初治鼻咽癌调强放射治疗与常规放射治疗近期疗效
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摘要
目的研究初治鼻咽癌调强放射治疗与常规放射治疗近期疗效与副反应。方法选择2015年9月—2017年9月到院就诊的初治鼻咽癌患者116例,随机分为对照组和观察组,每组58例。对照组常规放射治疗,观察组调强放射治疗。对比两组近期疗效及副反应。结果观察组总有效率93.10%(54/58),高于对照组的75.86%(44/58)(P <0.05)。观察组副反应率10.34%(6/58),低于对照组的27.59%(16/58)(P <0.05)。结论对初治鼻咽癌患者,采用调强放射治疗方法,近期疗效更理想,副反应更少。
Objective To study the short-term efficacy and side effects of intensity modulated radiotherapy(IMRT) and conventional radiotherapy for nasopharyngeal carcinoma(NPC). Methods 116 patients with nasopharyngeal carcinoma from September 2015 to September 2017 were randomly divided into control group(n = 58) and observation group(n = 58). The control group was treated with conventional radiotherapy and the observation group with intensity modulated radiotherapy. The short-term curative effect and side effects were compared between the two groups. Results The total effective rate of the observation group was 93.10%(54/58), which was higher than that of the control group 75.86%(44/58)(P < 0.05). The side effect rate of the observation group was 10.34%(6/58), which was lower than that of the control group of 27.59%(16/58)(P < 0.05). Conclusion For nasopharyngeal carcinoma patients, intensity modulated radiation therapy(IMRT) is more effective and less side effects.
Objective To study the short-term efficacy and side effects of intensity modulated radiotherapy(IMRT) and conventional radiotherapy for nasopharyngeal carcinoma(NPC). Methods 116 patients with nasopharyngeal carcinoma from September 2015 to September 2017 were randomly divided into control group(n = 58) and observation group(n = 58). The control group was treated with conventional radiotherapy and the observation group with intensity modulated radiotherapy. The short-term curative effect and side effects were compared between the two groups. Results The total effective rate of the observation group was 93.10%(54/58), which was higher than that of the control group 75.86%(44/58)(P < 0.05). The side effect rate of the observation group was 10.34%(6/58), which was lower than that of the control group of 27.59%(16/58)(P < 0.05). Conclusion For nasopharyngeal carcinoma patients, intensity modulated radiation therapy(IMRT) is more effective and less side effects.
引文
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[2]石兴源,艾亮梅,黄文瑾,等.尼妥珠单抗联合顺铂同期化疗治疗局部晚期鼻咽癌疗效[J].广州医学院学报,2016,44(5):42-47.
[3]于瑞莲,安宁,兰海涛,等.胎盘多肽注射液联合放化疗治疗中晚期鼻咽癌的疗效观察[J].西部医学,2016,28(9):1227-1229,1233.
[4]满宪凤,范廷勇,邢军,等.鼻咽癌同步推量调强放疗与传统调强放疗的近远期疗效比较[J].中华肿瘤防治杂志,2016,23(4):244-247.
[5]叶大胜,周耀军,方伟达,等.初治鼻咽癌调强放疗与常规放疗的同期对照研究[J].当代临床医刊,2017,30(4):3211,3208.
[6]孟凡军,陈育标,庄梅生.早期乳腺癌保留乳房手术后全乳腺大分割与常规分割放疗的疗效和毒副反应比较[J].海南医学,2017,28(12):2024-2025.
[7]胡晓菲,汪俊,王钢胜.TPF方案诱导时间调节化疗对局部晚期鼻咽癌的近期疗效、毒副反应和患者免疫功能的影响[J].河北医药,2016,38(23):3541-3544.
[8]麻发强.洛铂联合放疗与顺铂联合放疗治疗鼻咽癌的近期疗效与毒副反应对比[J].当代医药论丛,2017,15(16):134-135.
[9]杨大琼.初治非小细胞肺癌调强放疗与常规放疗的同期对照研究[J].临床肺科杂志,2016,21(11):2121-2123.
[10]魏洁,王军,吕星旺.80岁以上老年人食管癌适形调强放疗与常规放疗疗效比较[J].中华全科医学,2016,14(9):1488-1491.
[11]李坊铭,陈国健,王羽,等.60例初治鼻咽癌调强放疗近期疗效分析[J].海南医学,2016,27(14):2274-2277.
[12]慧妍.鼻咽癌常规放疗后两种不同推量方式的作用[J].中国继续医学教育,2017,9(14):159-161.
[13]孔琳,王磊,管西寅,等.碳离子调强放射治疗复发性局部晚期鼻咽癌的近期疗效及不良反应[J].中华放射医学与防护杂志,2016,36(8):601-606.