淮安市艾滋病抗病毒治疗依从性影响因素研究
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摘要
目的评估疾控管理模式下艾滋病抗病毒治疗患者的服药依从性,并探索其影响因素。方法对2015年3月31日前开始艾滋病抗病毒治疗且仍然在治273例患者开展问卷调查,利用药片计数法和自我报告法,综合判定患者服药依从性并对影响因素进行分析。结果服药依从性好者242例,占88.64%。多因素logistic回归分析显示,初中文化、治疗方案中含依非韦伦、固定服药时间、服药未超固定服药时间2小时以上患者的服药依从性较好(P<0.05)。结论淮安市艾滋病抗病毒治疗患者的服药依从性较高,主要受文化程度、药物及服药认知的影响。
Objective To assess the compliance of antiretroviral therapy and its influential factors among AIDS patients managed by Disease Control and Prevention.Methods A questionnaire based survey was carried out among 273 patients initially received ART before Mar 31 st,2015 and now still in treatment.The compliance to ART was determined by both pill counting method and self-reporting method,the related influential factors were analyzed.Results Of all patients who completed the study,242 patients reported full compliance,accounted for 88.64%.Multivariate logistic regression analysis showed that patients with junior high school education,taking Efavirenz Tablets,with fixed time of medication,or taking the medicine without more than 2 hours later than the fixed time were associated with good compliance(all P<0.05).Conclusion The compliance to ART among AIDS patients in Huaian was relatively high,which was mainly affected by degree of education,drugs and drug perception.
Objective To assess the compliance of antiretroviral therapy and its influential factors among AIDS patients managed by Disease Control and Prevention.Methods A questionnaire based survey was carried out among 273 patients initially received ART before Mar 31 st,2015 and now still in treatment.The compliance to ART was determined by both pill counting method and self-reporting method,the related influential factors were analyzed.Results Of all patients who completed the study,242 patients reported full compliance,accounted for 88.64%.Multivariate logistic regression analysis showed that patients with junior high school education,taking Efavirenz Tablets,with fixed time of medication,or taking the medicine without more than 2 hours later than the fixed time were associated with good compliance(all P<0.05).Conclusion The compliance to ART among AIDS patients in Huaian was relatively high,which was mainly affected by degree of education,drugs and drug perception.
引文
[1]魏红霞,邱涛.艾滋病诊断与治疗[M].南京:东南大学出版社,2014:26.
[2]王骊,乔健健,鮑杏芬,等.124例HIV/AIDS患者3年随访生存调查[J].江苏预防医学,2016,27(5):569-570.
[3]中国疾病预防控制中心,性病艾滋病预防控制中心.国家免费艾滋病抗病毒药物治疗手册[M].4版.北京:人民卫生出版社,2016:22-122.
[4]孙晓云,阮玉华,邢辉,等.艾滋病病人高效抗逆转录病毒治疗依从性的影响因素[J].中国艾滋病性病,2008,14(3):302-304.
[5]刘丽英,张秀,黄磊,等.艾滋病病人抗反转录病毒治疗依从性的研究进展[J].护理研究,2010,24(8):2163-2165.
[6]刘聪,刘普林,姚中兆,等.提高HIV/AIDS抗病毒治疗依从性的理论模型研究[J].中国热带医学,2013,13(3):375-378.
[7]陈敬芳,王惠珍.263例艾滋病患者社会支持与服药依从性的相关性研究[J].护理学报,2014,21(4):1-3.
[8]张冰,马颖,李念念,等.艾滋病病人药物治疗依从性现状及影响因素分析[J].中国卫生事业管理,2013,30(4):295-298.
[9]蓝珂,黄葵,覃善芳.影响艾滋病药物治疗依从性相关因素的多元回归分析[J].现代中西医结合杂志,2011,20(4):432-433.
[10]赵艳秋,傅卓华,赵秀萍,等.苏州市艾滋病抗病毒治疗失败的病例对照研究[J].江苏预防医学,2016,27(4):403-405.
[11]王加龙,单成超,崔明花.宿迁市艾滋病抗病毒治疗患者不同病毒载量组相关知识知晓及行为分析[J].江苏预防医学,2016,27(4):432-433.
[12]陈艳霞,刘钟应,李星明,等.HIV/AIDS病人服药依从性现状及影响因素分析[J].中国艾滋病性病,2015,21(4):268-272.
[13]葛锐,罗建勇,徐文贤,等.嘉兴市艾滋病患者抗病毒治疗服药依从性及其影响因素分析[J].中华疾病控制杂志,2015,19(2):206-208.
[14]李彤,咸云,褚敏捷,等.艾滋病防治领域中的社会网络研究[J].中国健康教育,2016,32(11):1015-1018.
[2]王骊,乔健健,鮑杏芬,等.124例HIV/AIDS患者3年随访生存调查[J].江苏预防医学,2016,27(5):569-570.
[3]中国疾病预防控制中心,性病艾滋病预防控制中心.国家免费艾滋病抗病毒药物治疗手册[M].4版.北京:人民卫生出版社,2016:22-122.
[4]孙晓云,阮玉华,邢辉,等.艾滋病病人高效抗逆转录病毒治疗依从性的影响因素[J].中国艾滋病性病,2008,14(3):302-304.
[5]刘丽英,张秀,黄磊,等.艾滋病病人抗反转录病毒治疗依从性的研究进展[J].护理研究,2010,24(8):2163-2165.
[6]刘聪,刘普林,姚中兆,等.提高HIV/AIDS抗病毒治疗依从性的理论模型研究[J].中国热带医学,2013,13(3):375-378.
[7]陈敬芳,王惠珍.263例艾滋病患者社会支持与服药依从性的相关性研究[J].护理学报,2014,21(4):1-3.
[8]张冰,马颖,李念念,等.艾滋病病人药物治疗依从性现状及影响因素分析[J].中国卫生事业管理,2013,30(4):295-298.
[9]蓝珂,黄葵,覃善芳.影响艾滋病药物治疗依从性相关因素的多元回归分析[J].现代中西医结合杂志,2011,20(4):432-433.
[10]赵艳秋,傅卓华,赵秀萍,等.苏州市艾滋病抗病毒治疗失败的病例对照研究[J].江苏预防医学,2016,27(4):403-405.
[11]王加龙,单成超,崔明花.宿迁市艾滋病抗病毒治疗患者不同病毒载量组相关知识知晓及行为分析[J].江苏预防医学,2016,27(4):432-433.
[12]陈艳霞,刘钟应,李星明,等.HIV/AIDS病人服药依从性现状及影响因素分析[J].中国艾滋病性病,2015,21(4):268-272.
[13]葛锐,罗建勇,徐文贤,等.嘉兴市艾滋病患者抗病毒治疗服药依从性及其影响因素分析[J].中华疾病控制杂志,2015,19(2):206-208.
[14]李彤,咸云,褚敏捷,等.艾滋病防治领域中的社会网络研究[J].中国健康教育,2016,32(11):1015-1018.