早孕末期四维时空关联成像对胎儿先天性心脏病的诊断价值
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摘要
目的观察四维时空关联成像对早孕末期胎儿先天性心脏病筛查检测的诊断价值。方法选取2016年3月~2017年3月于我院经早期初筛怀疑胎儿有先天性心脏病的孕妇94例,并将其随机分为对照组和观察组,每组47例(每组患者的性别、年龄、孕周等差异无统计学差异),两组患者均由同一位经验丰富的超声科医师为其检查。对照组采用常规二维超声法,观察组在常规二维超声检查法的基础上联合四维时空关联成像法为患者进行检查。记录两组患者的诊断结果,与后期随诊结果比较,分析两组检查方法的灵敏度、特异度、准确度。结果对照组诊断结果的灵敏度、特异度、准确度分别为58.06%、66.67%、72.34%;观察组诊断结果的灵敏度、特异度、准确度分别为90.91%、87.50%、93.62%,结果比较差异有统计学意义,P<0.05。结论四维时空关联成像联合常规二维超声对早孕末期胎儿先天性心脏病的检测结果更加准确,灵敏度和特异度均高于常规二维超声法,可以在临床中推广应用。
Objective:To observe the diagnostic value of four-dimensional spatio-temporal correlation imaging in the screening of fetal congenital heart disease in the early stage of early pregnancy. Methods:From March 2016 to March 2017,94 patients with suspected high-risk pregnant women were initially screened in our hospital and randomly divided into control group and observation group,with 47 cases in each group(gender,Age,gestational age and other differences were not statistically different),both groups of patients by the same experienced ultrasound physician for its examination. The control group using conventional twodimensional ultrasound,the observation group on the basis of conventional two-dimensional ultrasound combined with fourdimensional spatio-temporal correlation imaging method for patients to check. Record the diagnostic results of two groups of patients,compared with the results of follow-up,analyze the sensitivity,specificity and accuracy of the two inspection methods. Results:The sensitivity,specificity and accuracy of the diagnostic results of the control group were 58.06%,66.67% and 72.34% respectively. The sensitivity,specificity and accuracy of the diagnostic results of the observation group were 90.91%,87.50% and 93.62% respectively. The results were compared The difference was statistically significant,P<0.05. Conclusion:Fourdimensional spatio-temporal correlation imaging and conventional two-dimensional ultrasound are more accurate in detection of early fetal congenital heart disease in fetuses. Sensitivity and specificity are higher than conventional two-dimensional ultrasound and can be widely applied in clinical practice.
Objective:To observe the diagnostic value of four-dimensional spatio-temporal correlation imaging in the screening of fetal congenital heart disease in the early stage of early pregnancy. Methods:From March 2016 to March 2017,94 patients with suspected high-risk pregnant women were initially screened in our hospital and randomly divided into control group and observation group,with 47 cases in each group(gender,Age,gestational age and other differences were not statistically different),both groups of patients by the same experienced ultrasound physician for its examination. The control group using conventional twodimensional ultrasound,the observation group on the basis of conventional two-dimensional ultrasound combined with fourdimensional spatio-temporal correlation imaging method for patients to check. Record the diagnostic results of two groups of patients,compared with the results of follow-up,analyze the sensitivity,specificity and accuracy of the two inspection methods. Results:The sensitivity,specificity and accuracy of the diagnostic results of the control group were 58.06%,66.67% and 72.34% respectively. The sensitivity,specificity and accuracy of the diagnostic results of the observation group were 90.91%,87.50% and 93.62% respectively. The results were compared The difference was statistically significant,P<0.05. Conclusion:Fourdimensional spatio-temporal correlation imaging and conventional two-dimensional ultrasound are more accurate in detection of early fetal congenital heart disease in fetuses. Sensitivity and specificity are higher than conventional two-dimensional ultrasound and can be widely applied in clinical practice.
引文
[1]王金瑜,赵笔辉,李燕静,等.产前超声在胎儿先天性心脏病筛查中的临床应用价值[J].医学影像学杂志,2016,26(7):1321-1323.
[2]满婷婷,何怡华,孙琳,等.胎儿先天性心脏病对脑血流动力学的影响[J].中国超声医学杂志,2016,32(9):819-821.
[3]朱继红,夏辉,陈英红,等.超声检查与母体血清学联合检测筛查胎儿先天性心脏病[J].中国现代医学杂志,2017,27(13):96-98.
[4]刘覃俊,严必红.彩色多普勒超声筛查胎儿先天性心脏病的临床价值[J].医学影像学杂志,2016,26(4):727-728.
[5]邢杰.探讨心脏超声筛查对胎儿先天性心脏病诊断及临床应用价值[J].中国妇幼保健,2016,31(5):986-987.
[6]Sun,Rong Rong,Liu,Min,Lu,Lei et al.Congenital Heart Disease:Causes,Diagnosis,Symptoms,and Treatments[J].Cell biochemistry and biophysics,2015,72(3):857-860.
[7]周钰昆,王凤兰,张金辉,等.胎儿心脏超声检查在产前筛查中的应用[J].中国妇幼保健,2016,31(23):5178-5180.
[8]Espinoza,J.The role of spatio-temporal imaging correlation(STIC)in the prenatal diagnosis of congenital heart defects[J].Fetal and maternal medicine review,2014,25(1):59-72.
[9]Rolo,Liliam Cristine,Martins Santana,Eduardo Felix,da Silva,Priscila Henriques et al.Fetal cardiac interventricular septum:volume assessment by 3D/4D ultrasound using spatio-temporal image correlation(STIC)and virtual organ computer-aided analysis(VOCAL)[J].The journal of maternal-fetal&neonatal medicine,2015,28(12):1388-1393.
