部切除术联合曼月乐治疗重度子宫腺肌病临床分析[J].中国现代医学杂志,2014,24(16):82-84.
[9]钟颖,黄紫蓉.200例子宫肌腺症患者放置曼月乐术后加用避孕药对防治不规则阴道流血的作用分析[J].中国初级卫生保健,2014,28(10):60-62.
[10]张凤格,米鑫.曼月乐治疗子宫腺肌病所致月经量增多及中重度痛经的临床疗效观察[J].生殖医学杂志,2015,24(6):494-496.
[11]李扬,刘贵鹏,俞丽娜,等.腹腔镜下子宫体楔形切除术对术后生活质量的影响[J].中国医科大学学报,2014,43(4):368-371.
[12]谢承志,陈艾丽,曾凡强,等.子宫壁梭形切除术治疗子宫腺肌病疗效观察-附180例病例分析[J].中国计划生育和妇产科,2016,8(9):55-58.
[13]朱莹莹,范盈盈.腹腔镜下宫角妊娠部位楔形切除修补术在宫角妊娠中的临床应用[J].现代实用医学,2014,26(9):1137-1139.
[14]陈富强,张爱凤,王小波,等.子宫内膜电切术联合左炔诺孕酮宫内节育系统治疗子宫腺肌病的前瞻性研究[J].上海交通大学学报(医学版),2017,37(5):641-645.
[15]仝蕊,赵兴元,雷俊华,等.超声对曼月乐环治疗子宫腺肌病的临床疗效观察[J].昆明医科大学学报,2015,36(5):136-138.
[16]孔嫦瑛.曼月乐治疗痛经及经量增多的子宫腺肌症126例分析[J].中国妇幼保健,2015,30(23):4067-4068.
[17]陈奇,杨丽娟.曼月乐宫内节育器治疗子宫腺肌症近远期临床疗效分析[J].中国妇幼保健,2014,29(8):1278-1280.
[18]方德容,赵菁,李青汉,等.曼月乐治疗子宫腺肌病病灶阈值筛选的初步研究[J].遵义医学院学报,2014,37(4):418-421.
[2]钟富琴.节育器药物局部缓释治疗与子宫楔切术对子宫腺肌症的临床疗效对比研究[J].浙江创伤外科,2013,18(5):694-695.
[3]游玉梅.腹腔镜子宫楔形切除术并术后阴道置放曼月乐治疗子宫腺肌病效果观察[J].心理医生,2017,23(10):4-5.
[4]陈美容,方丽珊,魏和鸣,等.子宫腺肌瘤剔除术联合曼月乐宫腔置入治疗子宫腺肌瘤的疗效分析[J].中外医疗,2015,34(26):42-43.
[5]陈桂芳.腹腔镜子宫楔形切除术并术后阴道置放曼月乐治疗子宫腺肌病疗效[J].临床医药文献电子杂志,2017,4(7):1201.
[6]毛力旦·买买提江,古孜娜·赛尔山别克.腹腔镜子宫楔形切除术联合术后使用曼月乐(阴道置放)治疗子宫腺肌病效果观察[J].实用妇科内分泌电子杂志,2016,3(18):143.
[7]彭燕蓁,段华,郭银树,等.子宫腺肌病灶切除术联合曼月乐的临床疗效评价[J].中华临床医师杂志(电子版),2016,10(24):3689-3692.
[8]雷庆华,龚翠梅,李丽琴,等.保留子宫功能的子宫肌层大部切除术联合曼月乐治疗重度子宫腺肌病临床分析[J].中国现代医学杂志,2014,24(16):82-84.
[9]钟颖,黄紫蓉.200例子宫肌腺症患者放置曼月乐术后加用避孕药对防治不规则阴道流血的作用分析[J].中国初级卫生保健,2014,28(10):60-62.
[10]张凤格,米鑫.曼月乐治疗子宫腺肌病所致月经量增多及中重度痛经的临床疗效观察[J].生殖医学杂志,2015,24(6):494-496.
[11]李扬,刘贵鹏,俞丽娜,等.腹腔镜下子宫体楔形切除术对术后生活质量的影响[J].中国医科大学学报,2014,43(4):368-371.
[12]谢承志,陈艾丽,曾凡强,等.子宫壁梭形切除术治疗子宫腺肌病疗效观察-附180例病例分析[J].中国计划生育和妇产科,2016,8(9):55-58.
[13]朱莹莹,范盈盈.腹腔镜下宫角妊娠部位楔形切除修补术在宫角妊娠中的临床应用[J].现代实用医学,2014,26(9):1137-1139.
[14]陈富强,张爱凤,王小波,等.子宫内膜电切术联合左炔诺孕酮宫内节育系统治疗子宫腺肌病的前瞻性研究[J].上海交通大学学报(医学版),2017,37(5):641-645.
[15]仝蕊,赵兴元,雷俊华,等.超声对曼月乐环治疗子宫腺肌病的临床疗效观察[J].昆明医科大学学报,2015,36(5):136-138.
[16]孔嫦瑛.曼月乐治疗痛经及经量增多的子宫腺肌症126例分析[J].中国妇幼保健,2015,30(23):4067-4068.
[17]陈奇,杨丽娟.曼月乐宫内节育器治疗子宫腺肌症近远期临床疗效分析[J].中国妇幼保健,2014,29(8):1278-1280.
[18]方德容,赵菁,李青汉,等.曼月乐治疗子宫腺肌病病灶阈值筛选的初步研究[J].遵义医学院学报,2014,37(4):418-421.