高血压与肠道菌群相关性研究文献计量学分析
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摘要
目的分析评价2008—2017年SCI收录的高血压与肠道菌群相关性研究的文献情况,为进一步开展该领域的研究提供参考。方法以Web of Science核心合集数据库为资料来源,选用Web of Science核心合集数据库中的高级检索,分别对高血压(hypertension)和肠道菌群(gut microbiota)的同义词、上下位类主题词采用布尔运算符"OR"组配,组间采用"AND"组配,字段标识符选择主题(TS);检索年限:2008—2017年;检索日期:2017-11-01;对高血压与肠道菌群相关性研究文献资料进行描述性统计分析。结果共纳入62篇文献。发文量从2015年开始逐年增多;Current Hypertension Reports发文最多(5篇);Circulation的影响因子最高(19.309);高被引文献(被引量≥9.02)有14篇;文献合作度7.29,文献合作率91.94%;发文量≥2篇的作者主要来自美国;有科研基金资助的文献48篇(77.42%);本研究共涉及88个关键词,研究方向以心血管系统与心脏病学为主,研究内容主要集中于肠道菌群失调与高血压的相关性。结论高血压与肠道菌群的相关性研究目前尚处于起步阶段,存在发文期刊分散、学术影响力小等不足,需对二者的因果关系、作用机制等关键问题继续探索、验证,在研究内容和研究质量上不断丰富和优化。
Objective To analyze and evaluate the literature on the correlation between hypertension and gut microbiota collected in SCI from 2008 to 2017,and to provide a reference for further research in this field.Methods The Web of Science Core Collection Databases were used as the data source,and the "Advanced Search" feature was used to retrieve the related literature.The synonym and hyponym or hypernym keywords related to "hypertension" and "gut microbiota" combined with the Boolean operator "OR",or the Boolean operator "AND" were used in the search,and "Topic"(TS) was chosen as the field tag.The searching period was 2008—2017,and the searching date was 2017-11-01.A descriptive statistical analysis was conducted on the literature on the correlation between hypertension and gut microbiota.Results A total of 62 papers were included.The number of published papers increased from 2015;the journal Current Hypertension Reports published the highest number(five papers),and Circulation had the highest impact index(19.309).There were 14 highly cited papers(cited ≥ 9.02).The degree of literature cooperation was 7.29,and the rate of literature cooperation was 91.94%.Authors who had two or more papers were mainly from the United States.There were 48 papers sponsored by funds(77.42%).The present study used 88 keywords.The research fields were primarily the cardiovascular system and cardiology,and the research content mainly focused on the relationship between intestinal dysbacteriosis and hypertension.Conclusion Research on the correlation between hypertension and gut microbiota is still in an early stage.There are some shortages,for example,academic influence is not strong.It is necessary to continue exploring and verifying key issues such as the causality and mechanisms underlying connections between hypertension and the gut microbiota.Research scope and quality must also expand and improve.
Objective To analyze and evaluate the literature on the correlation between hypertension and gut microbiota collected in SCI from 2008 to 2017,and to provide a reference for further research in this field.Methods The Web of Science Core Collection Databases were used as the data source,and the "Advanced Search" feature was used to retrieve the related literature.The synonym and hyponym or hypernym keywords related to "hypertension" and "gut microbiota" combined with the Boolean operator "OR",or the Boolean operator "AND" were used in the search,and "Topic"(TS) was chosen as the field tag.The searching period was 2008—2017,and the searching date was 2017-11-01.A descriptive statistical analysis was conducted on the literature on the correlation between hypertension and gut microbiota.Results A total of 62 papers were included.The number of published papers increased from 2015;the journal Current Hypertension Reports published the highest number(five papers),and Circulation had the highest impact index(19.309).There were 14 highly cited papers(cited ≥ 9.02).The degree of literature cooperation was 7.29,and the rate of literature cooperation was 91.94%.Authors who had two or more papers were mainly from the United States.There were 48 papers sponsored by funds(77.42%).The present study used 88 keywords.The research fields were primarily the cardiovascular system and cardiology,and the research content mainly focused on the relationship between intestinal dysbacteriosis and hypertension.Conclusion Research on the correlation between hypertension and gut microbiota is still in an early stage.There are some shortages,for example,academic influence is not strong.It is necessary to continue exploring and verifying key issues such as the causality and mechanisms underlying connections between hypertension and the gut microbiota.Research scope and quality must also expand and improve.