[10]陶珍,魏玲玲,王颖,等.中孕早期胎儿先天性心脏病筛查中四维超声时空关联成像技术的临床应用效果观察[J].中国产前诊断杂志(电子版),2016,8(1):7-10.
[11]谭冰.四维时空关联成像技术在胎儿心脏检查中应用价值[J].世界最新医学信息文摘(连续型电子期刊),2015,(1):25-25,62.
[12]晏冰,杜帆.四维超声时空关联成像在产前早期胎儿先天性心脏病筛查中的应用[J].医学临床研究,2015,7:1391-1392,1395.
[13]卢薇薇.四维超声时空关联成像技术筛查中孕早期胎儿先天性心脏病的临床价值评价[J].中国实用医药,2015,(11):22-23.
[14]赵宏丽.四维彩超技术在筛查胎儿先天性心脏病的应用效果观察[J].当代临床医刊,2016,29(6):2606,2603.
[15]陈晨,方少兵,谢馥香,等.四维彩超技术在产科筛查胎儿先天性心脏病的价值探讨[J].中国产前诊断杂志(电子版),2017,9(1):34-36.
[16]粱凤华.分析四维彩超对胎儿先心病的诊断价值及应用[J].临床医药文献电子杂志,2017,4(48):9436.
[17]郑海江.四维与二维超声检查在胎儿先天性心脏病诊断中的应用效果比较[J].临床医学研究与实践,2017,2(31):136-137.
[18]肖保军.STIC技术在胎儿心脏检查中的临床应用[J].中国产前诊断杂志(电子版),2017,9(1):10-13.
[19]曹伟雅.四维彩色多普勒超声在胎儿先天性心脏病筛查中应用研究[J].现代医用影像学,2017,26(4):1090-1091,1094.
[20]赵蕊,王小燕.彩色多普勒超声在胎儿先天性心脏病筛查中的临床价值分析[J].医学影像学杂志,2016,26(5):934-936.
[2]满婷婷,何怡华,孙琳,等.胎儿先天性心脏病对脑血流动力学的影响[J].中国超声医学杂志,2016,32(9):819-821.
[3]朱继红,夏辉,陈英红,等.超声检查与母体血清学联合检测筛查胎儿先天性心脏病[J].中国现代医学杂志,2017,27(13):96-98.
[4]刘覃俊,严必红.彩色多普勒超声筛查胎儿先天性心脏病的临床价值[J].医学影像学杂志,2016,26(4):727-728.
[5]邢杰.探讨心脏超声筛查对胎儿先天性心脏病诊断及临床应用价值[J].中国妇幼保健,2016,31(5):986-987.
[6]Sun,Rong Rong,Liu,Min,Lu,Lei et al.Congenital Heart Disease:Causes,Diagnosis,Symptoms,and Treatments[J].Cell biochemistry and biophysics,2015,72(3):857-860.
[7]周钰昆,王凤兰,张金辉,等.胎儿心脏超声检查在产前筛查中的应用[J].中国妇幼保健,2016,31(23):5178-5180.
[8]Espinoza,J.The role of spatio-temporal imaging correlation(STIC)in the prenatal diagnosis of congenital heart defects[J].Fetal and maternal medicine review,2014,25(1):59-72.
[9]Rolo,Liliam Cristine,Martins Santana,Eduardo Felix,da Silva,Priscila Henriques et al.Fetal cardiac interventricular septum:volume assessment by 3D/4D ultrasound using spatio-temporal image correlation(STIC)and virtual organ computer-aided analysis(VOCAL)[J].The journal of maternal-fetal&neonatal medicine,2015,28(12):1388-1393.
[10]陶珍,魏玲玲,王颖,等.中孕早期胎儿先天性心脏病筛查中四维超声时空关联成像技术的临床应用效果观察[J].中国产前诊断杂志(电子版),2016,8(1):7-10.
[11]谭冰.四维时空关联成像技术在胎儿心脏检查中应用价值[J].世界最新医学信息文摘(连续型电子期刊),2015,(1):25-25,62.
[12]晏冰,杜帆.四维超声时空关联成像在产前早期胎儿先天性心脏病筛查中的应用[J].医学临床研究,2015,7:1391-1392,1395.
[13]卢薇薇.四维超声时空关联成像技术筛查中孕早期胎儿先天性心脏病的临床价值评价[J].中国实用医药,2015,(11):22-23.
[14]赵宏丽.四维彩超技术在筛查胎儿先天性心脏病的应用效果观察[J].当代临床医刊,2016,29(6):2606,2603.
[15]陈晨,方少兵,谢馥香,等.四维彩超技术在产科筛查胎儿先天性心脏病的价值探讨[J].中国产前诊断杂志(电子版),2017,9(1):34-36.
[16]粱凤华.分析四维彩超对胎儿先心病的诊断价值及应用[J].临床医药文献电子杂志,2017,4(48):9436.
[17]郑海江.四维与二维超声检查在胎儿先天性心脏病诊断中的应用效果比较[J].临床医学研究与实践,2017,2(31):136-137.
[18]肖保军.STIC技术在胎儿心脏检查中的临床应用[J].中国产前诊断杂志(电子版),2017,9(1):10-13.
[19]曹伟雅.四维彩色多普勒超声在胎儿先天性心脏病筛查中应用研究[J].现代医用影像学,2017,26(4):1090-1091,1094.
[20]赵蕊,王小燕.彩色多普勒超声在胎儿先天性心脏病筛查中的临床价值分析[J].医学影像学杂志,2016,26(5):934-936.