引文
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[14]吴晓秋,吕娜.基于关键词共现频率的热点分析方法研究[J].情报理论与实践,2012,35(8):115-119.WU X Q,LYU N.Research on the hot spot analysis method based on keyword co-occurrence frequency[J].Information Studies:Theory&Application,2012,35(8):115-119.
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[18]KOETH R A,WANG Z,LEVISON B S,et al.Intestinal microbiota metabolism of L-carnitine,a nutrient in red meat,promotes atherosclerosis[J].Nat Med,2013,19(5):576-585.DOI:10.1038/nm.3145.
[19]SANTISTEBAN M M,KIM S,PEPINE C J,et al.Braingut-bone marrow axis:implications for hypertension and related therapeutics[J].Circ Res,2016,118(8):1327-1336.DOI:10.1161/CIRCRESAHA.116.307709.
[20]李兰娟.国际人类微生物组最新研究进展——第五届国际人类微生物组联盟学术会议纪要[J].中华临床感染病杂志,2015,8(2):188-192.DOI:10.3760/cma.j.issn.1674-2397.2015.02.024.LI L J.Advances on human microbiome studies:summary of the 5th Internaltional Human Microbiome Congress[J].Chinese Journal of Clinical Infectious Diseases,2015,8(2):188-192.DOI:10.3760/cma.j.issn.1674-2397.2015.02.024.
[2]胡红卫,黄永坤.肠道菌群与相关疾病的研究进展[J].中国微生态学杂志,2017,29(1):106-108.DOI:10.13381/j.cnki.cjm.201701026.HU H W,HUANG Y K.The relationship between gut microbiota and diseases:research progress[J].Chinese Journal of Microbiology,2017,29(1):106-108.DOI:10.13381/j.cnki.cjm.201701026.
[3]LI J,ZHAO F,WANG Y,et al.Gut microbiota dysbiosis contributes to the development of hypertension[J].Microbiome,2017,5(1):14.DOI:10.1186/s40168-016-0222-x.
[4]NATARAJAN N,HORI D,FLAVAHAN S,et al.Microbial short chain fatty acid metabolites lower blood pressure via endothelial G-protein coupled receptor 41[J].Physiol Genomics,2016,48(11):826-834.DOI:10.1152/physiolgenomics.00089.2016.
[5]覃寿学,施容光,农燕丽,等.1995—2014年艾滋病母婴传播问题的中外文献计量学分析[J].中国全科医学,2017,20(20):2500-2505.DOI:10.3969/j.issn.1007-9572.2017.20.015.QIN S X,SHI R G,NONG Y L,et al.Bibliometric analysis of Chinese and foreign literature on mother-to-child transmission of HIV from 1995 to 2014[J].Chinese General Practice,2017,20(20):2500-2505.DOI:10.3969/j.issn.1007-9572.2017.20.015.
[6]冯磊,梁明修,吕相征,等.国科金资助预防医学学科产出SCI论文的文献计量学分析——基于2011—2014年科学引文索引数据[J].公共卫生与预防医学,2017,28(1):71-76.FENG L,LIANG M X,LYU X Z,et al.Bibliometric analysis of papers on SCI of preventive medicine supported by National Natural Science Foundation of China-Based on the Science Citation Index data for 2011—2014[J].Journal of Public Health and Preventive Medicine,2017,28(1):71-76.
[7]方凤贞,李壮苗,戴晓凤,等.脑卒中后抑郁患者音乐疗法的文献计量学分析[J].护理学杂志,2015,30(17):16-19.DOI:10.3870/hlxzz.2015.17.016.FANG F Z,LI Z M,DAI X F,et al.Bibliometric analysis of music therapy on depression among stroke survivors[J].Journal of Nursing Science,2015,30(17):16-19.DOI:10.3870/hlxzz.2015.17.016.
[8]SINOWATZ F.The impact of the impact factor[J].Anat Histol Embryol,2016,45(3):159-160.DOI:10.1111/ahe.12228.
[9]徐红星.《中国科技期刊研究》2008—2012年核心作者群的分析研究[J].中国科技期刊研究,2013,24(6):1074-1078.DOI:10.3969/j.issn.1001-7143.2013.06.010.XU H X.Analysis and study on the core authors of Science Journals in China from 2008 to 2012[J].Chinese Journal of Scientific and Technical Periodicals,2013,24(6):1074-1078.DOI:10.3969/j.issn.1001-7143.2013.06.010.
[10]王斯琪,邓文萍.针灸治未病的文献计量学分析与研究[J].世界科学技术:中医药现代化,2014,16(10):2124-2130.DOI:10.11842/wst.2014.10.012.WANG S Q,DENG W P.Bibliometric analysis and research on preventive treatment of disease in acupuncture and moxibustion[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2014,16(10):2124-2130.DOI:10.11842/wst.2014.10.012.
[11]董丽娟.基于文献计量分析的护理管理基金论文研究[D].太原:山西医科大学,2016.DONG L J.Research of the funded nursing management paper based on bibliometric analysis[D].Taiyuan:Shanxi Medical University,2016.
[12]张思容,王露,何力,等.中国基金资助基础研究的文献计量学分析[J].科教导刊,2015(34):5-8,11.DOI:10.16400/j.cnki.kjdks.2015.12.003.ZHANG S R,WANG L,HE L,et al.Quantitative analysis on basic research papers supported by foundation of China[J].The Guide of Science&Education,2015(34):5-8,11.DOI:10.16400/j.cnki.kjdks.2015.12.003.
[13]谭潇,段春波,郭程然,等.2009—2013年我国老年医学文献关键词分析[J].中华老年医学杂志,2014,33(6):676-679.DOI:10.3760/cma.j.issn.0254-9026.2014.06.032.TAN X,DUAN C B,GUO C R,et al.Analysis on key words of domestic geriatrics literatures from 2009 to 2013[J].Chinese Journal of Geriatrics,2014,33(6):676-679.DOI:10.3760/cma.j.issn.0254-9026.2014.06.032.
[14]吴晓秋,吕娜.基于关键词共现频率的热点分析方法研究[J].情报理论与实践,2012,35(8):115-119.WU X Q,LYU N.Research on the hot spot analysis method based on keyword co-occurrence frequency[J].Information Studies:Theory&Application,2012,35(8):115-119.
[15]YANG T,SANTISTEBAN M M,RODRIGUEZ V,et al.Gut dysbiosis is linked to hypertension[J].Hypertension,2015,65(6):1331-1340.DOI:10.1161/HYPERTENSIONAHA.115.05315.
[16]MIYAMOTO J,KASUBUCHI M,NAKAJIMA A,et al.The role of short-chain fatty acid on blood pressure regulation[J].Curr Opin Nephrol Hypertens,2016,25(5):379-383.DOI:10.1097/MNH.0000000000000246.
[17]KOH A,DE VADDER F,KOVATCHEVA-DATCHARY P,et al.From dietary fiber to host physiology:short-chain fatty acids as key bacterial metabolites[J].Cell,2016,165(6):1332-1345.DOI:10.1016/j.cell.2016.05.041.
[18]KOETH R A,WANG Z,LEVISON B S,et al.Intestinal microbiota metabolism of L-carnitine,a nutrient in red meat,promotes atherosclerosis[J].Nat Med,2013,19(5):576-585.DOI:10.1038/nm.3145.
[19]SANTISTEBAN M M,KIM S,PEPINE C J,et al.Braingut-bone marrow axis:implications for hypertension and related therapeutics[J].Circ Res,2016,118(8):1327-1336.DOI:10.1161/CIRCRESAHA.116.307709.
[20]李兰娟.国际人类微生物组最新研究进展——第五届国际人类微生物组联盟学术会议纪要[J].中华临床感染病杂志,2015,8(2):188-192.DOI:10.3760/cma.j.issn.1674-2397.2015.02.024.LI L J.Advances on human microbiome studies:summary of the 5th Internaltional Human Microbiome Congress[J].Chinese Journal of Clinical Infectious Diseases,2015,8(2):188-192.DOI:10.3760/cma.j.issn.1674-2397.2015.02.024.